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The development of neurologically active drugs faces a challenge in treating brain diseases due to the blood-brain barrier's impermeability. High-intensity focused ultrasound can open the barrier in a targeted manner, expanding treatment…
Focused ultrasound stimulated microbubbles have been shown to be capable of inducing blood flow shutdown and necrosis in a range of tissue types in an approach termed antivascular ultrasound or mechanical ablation. In oncology, this…
Functional ultrasound imaging (fUSI) is a cutting-edge technology that measures changes in cerebral blood volume (CBV) by detecting backscattered echoes from red blood cells moving within its field of view (FOV). It offers high…
We propose an ultrasound approach which provides, with one single examination and one single device, access to three bone biomarkers: anatomy, tissue quality and blood flow. It unlocks ultrasound imaging inside bone by accounting for…
Drug delivery to the brain is limited by the blood-brain barrier (BBB). We developed a capacitive micromachined ultrasonic transducer (CMUT)-based transcranial focused ultrasound system capable of both delivering therapy via BBB opening and…
Computational ultrasound imaging (cUSi) with few elements and spatial field encoding can provide high-resolution volumetric B-mode imaging. In this work, we extend its application to 4D carotid artery (CA) flow imaging using a custom…
Registration of longitudinal brain MRI scans containing pathologies is challenging due to dramatic changes in tissue appearance. Although there has been progress in developing general-purpose medical image registration techniques, they have…
Four-dimensional ultrasound imaging of complex biological systems such as the brain is technically challenging because of the spatiotemporal sampling requirements. We present computational ultrasound imaging (cUSi), a new imaging method…
The CT perfusion (CTP) is a medical exam for measuring the passage of a bolus of contrast solution through the brain on a pixel-by-pixel basis. The objective is to draw "perfusion maps" (namely cerebral blood volume, cerebral blood flow and…
Accurate segmentation and classification of brain tumors from Magnetic Resonance Imaging (MRI) remain key challenges in medical image analysis, primarily due to the lack of high-quality, balanced, and diverse datasets with expert…
Electrical impedance tomography (EIT) is a promising technique for biomedical imaging. The strength of EIT is its ability to reconstruct images of the body's internal structures through radiation-safe techniques. EIT is regarded as safe for…
Objective. This study conduct an extensive Brain-computer interfaces (BCI) reproducibility analysis on open electroencephalography datasets, aiming to assess existing solutions and establish open and reproducible benchmarks for effective…
Purpose: We aimed to develop a data-driven multiomics approach integrating radiomics, dosiomics, and delta features to predict treatment response at an earlier stage (intra-treatment) for brain metastases (BMs) patients treated with PULSAR.…
Motor brain-computer interfaces (BCIs) enable the control of external devices by decoding neural signals. However, most existing systems rely on a direct "brain-machine" mapping, overlooking the hierarchical physiological pathway of natural…
Non-invasive imaging of deep blood vessels for mapping hemodynamics remains an open quest in biomedical optical imaging. Although pure optical imaging techniques offer rich optical contrast of blood and have been reported to measure blood…
Cerebrovascular disease is a leading cause of death globally. Prevention and early intervention are known to be the most effective forms of its management. Non-invasive imaging methods hold great promises for early stratification, but at…
Purpose: Registration and segmentation of magnetic resonance (MR) and ultrasound (US) images play an essential role in surgical planning and resection of brain tumors. However, validating these techniques is challenging due to the scarcity…
Segmentation of medical images is a fundamental task with numerous applications. While MRI, CT, and PET modalities have significantly benefited from deep learning segmentation techniques, more recent modalities, like functional ultrasound…
One of the most important tasks in medical image processing is the brain's whole tumor segmentation. It assists in quicker clinical assessment and early detection of brain tumors, which is crucial for lifesaving treatment procedures of…
A myriad of algorithms for the automatic analysis of brain MR images is available to support clinicians in their decision-making. For brain tumor patients, the image acquisition time series typically starts with an already pathological…