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Purpose: Electron density is the most important tissue property influencing photon and ion dose distributions in radiotherapy patients. Dual-energy computed tomography (DECT) enables the determination of electron density by combining the…

Medical Physics · Physics 2017-06-29 Christian Möhler , Patrick Wohlfahrt , Christian Richter , Steffen Greilich

Although cone-beam CT (CBCT) has been used to guide irradiation for pre-clinical radiotherapy(RT) research, it is limited to localize soft tissue target especially in a low imaging contrast environment. Knowledge of target shape is a…

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

Computed Tomography (CT) imaging is one of the most influential diagnostic methods. In clinical reconstruction, an effective energy is used instead of total X-ray spectrum. This approximation causes an accuracy decline. To increase the…

Emerging Technologies · Computer Science 2018-07-25 Neda Gholami , Mohammad Mahdi Dehshibi , Mahmood Fazlali , Antonio Rueda-Toicen , Hector Zenil , Andrew Adamatzky

During spinal fusion surgery, screws are placed close to critical nerves suggesting the need for highly accurate screw placement. Verifying screw placement on high-quality tomographic imaging is essential. C-arm Cone-beam CT (CBCT) provides…

Computer Vision and Pattern Recognition · Computer Science 2022-01-20 Mareike Thies , Jan-Nico Zäch , Cong Gao , Russell Taylor , Nassir Navab , Andreas Maier , Mathias Unberath

Differentiation of breast tissues is challenging in X-ray imaging because tissues might share similar or even the same linear attenuation coefficients $\mu$. Spectral computed tomography (CT) allows for more quantitative characterization in…

Background: Dual-energy (DE) imaging techniques in cone-beam computed tomography (CBCT) have potential clinical applications, including material quantification and improved tissue visualization. However, the performance of DE CBCT is…

Medical Physics · Physics 2023-06-26 Cem Altunbas

Cardiovascular disease (CVD) is a leading cause of mortality worldwide. Electrocardiograms (ECGs) are the most widely used non-invasive tool for cardiac assessment, yet large, well-annotated ECG corpora are scarce due to cost, privacy, and…

Machine Learning · Computer Science 2025-11-14 Xiaoda Wang , Kaiqiao Han , Yuhao Xu , Xiao Luo , Yizhou Sun , Wei Wang , Carl Yang

Objective: To propose a CBCT dose optimization method using readily available measurement equipment in radiation oncology departments. Approach: A 0.6cc air kerma (Kair) calibrated Farmer chamber measured Kair at isocenter for five default…

Medical Physics · Physics 2025-02-04 S. Gros , J. Bian , J. Jackson , M. Delafuente , H. Kang , W. Small , M. Mahesh

Cone-beam CT (CBCT) provides on-board volumetric anatomy for image guidance and treatment adaptation in radiotherapy. To compensate for respiration-induced anatomical motion, time-resolved CBCT is highly desired to capture the…

Medical Physics · Physics 2025-11-05 Ruizhi Zuo , Hua-Chieh Shao , You Zhang

Sparse-view Computed Tomography (CT) image reconstruction is a promising approach to reduce radiation exposure, but it inevitably leads to image degradation. Although diffusion model-based approaches are computationally expensive and suffer…

Image and Video Processing · Electrical Eng. & Systems 2024-03-15 Hanyu Chen , Zhixiu Hao , Lin Guo , Liying Xiao

Compared with conventional single-energy computed tomography (CT), dual-energy CT (DECT) provides better material differentiation but most DECT imaging systems require dual full-angle projection data at different X-ray spectra. Relaxing the…

Early identification of head and neck cancer (HNC) patients who would experience significant anatomical change during radiotherapy (RT) is important to optimize patient clinical benefit and treatment resources. This study aims to assess the…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Meixu Chen , Kai Wang , Michael Dohopolski , Howard Morgan , David Sher , Jing Wang

Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

Computed tomography (CT) to cone-beam computed tomography (CBCT) deformable image registration (DIR) is a crucial step in adaptive radiation therapy. Current intensity-based registration algorithms, such as demons, may fail in the context…

Medical Physics · Physics 2017-08-23 Xin Zhen , Xuejun Gu , Hao Yan , Linghong Zhou , Xun Jia , Steve B. Jiang

The cone beam computed tomography (CBCT) technique was first inserted in dental imaging 15 years ago. Due to this technique 3D imaging in dentistry has been excessively changed. The purpose beyond using CBCT instead of computed tomography…

Medical Physics · Physics 2018-12-11 Kaspar Höschel , Janos Juhasz

Computed tomography (CT) has been developed as a non-destructive technique for observing minute internal images of samples. It has been difficult to obtain photo-realistic (clean or clear) CT images due to various unwanted artifacts…

Quantum Physics · Physics 2023-09-12 Kyungtaek Jun

Recently, interest in MR-only treatment planning using synthetic CTs (synCTs) has grown rapidly in radiation therapy. However, developing class solutions for medical images that contain atypical anatomy remains a major limitation. In this…

Image and Video Processing · Electrical Eng. & Systems 2021-04-16 Hajar Emami , Ming Dong , Carri K. Glide-Hurst

Cardiac computed tomography (CT) has emerged as a major imaging modality for the diagnosis and monitoring of cardiovascular diseases. High temporal resolution is essential to ensure diagnostic accuracy. Limited-angle data acquisition can…

Image and Video Processing · Electrical Eng. & Systems 2025-03-12 Shuo Han , Yongshun Xu , Dayang Wang , Bahareh Morovati , Li Zhou , Jonathan S. Maltz , Ge Wang , Hengyong Yu

Cone beam computed tomography (CBCT) has been widely used in clinical practice, especially in dental clinics, while the radiation dose of X-rays when capturing has been a long concern in CBCT imaging. Several research works have been…

Image and Video Processing · Electrical Eng. & Systems 2022-12-01 Yu Fang , Lanzhuju Mei , Changjian Li , Yuan Liu , Wenping Wang , Zhiming Cui , Dinggang Shen