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Depression has been the leading cause of mental-health illness worldwide. Major depressive disorder (MDD), is a common mental health disorder that affects both psychologically as well as physically which could lead to loss of lives. Due to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Anupama Ray , Siddharth Kumar , Rutvik Reddy , Prerana Mukherjee , Ritu Garg

Observational longitudinal studies are a common means to study treatment efficacy and safety in chronic mental illness. In many such studies, treatment changes may be initiated by either the patient or by their clinician and can thus vary…

Methodology · Statistics 2020-06-12 Zekun Xu , Eric Laber , Ana-Maria Staicu , Emanuel Severus

The recent shift to remote learning and work has aggravated long-standing problems, such as the problem of monitoring the mental health of individuals and the progress of students towards learning targets. We introduce a novel latent…

Applications · Statistics 2023-10-13 Minjeong Jeon , Michael Schweinberger

We introduce a novel Bayesian approach for jointly modeling longitudinal cardiovascular disease (CVD) risk factor trajectories, medication use, and time-to-events. Our methodology incorporates longitudinal risk factor trajectories into the…

Methodology · Statistics 2025-03-25 Zeynab Aghabazaz , Michael J Daniels , Donald M Lloyd-Jones , Juned Siddique

Joint models for longitudinal and survival data have gained a lot of attention in recent years, with the development of myriad extensions to the basic model, including those which allow for multivariate longitudinal data, competing risks…

Methodology · Statistics 2020-03-09 Katya Mauff , Ewout Steyerberg , Isabella Kardys , Eric Boersma , Dimitris Rizopoulos

The analysis of clinical questionnaire data comes with many inherent challenges. These challenges include the handling of data with missing fields, as well as the overall interpretation of a dataset with many fields of different scales and…

Machine Learning · Computer Science 2021-08-04 Connor J. McLaughlin , Efi G. Kokkotou , Jean A. King , Lisa A. Conboy , Ali Yousefi

Emotional coordination is a core property of human interaction that shapes how relational meaning is constructed in real time. While text-based affect inference has become increasingly feasible, prior approaches often treat sentiment as a…

We study identifying and estimating the causal effect of a treatment variable on a long-term outcome using data from an observational and an experimental domain. The observational data are subject to unobserved confounding. Furthermore,…

With the improvement of medical data capturing, vast amount of continuous patient monitoring data, e.g., electrocardiogram (ECG), real-time vital signs and medications, become available for clinical decision support at intensive care units…

Machine Learning · Computer Science 2018-07-25 Yanbo Xu , Siddharth Biswal , Shriprasad R Deshpande , Kevin O Maher , Jimeng Sun

Recurrent event time data arise in many studies, including biomedicine, public health, marketing, and social media analysis. High-dimensional recurrent event data involving many event types and observations have become prevalent with…

Methodology · Statistics 2025-04-02 Fangyi Chen , Yunxiao Chen , Zhiliang Ying , Kangjie Zhou

One of the most significant barriers to medication treatment is patients' non-adherence to a prescribed medication regimen. The extent of the impact of poor adherence on resulting health measures is often unknown, and typical analyses…

Applications · Statistics 2018-12-04 Luis F. Campos , Mark E. Glickman , Kristen B. Hunter

This paper generalises dynamic factor models for multidimensional dependent data. In doing so, it develops an interpretable technique to study complex information sources ranging from repeated surveys with a varying number of respondents to…

Econometrics · Economics 2023-01-31 Matteo Barigozzi , Filippo Pellegrino

Life course epidemiology of chronic diseases has been dominated so far by the environmental approach. Whether it focuses on early life exposures and events or later lifestyle behaviors, this approach assumes that previous life experiences…

Methodology · Statistics 2022-09-29 Marc Delord , Annastazia Learoyd , Abdel Douiri

The analysis of data arising from environmental health studies which collect a large number of measures of exposure can benefit from using latent variable models to summarize exposure information. However, difficulties with estimation of…

Applications · Statistics 2009-08-21 Brisa N. Sánchez , Esben Budtz-Jørgensen , Louise M. Ryan

This research develops a model-based LAtent Causal Socioeconomic Health (LACSH) index at the national level. Motivated by the need for a holistic national well-being index, we build upon the latent health factor index (LHFI) approach that…

Methodology · Statistics 2023-10-12 Swen Kuh , Grace S. Chiu , Anton H. Westveld

Evaluating and optimising human comfort within the built environment is challenging due to the large number of physiological, psychological and environmental variables that affect occupant comfort preference. Human perception could be…

Human-Computer Interaction · Computer Science 2020-10-30 Prageeth Jayathissa , Matias Quintana , Mahmoud Abdelrahman , Clayton Miller

Extensive bedside monitoring in Intensive Care Units (ICUs) has resulted in complex temporal data regarding patient physiology, which presents an upscale context for clinical data analysis. In the other hand, identifying the time-series…

Machine Learning · Computer Science 2023-08-25 Manel Mili , Asma Kerkeni , Asma Ben Abdallah , Mohamed Hedi Bedoui

The objective of this study is to introduce methodology for studying longitudinal claims data observed at the patient level, with inference on the heterogeneity of healthcare utilization behaviors within large healthcare systems such as…

Applications · Statistics 2016-03-04 Ross P. Hilton , Nicoleta Serban , Richard Y. Zheng

Electronic health records are being increasingly used in medical research to answer more relevant and detailed clinical questions; however, they pose new and significant methodological challenges. For instance, observation times are likely…

Analysis of longitudinal Electronic Health Record (EHR) data is an important goal for precision medicine. Difficulty in applying Machine Learning (ML) methods, either predictive or unsupervised, stems in part from the heterogeneity and…

Quantitative Methods · Quantitative Biology 2022-04-18 Alan D. Kaplan , Uttara Tipnis , Jean C. Beckham , Nathan A. Kimbrel , David W. Oslin , Benjamin H. McMahon