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To meet ongoing cognitive demands, the human brain must seamlessly transition from one brain state to another, in the process drawing on different cognitive systems. How does the brain's network of anatomical connections help facilitate…

Neurons and Cognition · Quantitative Biology 2016-09-08 Richard F. Betzel , Shi Gu , John D. Medaglia , Fabio Pasqualetti , Danielle S. Bassett

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Neurons and Cognition · Quantitative Biology 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

The minimum number of inputs needed to control a network is frequently used to quantify its controllability. Control of linear dynamics through a minimum set of inputs, however, often has prohibitively large energy requirements and there is…

Computational Engineering, Finance, and Science · Computer Science 2022-12-12 Samie Alizadeh , Márton Pósfai , Abdorasoul Ghasemi

Cognitive function is driven by dynamic interactions between large-scale neural circuits or networks, enabling behavior. Fundamental principles constraining these dynamic network processes have remained elusive. Here we use network control…

Neurons and Cognition · Quantitative Biology 2015-10-28 Shi Gu , Fabio Pasqualetti , Matthew Cieslak , Scott T. Grafton , Danielle S. Bassett

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

Neurons and Cognition · Quantitative Biology 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett

Network control theory has recently emerged as a promising approach for understanding brain function and dynamics. By operationalizing notions of control theory for brain networks, it offers a fundamental explanation for how brain dynamics…

Quantitative Methods · Quantitative Biology 2020-03-20 Shikuang Deng , Shi Gu

Despite the significant advances in identifying the driver nodes and energy requiring in network control, a framework that incorporates more complicated dynamics remains challenging. Here, we consider the conformity behavior into network…

Physics and Society · Physics 2022-01-26 Zu-Yu Qian , Cheng Yuan , Jie Zhou , Shi-Ming Chen , Sen Nie

Network controllability is a powerful tool to study causal relationships in complex systems and identify the driver nodes for steering the network dynamics into desired states. However, due to ill-posed conditions, results become unreliable…

The human brain is composed of distinct regions that are each associated with particular functions and distinct propensities for the control of neural dynamics. However, the relation between these functions and control profiles is poorly…

Neurons and Cognition · Quantitative Biology 2020-06-02 Evelyn Tang , Harang Ju , Graham L. Baum , David R. Roalf , Theodore D. Satterthwaite , Fabio Pasqualetti , Danielle S. Bassett

It has recently been shown that the average energy required to control a subset of nodes in a complex network scales exponentially with the cardinality of the subset. While the mean scales exponentially, the variance of the control energy…

Physics and Society · Physics 2018-08-23 Isaac Klickstein , Francesco Sorrentino

Understanding how few distributed areas can steer large-scale brain activity is a fundamental question that has practical implications, which range from inducing specific patterns of behavior to counteracting disease. Recent endeavors based…

Neurons and Cognition · Quantitative Biology 2022-10-11 Giulia Bassignana , Giordano Lacidogna , Paolo Bartolomeo , Olivier Colliot , Fabrizio De Vico Fallani

The question of controllability of natural and man-made network systems has recently received considerable attention. In the context of the human brain, the study of controllability may not only shed light into the organization and function…

Optimization and Control · Mathematics 2021-02-10 Tommaso Menara , Shi Gu , Danielle S. Bassett , Fabio Pasqualetti

Recent advances in computational models of signal propagation and routing in the human brain have underscored the critical role of white matter structure. A complementary approach has utilized the framework of network control theory to…

Neurons and Cognition · Quantitative Biology 2021-03-15 Pragya Srivastava , Erfan Nozari , Jason Z. Kim , Harang Ju , Dale Zhou , Cassiano Becker , Fabio Pasqualetti , Danielle S. Bassett

The control of dynamical, networked systems continues to receive much attention across the engineering and scientific research fields. Of particular interest is the proper way to determine which nodes of the network should receive external…

Systems and Control · Computer Science 2018-08-24 Isaac Klickstein , Francesco Sorrentino

In this paper, we investigate the linear controllability framework for complex networks from a physical point of view. There are three main results. (1) If one applies control signals as determined from the structural controllability…

Systems and Control · Computer Science 2015-09-11 Yu-Zhong Chen , Lezhi Wang , Wenxu Wang , Ying-Cheng Lai

Networked systems display complex patterns of interactions between a large number of components. In physical networks, these interactions often occur along structural connections that link components in a hard-wired connection topology,…

Neurons and Cognition · Quantitative Biology 2018-04-03 Jason Kim , Jonathan M. Soffer , Ari E. Kahn , Jean M. Vettel , Fabio Pasqualetti , Danielle S. Bassett

The aim of this paper is to shed light on the problem of controlling a complex network with minimal control energy. We show first that the control energy depends on the time constant of the modes of the network, and that the closer the…

Systems and Control · Computer Science 2018-03-12 Gustav Lindmark , Claudio Altafini

The human brain is a complex network that supports mental function. The nascent field of network neuroscience applies tools from mathematics to neuroimaging data in the hopes of shedding light on cognitive function. A critical question…

Neurons and Cognition · Quantitative Biology 2017-04-26 John D. Medaglia , Perry Zurn , Walter Sinnott-Armstrong , Danielle S. Bassett

Recently it has been shown that the control energy required to control a dynamical complex network is prohibitively large when there are only a few control inputs. Most methods to reduce the control energy have focused on where, in the…

Systems and Control · Computer Science 2017-05-24 Isaac S. Klickstein , Afroza Shirin , Francesco Sorrentino

Controllability, a basic property of various networked systems, has gained profound theoretical applications in complex social, technological, biological, and brain networks. Yet, little attention has been given to the control trajectory…

Optimization and Control · Mathematics 2018-06-13 Aming Li , Long Wang , Frank Schweitzer
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