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The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

Quantitative Methods · Quantitative Biology 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

In many use-cases, information is stored in text but not available in structured data. However, extracting data from natural language text to precisely fit a schema, and thus enable querying, is a challenging task. With the rise of…

Databases · Computer Science 2023-10-26 Mohammed Saeed , Nicola De Cao , Paolo Papotti

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

This article analyzes the use of Large Language Models (LLMs) as support for the conceptual modeling of relational databases through the automatic generation of Entity-Relationship (ER) diagrams from natural language requirements. The…

Artificial Intelligence · Computer Science 2026-05-13 Arthur F. Siqueira , Carlos D. S. Nogueira , Eduarda Farias , Claudio E. C. Campelo , Júlia Menezes

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

We propose leveraging Large Language Models (LLMs) as an interaction layer for medical visualization systems. In domains like healthcare, where users must navigate high-dimensional, coded, and heterogeneous datasets, LLM-generated queries…

Human-Computer Interaction · Computer Science 2025-09-12 Ambre Assor , Hyeon Jeon , Sungbok Shin , Jean-Daniel Fekete

With the exponential increase in online scientific literature, identifying reliable domain-specific data has become increasingly important but also very challenging. Manual data collection and filtering for domain-specific scientific…

Information Retrieval · Computer Science 2026-03-10 Nikita Gautam , Doina Caragea , Ignacio Ciampitti , Federico Gomez

Large language models (LLMs) excel in many natural language processing (NLP) tasks. However, since LLMs can only incorporate new knowledge through training or supervised fine-tuning processes, they are unsuitable for applications that…

Databases · Computer Science 2024-07-23 Zongyue Qin , Chen Luo , Zhengyang Wang , Haoming Jiang , Yizhou Sun

Large language models (LLMs) are advancing rapidly. Such models have demonstrated strong capabilities in learning from large-scale (unstructured) text data and answering user queries. Users do not need to be experts in structured query…

Databases · Computer Science 2023-10-02 Jianzhong Qi , Zuqing Li , Egemen Tanin

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

Digital Libraries · Computer Science 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma

Generating accurate SQL from users' natural language questions (text-to-SQL) remains a long-standing challenge due to the complexities involved in user question understanding, database schema comprehension, and SQL generation. Traditional…

Computation and Language · Computer Science 2025-11-25 Zijin Hong , Zheng Yuan , Qinggang Zhang , Hao Chen , Junnan Dong , Feiran Huang , Xiao Huang

The evolution of Large Language Models (LLMs) has showcased remarkable capacities for logical reasoning and natural language comprehension. These capabilities can be leveraged in solutions that semantically and textually model complex…

Human-Computer Interaction · Computer Science 2024-04-17 Syed Mekael Wasti , Ken Q. Pu , Ali Neshati

A Language Model is a term that encompasses various types of models designed to understand and generate human communication. Large Language Models (LLMs) have gained significant attention due to their ability to process text with human-like…

Computation and Language · Computer Science 2024-06-12 Sylvio Barbon Junior , Paolo Ceravolo , Sven Groppe , Mustafa Jarrar , Samira Maghool , Florence Sèdes , Soror Sahri , Maurice Van Keulen

The number of published scholarly articles is growing at a significant rate, making scholarly knowledge organization increasingly important. Various approaches have been proposed to organize scholarly information, including describing…

Digital Libraries · Computer Science 2025-01-22 Allard Oelen , Sören Auer

Multimodal search has become increasingly important in providing users with a natural and effective way to ex-press their search intentions. Images offer fine-grained details of the desired products, while text allows for easily…

Computer Vision and Pattern Recognition · Computer Science 2024-04-25 Oriol Barbany , Michael Huang , Xinliang Zhu , Arnab Dhua

Converting natural language (NL) questions into SQL queries, referred to as Text-to-SQL, has emerged as a pivotal technology for facilitating access to relational databases, especially for users without SQL knowledge. Recent progress in…

Computation and Language · Computer Science 2025-06-02 Yiming Huang , Jiyu Guo , Wenxin Mao , Cuiyun Gao , Peiyi Han , Chuanyi Liu , Qing Ling

Large language models (LLMs) are introducing a paradigm shift in molecular discovery by enabling text-guided interaction with chemical spaces through natural language, symbolic notations, with emerging extensions to incorporate multi-modal…

Machine Learning · Computer Science 2025-05-23 Ziqing Wang , Kexin Zhang , Zihan Zhao , Yibo Wen , Abhishek Pandey , Han Liu , Kaize Ding

The application of large language models (LLMs) in healthcare has gained significant attention due to their ability to process complex medical data and provide insights for clinical decision-making. These models have demonstrated…

Computer Vision and Pattern Recognition · Computer Science 2024-09-26 Amna Khalid , Ayma Khalid , Umar Khalid
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