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Scientists often use directed acyclic graphs (days) to model the qualitative structure of causal theories, allowing the parameters to be estimated from observational data. Two causal models are equivalent if there is no experiment which…

Artificial Intelligence · Computer Science 2013-04-05 Tom S. Verma , Judea Pearl

New biological assays like Perturb-seq link highly parallel CRISPR interventions to a high-dimensional transcriptomic readout, providing insight into gene regulatory networks. Causal gene regulatory networks can be represented by directed…

Machine Learning · Statistics 2024-02-22 Albert Xue , Jingyou Rao , Sriram Sankararaman , Harold Pimentel

We propose a method to classify the causal relationship between two discrete variables given only the joint distribution of the variables, acknowledging that the method is subject to an inherent baseline error. We assume that the causal…

Machine Learning · Statistics 2016-11-07 Krzysztof Chalupka , Frederick Eberhardt , Pietro Perona

Discovering causal relationships from observational data is a challenging task that relies on assumptions connecting statistical quantities to graphical or algebraic causal models. In this work, we focus on widely employed assumptions for…

Methodology · Statistics 2024-03-20 Jonas Wahl , Urmi Ninad , Jakob Runge

Directed Acyclic Graphs (DAGs) provide a powerful framework to model causal relationships among variables in multivariate settings; in addition, through the do-calculus theory, they allow for the identification and estimation of causal…

Machine Learning · Statistics 2022-01-31 Federico Castelletti , Alessandro Mascaro

Causal discovery, the task of inferring causal structure from data, has the potential to uncover mechanistic insights from biological experiments, especially those involving perturbations. However, causal discovery algorithms over larger…

Machine Learning · Computer Science 2025-04-01 Menghua Wu , Yujia Bao , Regina Barzilay , Tommi Jaakkola

The problem of learning a directed acyclic graph (DAG) up to Markov equivalence is equivalent to the problem of finding a permutation of the variables that induces the sparsest graph. Without additional assumptions, this task is known to be…

Methodology · Statistics 2020-11-10 Chandler Squires , Joshua Amaniampong , Caroline Uhler

Identification and appropriate handling of inconsistencies in data at deployment time is crucial to reliably use machine learning models. While recent data-centric methods are able to identify such inconsistencies with respect to the…

Machine Learning · Computer Science 2024-02-29 Nicolas Huynh , Jeroen Berrevoets , Nabeel Seedat , Jonathan Crabbé , Zhaozhi Qian , Mihaela van der Schaar

Causal discovery from observational data is an important tool in many branches of science. Under certain assumptions it allows scientists to explain phenomena, predict, and make decisions. In the large sample limit, sound and complete…

Machine Learning · Statistics 2021-07-13 Shami Nisimov , Yaniv Gurwicz , Raanan Y. Rohekar , Gal Novik

To make accurate predictions, understand mechanisms, and design interventions in systems of many variables, we wish to learn causal graphs from large scale data. Unfortunately the space of all possible causal graphs is enormous so scalably…

Machine Learning · Statistics 2024-06-19 Alan Nawzad Amin , Andrew Gordon Wilson

We consider graphs that represent pairwise marginal independencies amongst a set of variables (for instance, the zero entries of a covariance matrix for normal data). We characterize the directed acyclic graphs (DAGs) that faithfully…

Artificial Intelligence · Computer Science 2015-08-04 Johannes Textor , Alexander Idelberger , Maciej Liśkiewicz

The discovery of causal relationships from observational data is very challenging. Many recent approaches rely on complexity or uncertainty concepts to impose constraints on probability distributions, aiming to identify specific classes of…

Methodology · Statistics 2024-04-09 Aramayis Dallakyan , Yang Ni

Causal structure learning, also known as causal discovery, aims to estimate causal relationships between variables as a form of a causal directed acyclic graph (DAG) from observational data. One of the major frameworks is the order-based…

Machine Learning · Statistics 2026-02-18 Kentaro Kanamori , Hirofumi Suzuki , Takuya Takagi

Causal discovery amounts to learning a directed acyclic graph (DAG) that encodes a causal model. This model selection problem can be challenging due to its large combinatorial search space, particularly when dealing with non-parametric…

Machine Learning · Statistics 2024-08-21 Yurou Liang , Oleksandr Zadorozhnyi , Mathias Drton

Inferring the structure of directed acyclic graphs (DAGs) from data is a central challenge in causal discovery, particularly in modern high-dimensional settings where large-scale interventional data are increasingly available. While…

Random directed acyclic graphs (DAGs) based on imposing an order on Erd\H{o}s-R\'enyi and scale free random graphs are widely used for evaluating causal discovery algorithms. We show that in such DAGs, the set of nodes reachable via open…

Methodology · Statistics 2026-05-08 Alexander G. Reisach , Antoine Chambaz , Gilles Blanchard , Sebastian Weichwald

This paper concerns the assessment of the effects of actions from a combination of nonexperimental data and causal assumptions encoded in the form of a directed acyclic graph in which some variables are presumed to be unobserved. We provide…

Artificial Intelligence · Computer Science 2012-07-19 Jin Tian

Causal identification is at the core of the causal inference literature, where complete algorithms have been proposed to identify causal queries of interest. The validity of these algorithms hinges on the restrictive assumption of having…

Machine Learning · Computer Science 2023-10-30 Sina Akbari , Fateme Jamshidi , Ehsan Mokhtarian , Matthew J. Vowels , Jalal Etesami , Negar Kiyavash

Observational studies in fields such as epidemiology often rely on covariate adjustment to estimate causal effects. Classical graphical criteria, like the back-door criterion and the generalized adjustment criterion, are powerful tools for…

Methodology · Statistics 2025-12-24 Isabela Belciug , Simon Ferreira , Charles K. Assaad

Evaluating graphs learned by causal discovery algorithms is difficult: The number of edges that differ between two graphs does not reflect how the graphs differ with respect to the identifying formulas they suggest for causal effects. We…

Machine Learning · Statistics 2024-07-12 Leonard Henckel , Theo Würtzen , Sebastian Weichwald
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