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Related papers: Biological Modelling with Nonlocal Advection Diffu…

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We provide a review of recent advancements in nonlocal continuous models for migration, mainly from the perspective of its involvement in embryonal development and cancer invasion. Particular emphasis is placed on spatial nonlocality…

Analysis of PDEs · Mathematics 2019-11-14 Li Chen , Kevin Painter , Christina Surulescu , Anna Zhigun

Animals use various processes to inform themselves about their environment and make decisions about how to move and form their territory. In some cases, populations inform themselves of competing groups through observations at distances,…

Populations and Evolution · Quantitative Biology 2022-11-17 Erin Ellefsen , Nancy Rodriguez

Non-local advection is a key process in a range of biological systems, from cells within individuals to the movement of whole organisms. Consequently, in recent years, there has been increasing attention on modelling non-local advection…

Analysis of PDEs · Mathematics 2021-06-14 Valeria Giunta , Thomas Hillen , Mark A. Lewis , Jonathan R. Potts

From tumour invasion to cell sorting and animal territoriality, many biological systems rely on nonlocal interactions that drive complex spatial organisation. Partial differential equations (PDEs) with nonlocal advection are increasingly…

Populations and Evolution · Quantitative Biology 2025-06-03 Valeria Giunta , Thomas Hillen , Mark A. Lewis , Jonathan R. Potts

Transport-dominated partial differential equation models have been used extensively over the past two decades to describe various collective migration phenomena in cell biology and ecology. To understand the behaviour of these models (and…

Numerical Analysis · Mathematics 2025-05-05 Johan Marguet , Raluca Eftimie , Alexei Lozinski

The inclusion of cognitive processes, such as perception, learning and memory, are inevitable in mechanistic animal movement modelling. Cognition is the unique feature that distinguishes animal movement from mere particle movement in…

Analysis of PDEs · Mathematics 2023-03-21 Hao Wang , Yurij Salmaniw

Throughout developmental biology and ecology, transport can be driven by nonlocal interactions. Examples include cells that migrate based on contact with pseudopodia extended from other cells, and animals that move based on their vision of…

Pattern Formation and Solitons · Physics 2023-07-07 Thomas Jun Jewell , Andrew L. Krause , Philip K. Maini , Eamonn A. Gaffney

Cell-cell adhesion plays a vital role in the development and maintenance of multicellular organisms. One of its functions is regulation of cell migration, such as occurs, e.g. during embryogenesis or in cancer. In this work, we develop a…

Tissues and Organs · Quantitative Biology 2024-03-08 Anna Zhigun , Mabel Lizzy Rajendran

We analyze a nonlocal PDE model describing the dynamics of adaptation of a phenotypically structured population, under the effects of mutation and selection, in a changing environment. Previous studies have analyzed the large-time behavior…

Analysis of PDEs · Mathematics 2020-09-25 Lionel Roques , Florian Patout , Olivier Bonnefon , Guillaume Martin

Nonlocal aggregation-diffusion models, when coupled with a spatial map, can capture cognitive and memory-based influences on animal movement and population-level patterns. In this work, we study a one-dimensional…

Analysis of PDEs · Mathematics 2025-03-17 Yurij Salmaniw , Di Liu , Junping Shi , Hao Wang

Nonlocality is important in realistic mathematical models of physical and biological systems when local models fail to capture the essential dynamics and interactions that occur over a range of distances. This review illustrates different…

Quantitative Methods · Quantitative Biology 2025-02-14 Swadesh Pal , Roderick Melnik

A slowly-varying or thin-layer multiscale assumption empowers macroscale understanding of many physical scenarios from dispersion in pipes and rivers, including beams, shells, and the modulation of nonlinear waves, to homogenisation of…

Dynamical Systems · Mathematics 2020-01-22 A. J. Roberts

Cell-cell adhesion is one the most fundamental mechanisms regulating collective cell migration during tissue development, homeostasis and repair, allowing cell populations to self-organize and eventually form and maintain complex tissue…

Cell Behavior · Quantitative Biology 2022-11-16 Carles Falcó , Ruth E. Baker , José A. Carrillo

Mathematical models describing the spatial spreading and invasion of populations of biological cells are often developed in a continuum modelling framework using reaction-diffusion equations. While continuum models based on linear diffusion…

Cellular Automata and Lattice Gases · Physics 2024-01-23 Matthew J Simpson , Keeley M Murphy , Scott W McCue , Pascal R Buenzli

Over the past decades, nonlocal models have been widely used to describe aggregation phenomena in biology, physics, engineering, and the social sciences. These are often derived as mean-field limits of attraction-repulsion agent-based…

Cell Behavior · Quantitative Biology 2025-05-14 Carles Falcó , Ruth E. Baker , José A. Carrillo

The role of memory and cognition in the movement of individuals (e.g. animals) within a population, is thought to play an important role in population dispersal. In response, there has been increasing interest in incorporating spatial…

Populations and Evolution · Quantitative Biology 2024-11-15 Yifei Li , Matthew J Simpson , Chuncheng Wang

Intracellular transport processes are essential to the healthy development of many organisms as well as more generally to healthy cellular function. The complex dynamics and interactions between protein molecules and filaments on different…

Dynamical Systems · Mathematics 2022-07-27 Maria-Veronica Ciocanel

We consider a model for the dynamics of active cells interacting with their quiescent counterparts under the influence of acidity characterized by proton concentration. The active cells perform nonlinear diffusion and infer proliferation or…

Analysis of PDEs · Mathematics 2025-11-04 Maria Eckardt , Christina Surulescu

Populations are heterogeneous, deviating in numerous ways. Phenotypic diversity refers to the range of traits or characteristics across a population, where for cells this could be the levels of signalling, movement and growth activity, etc.…

Cell Behavior · Quantitative Biology 2025-04-11 Tommaso Lorenzi , Kevin J Painter , Chiara Villa

Self-organisation of individuals within large collectives occurs throughout biology. Mathematical models can help elucidate the individual-level mechanisms behind these dynamics, but analytical tractability often comes at the cost of…

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