English
Related papers

Related papers: Using Single Molecule Imaging to Explore Intracell…

200 papers

We probe the dynamics of dissociating CS$_2$ molecules across the entire reaction pathway upon excitation. Photoelectron spectroscopy measurements using laboratory-generated femtosecond extreme ultraviolet pulses monitor the competing…

Information transmission in cells occurs quite accurately even when concentration changes are "read" by individual target molecules. In this Letter we study molecule number fluctuations when molecules diffuse and react. We show that, for…

Biological Physics · Physics 2014-12-17 Emiliano Pérez Ipiña , Silvina Ponce Dawson

Movement behavior of biological entities plays a crucial role in their destiny through regulating their intraspecific and interspecific interactions as well as their interaction with surrounding environment. In spite of various models for…

Tissues and Organs · Quantitative Biology 2017-11-10 Youness Azimzade

We investigate how vibration affects molecular photoemission dynamics, through simulations on two-dimension asymmetric model molecules including the electronic and nuclear motions in a fully correlated way. We show that a slight anisotropy…

Chemical Physics · Physics 2024-02-14 Antoine Desrier , Morgan Berkane , Camille Lévêque , Richard Taïeb , Jérémie Caillat

Cell polarity and movement are fundamental to many biological functions. Experimental and theoretically studies have indicated that interactions of certain proteins lead to the cell polarization which plays a key role in controlling the…

Dynamical Systems · Mathematics 2022-08-12 Shuang Liu , Li-Tien Cheng , Bo Li

Experimental measurements of particle dynamics on the lower surface of a 3D Couette cell containing monodisperse spheres are reported. The average radial density and velocity profiles are similar to those previously measured within the bulk…

Soft Condensed Matter · Physics 2007-05-23 Daniel M. Mueth

Macromolecules change their shape (conformation) in the process of carrying out their functions. The imaging by cryo-electron microscopy of rapidly-frozen, individual copies of macromolecules (single particles) is a powerful and general…

Biomolecules · Quantitative Biology 2022-11-22 Bogdan Toader , Fred J. Sigworth , Roy R. Lederman

General discrete one-dimensional stochastic models to describe the transport of single molecules along coupled parallel lattices with period $N$ are developed. Theoretical analysis that allows to calculate explicitly the steady-state…

Soft Condensed Matter · Physics 2009-11-11 Evgeny B. Stukalin , Anatoly B. Kolomeisky

We introduce MOSCITO (MOlecular Dynamics Subspace Clustering with Temporal Observance), a subspace clustering for molecular dynamics data. MOSCITO groups those timesteps of a molecular dynamics trajectory together into clusters in which the…

Machine Learning · Computer Science 2025-01-03 Anna Beer , Martin Heinrigs , Claudia Plant , Ira Assent

Self-propelled swimmers such as bacteria agglomerate into clusters as a result of their persistent motion. In 1D, those clusters do not coalesce macroscopically and the stationary cluster size distribution (CSD) takes an exponential form.…

Soft Condensed Matter · Physics 2021-09-20 Pablo de Castro , Francisco M. Rocha , Saulo Diles , Rodrigo Soto , Peter Sollich

Cell membranes separate the cell interior from the external environment. They are constituted by a variety of lipids; their composition determines the dynamics of membrane proteins and affects the ability of the cells to adapt. Even though…

Quantitative Methods · Quantitative Biology 2018-10-04 Nicola Galvanetto

Membrane proteins often need to be inserted into or attached on the cell membrane to perform their functions. Understanding their transmembrane topology and conformational dynamics during insertion is crucial for elucidating their roles.…

Biological Physics · Physics 2024-12-30 C. Yang , D. Ma , S. Hu , M. Li , Y. Lu

The dispersive interaction of atoms and a far-detuned light field allows nondestructive imaging of the density oscillations in Bose-Einstein condensates. Starting from a ground state condensate, we investigate how the measurement back…

Quantum Physics · Physics 2015-08-05 Andrew C. J. Wade , Jacob F. Sherson , Klaus Mølmer

A cell is polarised when it has developed a main axis of organisation through the reorganisation of its cytosqueleton and its intracellular organelles. Polarisation can occur spontaneously or be triggered by external signals, like gradients…

Analysis of PDEs · Mathematics 2013-01-17 Vincent Calvez , Nicolas Meunier , Nicolas Muller , Raphael Voituriez

Single molecular motor kinesin harnesses thermal and non-thermal fluctuations to transport various cargoes along microtubules, converting chemical energy to directed movements. To describe the non-thermal fluctuations generated by the…

Soft Condensed Matter · Physics 2022-12-20 Mengkai Feng , Zhonghuai Hou

The interactions between diffusing molecules and membrane-bound receptors drive numerous cellular processes. In this work, we develop a spatial model of molecular interactions with membrane receptors by homogenizing the cell membrane and…

Quantitative Methods · Quantitative Biology 2025-01-24 Anil Cengiz , Sean D Lawley

Chemotaxis combines three processes: directional sensing, polarity reorientation and migration. Directed migration plays an important role in immune response, metastasis, wound healing and development. To describe chemotaxis, we extend a…

Biological Physics · Physics 2023-12-04 Pedro C. Dal-Castel , Gilberto L. Thomas , Gabriel C. Perrone , Rita M. C. de Almeida

Bacterial colonies are a well-known example of living active matter, exhibiting collective behaviors such as nematic alignment and collective motion that play an important role in the spread of microbial infections. While the underlying…

Cells sense environmental signals and transmit information intracellularly through changes in the abundance of molecular components. Such molecular abundances can be measured in single cells and exhibit significant heterogeneity in clonal…

Quantitative Methods · Quantitative Biology 2024-09-27 Raymond Fan , Andreas Hilfinger

The filtration of fluid in 2D porous medium is simulated by the molecular dynamics technique. The high concentration of fluid is created at the initial point in time and the number of fluid particles is investigated in all porous. The…

Fluid Dynamics · Physics 2007-05-23 Marat N. Ovchinnikov