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Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

Cartilage degeneration in joints causing pain and various types of knee problems is a serious problem-affecting people in all ages. Degenerated articular cartilage is also known as a central hallmark of osteoarthritis, which is a complex…

Applied Physics · Physics 2019-12-16 Abhishek Ranjan , Chengxiang peng , Anowarul Habib , Sanat Wagle , Frank Melandso

Surface-based cortical analysis is valuable for a variety of neuroimaging tasks, such as spatial normalization, parcellation, and gray matter (GM) thickness estimation. However, most tools for estimating cortical surfaces work exclusively…

Radiographic knee alignment (KA) measurement is important for predicting joint health and surgical outcomes after total knee replacement. Traditional methods for KA measurements are manual, time-consuming and require long-leg radiographs.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Zhisen Hu , Dominic Cullen , Peter Thompson , David Johnson , Chang Bian , Aleksei Tiulpin , Timothy Cootes , Claudia Lindner

Aortic shape analysis plays a key role in cardiovascular diagnostics, treatment planning, and understanding disease progression. We present a robust, fully automated pipeline for aortic shape analysis from cardiac MRI, combining deep…

Tissues and Organs · Quantitative Biology 2025-09-15 Nairouz Shehata , Amr Elsawy , Mohamed Nagy , Muhammad ElMahdy , Mariam Ali , Soha Romeih , Heba Aguib , Magdi Yacoub , Ben Glocker

Tissue characterisation with CMR parametric mapping has the potential to detect and quantify both focal and diffuse alterations in myocardial structure not assessable by late gadolinium enhancement. Native T1 mapping in particular has shown…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Esther Puyol Anton , Bram Ruijsink , Christian F. Baumgartner , Matthew Sinclair , Ender Konukoglu , Reza Razavi , Andrew P. King

Knee osteoporosis weakens the bone tissue in the knee joint, increasing fracture risk. Early detection through X-ray images enables timely intervention and improved patient outcomes. While some researchers have focused on diagnosing knee…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Ayesha Siddiqua , Rakibul Hasan , Anichur Rahman , Abu Saleh Musa Miah

Segmenting anatomical structures in medical images has been successfully addressed with deep learning methods for a range of applications. However, this success is heavily dependent on the quality of the image that is being segmented. A…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Ilkay Oksuz , James R. Clough , Bram Ruijsink , Esther Puyol Anton , Aurelien Bustin , Gastao Cruz , Claudia Prieto , Andrew P. King , Julia A. Schnabel

Tissue awareness has a great demand to improve surgical accuracy in minimally invasive procedures. In arthroscopy, it is one of the challenging tasks due to surgical sites exhibit limited features and textures. Moreover, arthroscopic…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Shahnewaz Ali , Ross Crawford , Frederic Maire , Assoc. Ajay K. Pandey

A shape filter is presented to repair segmentation results obtained in calcium imaging of neurons in vivo. This post-segmentation algorithm can automatically smooth the shapes obtained from a preliminary segmentation, while precluding the…

Image and Video Processing · Electrical Eng. & Systems 2018-06-04 Jie Wang , Zhongxiao Fu , Nasrin Sadeghzadehyazdi , Jonathan Kipnis , Scott T. Acton

This paper puts forth a new formulation and algorithm for the elastic matching problem on unparametrized curves and surfaces. Our approach combines the frameworks of square root normal fields and varifold fidelity metrics into a novel…

Differential Geometry · Mathematics 2019-03-05 Martin Bauer , Nicolas Charon , Philipp Harms

The reconstruction of cerebral cortex surfaces from brain MRI scans is instrumental for the analysis of brain morphology and the detection of cortical thinning in neurodegenerative diseases like Alzheimer's disease (AD). Moreover, for a…

Neurons and Cognition · Quantitative Biology 2022-10-05 Anne-Marie Rickmann , Fabian Bongratz , Sebastian Pölsterl , Ignacio Sarasua , Christian Wachinger

The ability to map left ventricle (LV) myocardial motion using computed tomography angiography (CTA) is essential to diagnosing cardiovascular conditions and guiding interventional procedures. Due to their inherent locality, conventional…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Shahar Zuler , Shai Tejman-Yarden , Dan Raviv

Knee Osteoarthritis (KOA) is a prevalent musculoskeletal disorder that severely impacts mobility and quality of life, particularly among older adults. Its diagnosis often relies on subjective assessments using the Kellgren-Lawrence (KL)…

Image and Video Processing · Electrical Eng. & Systems 2025-01-17 Zhe Wang , Aladine Chetouani , Yung Hsin Chen , Yuhua Ru , Fang Chen , Mohamed Jarraya , Fabian Bauer , Liping Zhang , Didier Hans , Rachid Jennane

Knee Osteoarthritis (KOA) is the third most prevalent Musculoskeletal Disorder (MSD) after neck and back pain. To monitor such a severe MSD, a segmentation map of the femur, tibia and tibiofemoral cartilage is usually accessed using the…

Image and Video Processing · Electrical Eng. & Systems 2024-01-24 Akshay Daydar , Alik Pramanick , Arijit Sur , Subramani Kanagaraj

Corneal thickness (pachymetry) maps can be used to monitor restoration of corneal endothelial function, for example after Descemet's membrane endothelial keratoplasty (DMEK). Automated delineation of the corneal interfaces in anterior…

Knee osteoarthritis (OA) is one of the most common musculoskeletal disorders and requires early-stage diagnosis. Nowadays, the deep convolutional neural networks have achieved greatly in the computer-aided diagnosis field. However, the…

Image and Video Processing · Electrical Eng. & Systems 2020-10-13 Jiayu Huo , Liping Si , Xi Ouyang , Kai Xuan , Weiwu Yao , Zhong Xue , Qian Wang , Dinggang Shen , Lichi Zhang

Kinetic modeling enables \textit{in vivo} quantification of tracer uptake and glucose metabolism in [${}^{18}$F]Fluorodeoxyglucose ([${}^{18}$F]FDG) dynamic positron emission tomography (dPET) imaging of mice. However, kinetic modeling…

Quantitative Methods · Quantitative Biology 2025-10-27 Christian Salomonsen , Kristoffer K. Wickstrøm , Samuel Kuttner , Elisabeth Wetzer

We present MultiMorph, a fast and efficient method for constructing anatomical atlases on the fly. Atlases capture the canonical structure of a collection of images and are essential for quantifying anatomical variability across…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 S. Mazdak Abulnaga , Andrew Hoopes , Neel Dey , Malte Hoffmann , Marianne Rakic , Bruce Fischl , John Guttag , Adrian Dalca

Motion-related artifacts are inevitable in Magnetic Resonance Imaging (MRI) and can bias automated neuroanatomical metrics such as cortical thickness. These biases can interfere with statistical analysis which is a major concern as motion…

Image and Video Processing · Electrical Eng. & Systems 2025-06-11 Charles Bricout , Samira Ebrahimi Kahou , Sylvain Bouix