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Molecular Representation Learning (MRL) has emerged as a powerful tool for drug and materials discovery in a variety of tasks such as virtual screening and inverse design. While there has been a surge of interest in advancing model-centric…

Chemical Physics · Physics 2023-09-29 Dingshuo Chen , Yanqiao Zhu , Jieyu Zhang , Yuanqi Du , Zhixun Li , Qiang Liu , Shu Wu , Liang Wang

Quantum machine learning algorithms aim to take advantage of quantum computing to improve classical machine learning algorithms. In this paper, we have applied a quantum machine learning algorithm, the variational quantum classifier for the…

High Energy Physics - Lattice · Physics 2025-06-10 He-Xing Yin , Zhi-Yuan Hu , Huan-Huan Zeng , Jia-Bao Guan , Ji-ke Wang

Machine learning (ML) is successful in achieving human-level performance in various fields. However, it lacks the ability to explain an outcome due to its black-box nature. While existing explainable ML is promising, almost all of these…

Machine Learning · Computer Science 2021-03-23 Zhixin Pan , Prabhat Mishra

Scalable persistent memory (PM) has opened up new opportunities for building indexes that operate and persist data directly on the memory bus, potentially enabling instant recovery, low latency and high throughput. When real PM hardware…

Databases · Computer Science 2022-07-29 Yuliang He , Duo Lu , Kaisong Huang , Tianzheng Wang

As CMOS scaling reaches its technological limits, a radical departure from traditional von Neumann systems, which involve separate processing and memory units, is needed in order to significantly extend the performance of today's computers.…

Continual learning aims to alleviate catastrophic forgetting when handling consecutive tasks under non-stationary distributions. Gradient-based meta-learning algorithms have shown the capability to implicitly solve the transfer-interference…

Machine Learning · Computer Science 2022-10-04 Xiaohan Zou , Tong Lin

Recent success in developing increasingly general purpose agents based on sequence models has led to increased focus on the problem of deploying computationally limited agents within the vastly more complex real-world. A key challenge…

Machine Learning · Computer Science 2025-12-23 Geraud Nangue Tasse , Matthew Riemer , Benjamin Rosman , Tim Klinger

Natural spatiotemporal processes can be highly non-stationary in many ways, e.g. the low-level non-stationarity such as spatial correlations or temporal dependencies of local pixel values; and the high-level variations such as the…

Machine Learning · Computer Science 2019-04-23 Yunbo Wang , Jianjin Zhang , Hongyu Zhu , Mingsheng Long , Jianmin Wang , Philip S Yu

A programmable linear resistor with a compact footprint would have profound implications for microelectronics, enabling efficient in-sensor analog signal processing and in-memory computing. Non-volatile memory offers a potential solution…

For decades, conventional computers based on the von Neumann architecture have performed computation by repeatedly transferring data between their processing and their memory units, which are physically separated. As computation becomes…

Emerging Technologies · Computer Science 2018-02-07 Abu Sebastian , Tomas Tuma , Nikolaos Papandreou , Manuel Le Gallo , Lukas Kull , Thomas Parnell , Evangelos Eleftheriou

Computing-in-Memory (CIM) accelerators are a promising solution for accelerating Machine Learning (ML) workloads, as they perform Matrix-Vector Multiplications (MVMs) on crossbar arrays directly in memory. Although the bit widths of the…

Machine Learning · Computer Science 2026-03-20 Rebecca Pelke , Joel Klein , Jose Cubero-Cascante , Nils Bosbach , Jan Moritz Joseph , Rainer Leupers

The future of main memory appears to lie in the direction of new non-volatile memory technologies that provide strong capacity-to-performance ratios, but have write operations that are much more expensive than reads in terms of energy,…

Data Structures and Algorithms · Computer Science 2018-06-28 Yan Gu , Yihan Sun , Guy E. Blelloch

Analog error correction codes have been proposed for analog in-memory computing on resistive crossbars, which can accelerate vector-matrix multiplication for machine learning. Unlike traditional communication or storage channels, this…

Information Theory · Computer Science 2026-05-29 Ziyuan Zhu , Changcheng Yuan , Ron M. Roth , Paul H. Siegel , Anxiao Jiang

Memory-centric computing aims to enable computation capability in and near all places where data is generated and stored. As such, it can greatly reduce the large negative performance and energy impact of data access and data movement, by…

Hardware Architecture · Computer Science 2024-12-30 Onur Mutlu , Ataberk Olgun , Geraldo F. Oliveira , Ismail Emir Yuksel

The increasing computational demand of Deep Learning has propelled research in special-purpose inference accelerators based on emerging non-volatile memory (NVM) technologies. Such NVM crossbars promise fast and energy-efficient in-situ…

Emerging Technologies · Computer Science 2021-03-17 Deboleena Roy , Indranil Chakraborty , Timur Ibrayev , Kaushik Roy

This paper explores the implications of employing non-volatile memory (NVM) as primary storage for a data base management system (DBMS). We investigate the modifications necessary to be applied on top of a traditional relational DBMS to…

Databases · Computer Science 2025-02-14 Naveed Ul Mustafa , Adri`a Armejach , Ozcan Ozturk , Adrian Cristal , Osman S. Unsal

As power management has become a primary concern in modern data centers, computing resources are being scaled dynamically to minimize energy consumption. We initiate the study of a variant of the classic online speed scaling problem, in…

Machine Learning · Computer Science 2020-10-23 Étienne Bamas , Andreas Maggiori , Lars Rohwedder , Ola Svensson

Memristors provide a tempting solution for weighted synapse connections in neuromorphic computing due to their size and non-volatile nature. However, memristors are unreliable in the commonly used voltage-pulse-based programming approaches…

Neural and Evolutionary Computing · Computer Science 2023-09-08 Hritom Das , Rocco D. Febbo , SNB Tushar , Nishith N. Chakraborty , Maximilian Liehr , Nathaniel Cady , Garrett S. Rose

As it is pretty sure that Moore's law will end some day, questioning about the post-Moore era is more than interesting. Similarly, looking for new computing paradigms that could provide solutions is important. Revisiting the history of…

Emerging Technologies · Computer Science 2022-06-08 Daniel Etiemble

Due to the scaling problem of the DRAM technology, non-volatile memory devices, which are based on different principle of operation than DRAM, are now being intensively developed to expand the main memory of computers. Disaggregated memory…

Hardware Architecture · Computer Science 2023-09-14 Takahiro Hirofuchi , Takaaki Fukai , Akram Ben Ahmed , Ryousei Takano , Kento Sato