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In Machine Learning as a Service, a provider trains a deep neural network and gives many users access. The hosted (source) model is susceptible to model stealing attacks, where an adversary derives a surrogate model from API access to the…

Machine Learning · Computer Science 2021-01-21 Nils Lukas , Yuxuan Zhang , Florian Kerschbaum

Graph embedding methods aim at finding useful graph representations by mapping nodes to a low-dimensional vector space. It is a task with important downstream applications, such as link prediction, graph reconstruction, data visualization,…

Machine Learning · Computer Science 2022-09-13 Said Kerrache , Hafida Benhidour

This paper addresses the challenging problem of retrieval and matching of graph structured objects, and makes two key contributions. First, we demonstrate how Graph Neural Networks (GNN), which have emerged as an effective model for various…

Machine Learning · Computer Science 2019-05-14 Yujia Li , Chenjie Gu , Thomas Dullien , Oriol Vinyals , Pushmeet Kohli

Graph neural networks (GNNs) have emerged as powerful tools for learning protein structures by capturing spatial relationships at the residue level. However, existing GNN-based methods often face challenges in learning multiscale…

Machine Learning · Computer Science 2026-02-03 Shih-Hsin Wang , Yuhao Huang , Taos Transue , Justin Baker , Jonathan Forstater , Thomas Strohmer , Bao Wang

Developing scalable solutions for training Graph Neural Networks (GNNs) for link prediction tasks is challenging due to the high data dependencies which entail high computational cost and huge memory footprint. We propose a new method for…

Machine Learning · Computer Science 2022-01-11 Nasrullah Sheikh , Xiao Qin , Berthold Reinwald , Chuan Lei

Graph neural networks (GNNs) are widely used for learning node embeddings in graphs, typically adopting a message-passing scheme. This approach, however, leads to the neighbor explosion problem, with exponentially growing computational and…

Machine Learning · Computer Science 2025-07-08 Zichao Yue , Chenhui Deng , Zhiru Zhang

Advances in machine learning have led to graph neural network-based methods for drug discovery, yielding promising results in molecular design, chemical synthesis planning, and molecular property prediction. However, current graph neural…

Quantitative Methods · Quantitative Biology 2021-07-13 Jiahua Rao , Shuangjia Zheng , Yuedong Yang

Molecular interaction networks are powerful resources for the discovery. They are increasingly used with machine learning methods to predict biologically meaningful interactions. While deep learning on graphs has dramatically advanced the…

Molecular Networks · Quantitative Biology 2020-12-10 Kexin Huang , Cao Xiao , Lucas Glass , Marinka Zitnik , Jimeng Sun

Purpose: Neural networks have received recent interest for reconstruction of undersampled MR acquisitions. Ideally network performance should be optimized by drawing the training and testing data from the same domain. In practice, however,…

Computer Vision and Pattern Recognition · Computer Science 2019-05-07 Salman Ul Hassan Dar , Muzaffer Özbey , Ahmet Burak Çatlı , Tolga Çukur

Graph neural networks (GNNs) have emerged as a powerful approach for solving many network mining tasks. However, learning on large graphs remains a challenge - many recently proposed scalable GNN approaches rely on an expensive…

We introduce a convolutional neural network that operates directly on graphs. These networks allow end-to-end learning of prediction pipelines whose inputs are graphs of arbitrary size and shape. The architecture we present generalizes…

Coronavirus disease 2019 (COVID-19) has spread all over the world for three years, but medical facilities in many areas still aren't adequate. There is a need for rapid COVID-19 diagnosis to identify high-risk patients and maximize the use…

Image and Video Processing · Electrical Eng. & Systems 2023-04-27 Lin Yang , Shuihua Wang , Yudong Zhang

Generative deep learning has become pivotal in molecular design for drug discovery, materials science, and chemical engineering. A widely used paradigm is to pretrain neural networks on string representations of molecules and fine-tune them…

Machine Learning · Computer Science 2025-03-21 Jonathan Pirnay , Jan G. Rittig , Alexander B. Wolf , Martin Grohe , Jakob Burger , Alexander Mitsos , Dominik G. Grimm

Coronavirus Disease 2019 (COVID-19) has been creating a worldwide pandemic situation. Repurposing drugs, already shown to be free of harmful side effects, for the treatment of COVID-19 patients is an important option in launching novel…

Molecular Networks · Quantitative Biology 2020-07-07 Sumanta Ray , Snehalika Lall , Anirban Mukhopadhyay , Sanghamitra Bandyopadhyay , Alexander Schönhuth

This paper analyses a set of simple adaptations that transform standard message-passing Graph Neural Networks (GNN) into provably powerful directed multigraph neural networks. The adaptations include multigraph port numbering, ego IDs, and…

Machine Learning · Computer Science 2024-01-05 Béni Egressy , Luc von Niederhäusern , Jovan Blanusa , Erik Altman , Roger Wattenhofer , Kubilay Atasu

Drug combination therapy has become a increasingly promising method in the treatment of cancer. However, the number of possible drug combinations is so huge that it is hard to screen synergistic drug combinations through wet-lab…

Machine Learning · Computer Science 2021-07-07 J. Wang , X. Liu , S. Shen , L. Deng , H. Liu*

Advancements in neural machinery have led to a wide range of algorithmic solutions for molecular property prediction. Two classes of models in particular have yielded promising results: neural networks applied to computed molecular…

Predicting drug-gene associations is crucial for drug development and disease treatment. While graph neural networks (GNN) have shown effectiveness in this task, they face challenges with data sparsity and efficient contrastive learning…

Machine Learning · Computer Science 2025-02-14 Jiayang Wu , Wensheng Gan , Philip S. Yu

Data-driven soft sensors help in process operations by providing real-time estimates of otherwise hard- to-measure process quantities, e.g., viscosities or product concentrations. Currently, soft sensors need to be developed individually…

Machine Learning · Computer Science 2025-02-12 Maximilian F. Theisen , Gabrie M. H. Meesters , Artur M. Schweidtmann

Graph Neural Networks (GNNs) have achieved promising results in tasks such as node classification and graph classification. However, recent studies reveal that GNNs are vulnerable to backdoor attacks, posing a significant threat to their…

Machine Learning · Computer Science 2025-03-13 Zhiwei Zhang , Minhua Lin , Junjie Xu , Zongyu Wu , Enyan Dai , Suhang Wang
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