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Large language models (LLMs) have attracted significant attention for potential applications in digital health, while their application in mental health is subject to ongoing debate. This systematic review aims to evaluate the usage of LLMs…

Computers and Society · Computer Science 2024-08-14 Zhijun Guo , Alvina Lai , Johan Hilge Thygesen , Joseph Farrington , Thomas Keen , Kezhi Li

The past decade has been transformative for mental health research and practice. The ability to harness large repositories of data, whether from electronic health records (EHR), mobile devices, or social media, has revealed a potential for…

Computation and Language · Computer Science 2023-11-28 Munmun De Choudhury , Sachin R. Pendse , Neha Kumar

Large Language Models (LLMs) are increasingly used for mental health support, yet little is known about how people with mental health challenges engage with them, how they evaluate their usefulness, and what design opportunities they…

Human-Computer Interaction · Computer Science 2026-02-12 Aditya Kumar Purohit , Hendrik Heuer

Although engagement in self-directed wellness exercises typically declines over time, integrating social support such as coaching can sustain it. However, traditional forms of support are often inaccessible due to the high costs and complex…

People experiencing severe distress increasingly use Large Language Model (LLM) chatbots as mental health support tools. Discussions on social media have described how engagements were lifesaving for some, but evidence suggests that…

Human-Computer Interaction · Computer Science 2025-05-12 Inhwa Song , Sachin R. Pendse , Neha Kumar , Munmun De Choudhury

Large Language Models (LLMs) have become valuable assets in mental health, showing promise in both classification tasks and counseling applications. This paper offers a perspective on using LLMs in mental health applications. It discusses…

Computation and Language · Computer Science 2023-12-19 Shaoxiong Ji , Tianlin Zhang , Kailai Yang , Sophia Ananiadou , Erik Cambria

Global rates of mental health concerns are rising, and there is increasing realization that existing models of mental health care will not adequately expand to meet the demand. With the emergence of large language models (LLMs) has come…

Computation and Language · Computer Science 2024-08-02 Hannah R. Lawrence , Renee A. Schneider , Susan B. Rubin , Maja J. Mataric , Daniel J. McDuff , Megan Jones Bell

LGBTQ+ individuals are increasingly turning to chatbots powered by large language models (LLMs) to meet their mental health needs. However, little research has explored whether these chatbots can adequately and safely provide tailored…

Human-Computer Interaction · Computer Science 2024-02-15 Zilin Ma , Yiyang Mei , Yinru Long , Zhaoyuan Su , Krzysztof Z. Gajos

Digital technologies have long been explored as a complement to standard procedure in mental health research and practice, ranging from the management of electronic health records to app-based interventions. The recent emergence of large…

We investigate the role of large language models (LLMs) in supporting mental health by analyzing Reddit posts and comments about mental health conversations with ChatGPT. Our findings reveal that users value ChatGPT as a safe,…

Human-Computer Interaction · Computer Science 2025-10-28 Kyuha Jung , Gyuho Lee , Yuanhui Huang , Yunan Chen

Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains…

Artificial Intelligence · Computer Science 2024-08-22 Yining Hua , Hongbin Na , Zehan Li , Fenglin Liu , Xiao Fang , David Clifton , John Torous

The global mental health crisis is looming with a rapid increase in mental disorders, limited resources, and the social stigma of seeking treatment. As the field of artificial intelligence (AI) has witnessed significant advancements in…

Computation and Language · Computer Science 2023-11-27 Neo Christopher Chung , George Dyer , Lennart Brocki

Large language models (LLMs) have offered new opportunities for emotional support, and recent work has shown that they can produce empathic responses to people in distress. However, long-term mental well-being requires emotional…

Computation and Language · Computer Science 2024-08-09 Hongli Zhan , Allen Zheng , Yoon Kyung Lee , Jina Suh , Junyi Jessy Li , Desmond C. Ong

Objectieve:This review aims to deliver a comprehensive analysis of Large Language Models (LLMs) utilization in mental health care, evaluating their effectiveness, identifying challenges, and exploring their potential for future application.…

Large language models (LLMs) are already being piloted for clinical use in hospital systems like NYU Langone, Dana-Farber and the NHS. A proposed deployment use case is psychotherapy, where a LLM-powered chatbot can treat a patient…

Computation and Language · Computer Science 2024-10-10 Saadia Gabriel , Isha Puri , Xuhai Xu , Matteo Malgaroli , Marzyeh Ghassemi

Large Language Models (LLMs) have achieved remarkable success across a wide array of tasks. Due to the impressive planning and reasoning abilities of LLMs, they have been used as autonomous agents to do many tasks automatically. Recently,…

Computation and Language · Computer Science 2024-04-22 Taicheng Guo , Xiuying Chen , Yaqi Wang , Ruidi Chang , Shichao Pei , Nitesh V. Chawla , Olaf Wiest , Xiangliang Zhang

Large Language Models (LLMs) are transforming mental health care by enhancing accessibility, personalization, and efficiency in therapeutic interventions. These AI-driven tools empower mental health professionals with real-time support,…

Computers and Society · Computer Science 2025-01-22 Hari Mohan Pandey

In response to the increasing mental health challenges faced by college students, we sought to understand their perspectives on how AI applications, particularly Large Language Models (LLMs), can be leveraged to enhance their mental…

Human-Computer Interaction · Computer Science 2024-09-27 Owen Xingjian Zhang , Shuyao Zhou , Jiayi Geng , Yuhan Liu , Sunny Xun Liu

Despite the increasing use of large language models (LLMs) in everyday life among neurodivergent individuals, our knowledge of how they engage with, and perceive LLMs remains limited. In this study, we investigate how neurodivergent…

Human-Computer Interaction · Computer Science 2024-10-10 Buse Carik , Kaike Ping , Xiaohan Ding , Eugenia H. Rho

Simulations, although powerful in accurately replicating real-world systems, often remain inaccessible to non-technical users due to their complexity. Conversely, large language models (LLMs) provide intuitive, language-based interactions…

Computation and Language · Computer Science 2025-05-22 Jacob Kleiman , Kevin Frank , Joseph Voyles , Sindy Campagna
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