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Timely and accurate lymphoma diagnosis is essential for guiding cancer treatment. Standard diagnostic practice combines hematoxylin and eosin (HE)-stained whole slide images with immunohistochemistry, flow cytometry, and molecular genetic…
Molecular subtyping of breast cancer is crucial for personalized treatment and prognosis. Traditional classification approaches rely on either histopathological images or gene expression profiling, limiting their predictive power. In this…
Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…
Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…
Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…
We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…
Lymphoma diagnosis, particularly distinguishing between subtypes, is critical for effective treatment but remains challenging due to the subtle morphological differences in histopathological images. This study presents a novel hybrid deep…
Histopathology remains the gold standard for cancer diagnosis and prognosis. With the advent of transcriptome profiling, multi-modal learning combining transcriptomics with histology offers more comprehensive information. However, existing…
Learning good representation of giga-pixel level whole slide pathology images (WSI) for downstream tasks is critical. Previous studies employ multiple instance learning (MIL) to represent WSIs as bags of sampled patches because, for most…
Liver cancer is a leading cause of cancer-related mortality worldwide, with its high genetic heterogeneity complicating diagnosis and treatment. This study introduces DLSOM, a deep learning framework utilizing stacked autoencoders to…
Recently, vision transformers were shown to be capable of outperforming convolutional neural networks when pretrained on sufficiently large datasets. Vision transformer models show good accuracy on large scale datasets, with features of…
Histomorphology is crucial in cancer diagnosis. However, existing whole slide image (WSI) classification methods struggle to effectively incorporate histomorphology information, limiting their ability to capture key pathological features.…
This paper proposes a novel multimodal deep learning framework integrating bidirectional LSTM, multi-head attention mechanism, and variational mode decomposition (BiLSTM-AM-VMD) for early liver cancer diagnosis. Using heterogeneous data…
Melanoma diagnosed and treated in its early stages can increase the survival rate. A projected increase in skin cancer incidents and a dearth of dermatopathologists have emphasized the need for computational pathology (CPATH) systems. CPATH…
Classifying breast cancer molecular subtypes is crucial for tailoring treatment strategies. While immunohistochemistry (IHC) and gene expression profiling are standard methods for molecular subtyping, IHC can be subjective, and gene…
In this study, we proposed a deep Swin-Vision Transformer-based transfer learning architecture for robust multi-cancer histopathological image classification. The proposed framework integrates a hierarchical Swin Transformer with…
Vision transformers (ViT) have been shown to allow for more flexible feature detection and can outperform convolutional neural network (CNN) when pre-trained on sufficient data. Due to their promising feature detection capabilities, we…
Brain tumors represent one of the most critical neurological conditions, where early and accurate diagnosis is directly correlated with patient survival rates. Manual interpretation of Magnetic Resonance Imaging (MRI) scans is…
Automatic detection of leukemic B-lymphoblast cancer in microscopic images is very challenging due to the complicated nature of histopathological structures. To tackle this issue, an automatic and robust diagnostic system is required for…
The accurate diagnosis of pathological subtypes of lung cancer is of paramount importance for follow-up treatments and prognosis managements. Assessment methods utilizing deep learning technologies have introduced novel approaches for…