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In Multiple Instance Learning (MIL) problem for sequence data, the instances inside the bags are sequences. In some real world applications such as bioinformatics, comparing a random couple of sequences makes no sense. In fact, each…

Machine Learning · Computer Science 2020-06-15 Manel Zoghlami , Sabeur Aridhi , Mondher Maddouri , Engelbert Mephu Nguifo

Multiple Instance Learning (MIL) is a cornerstone approach in computational pathology (CPath) for generating clinically meaningful slide-level embeddings from gigapixel tissue images. However, MIL often struggles with small, weakly…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Daniel Shao , Richard J. Chen , Andrew H. Song , Joel Runevic , Ming Y. Lu , Tong Ding , Faisal Mahmood

In-Context Learning (ICL) has gained prominence due to its ability to perform tasks without requiring extensive training data and its robustness to noisy labels. A typical ICL workflow involves selecting localized examples relevant to a…

Information Retrieval · Computer Science 2025-05-07 Janak Kapuriya , Manit Kaushik , Debasis Ganguly , Sumit Bhatia

In-context learning (ICL) is an important paradigm for adapting large language models (LLMs) to new tasks, but the generalization behavior of ICL remains poorly understood. We investigate the inductive biases of ICL from the perspective of…

Computation and Language · Computer Science 2023-05-23 Chenglei Si , Dan Friedman , Nitish Joshi , Shi Feng , Danqi Chen , He He

Multiple Instance Learning (MIL) is widely used in analyzing histopathological Whole Slide Images (WSIs). However, existing MIL methods do not explicitly model the data distribution, and instead they only learn a bag-level or instance-level…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Linhao Qu , Xiaoyuan Luo , Shaolei Liu , Manning Wang , Zhijian Song

Multiple Instance Learning (MIL) and transformers are increasingly popular in histopathology Whole Slide Image (WSI) classification. However, unlike human pathologists who selectively observe specific regions of histopathology tissues under…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Conghao Xiong , Hao Chen , Joseph J. Y. Sung , Irwin King

Weakly Supervised Video Anomaly Detection (WSVAD) is challenging because the binary anomaly label is only given on the video level, but the output requires snippet-level predictions. So, Multiple Instance Learning (MIL) is prevailing in…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Hui Lv , Zhongqi Yue , Qianru Sun , Bin Luo , Zhen Cui , Hanwang Zhang

Segmenting tumors in histological images is vital for cancer diagnosis. While fully supervised models excel with pixel-level annotations, creating such annotations is labor-intensive and costly. Accurate histopathology image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yinsheng He , Xingyu Li , Roger J. Zemp

The quantity and the quality of the training labels are central problems in high-resolution land-cover mapping with machine-learning-based solutions. In this context, weak labels can be gathered in large quantities by leveraging on existing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Gianmarco Perantoni , Lorenzo Bruzzone

Multiple Instance Learning (MIL) is a weakly supervised paradigm that has been successfully applied to many different scientific areas and is particularly well suited to medical imaging. Probabilistic MIL methods, and more specifically…

Machine Learning · Computer Science 2024-03-25 F. M. Castro-Macías , P. Morales-Álvarez , Y. Wu , R. Molina , A. K. Katsaggelos

In the past few years, there has been an explosive surge in the use of machine learning (ML) techniques to address combinatorial optimization (CO) problems, especially mixed-integer linear programs (MILPs). Despite the achievements, the…

Machine Learning · Computer Science 2024-03-12 Zijie Geng , Xijun Li , Jie Wang , Xiao Li , Yongdong Zhang , Feng Wu

In Multiple Instance learning (MIL), weak labels are provided at the bag level with only presence/absence information known. However, there is a considerable gap in performance in comparison to a fully supervised model, limiting the…

Machine Learning · Computer Science 2021-03-22 Anxiang Zhang , Ankit Shah , Bhiksha Raj

This paper presents a weakly supervised image segmentation method that adopts tight bounding box annotations. It proposes generalized multiple instance learning (MIL) and smooth maximum approximation to integrate the bounding box tightness…

Computer Vision and Pattern Recognition · Computer Science 2021-10-25 Juan Wang , Bin Xia

Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology. Multi-instance learning (MIL) is a common solution for working with high resolution…

In computational pathology, weak supervision has become the standard for deep learning due to the gigapixel scale of WSIs and the scarcity of pixel-level annotations, with Multiple Instance Learning (MIL) established as the principal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Andreas Lolos , Theofilos Christodoulou , Aris L. Moustakas , Stergios Christodoulidis , Maria Vakalopoulou

In learning from aggregate labels, the training data consists of sets or "bags" of feature-vectors (instances) along with an aggregate label for each bag derived from the (usually {0,1}-valued) labels of its instances. In learning from…

Machine Learning · Computer Science 2024-11-12 Yukti Makhija , Rishi Saket

Whole slide image (WSI) classification is a critical task in computational pathology, requiring the processing of gigapixel-sized images, which is challenging for current deep-learning methods. Current state of the art methods are based on…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Machine learning models have become integral to many fields, but their reliability, defined as producing dependable, trustworthy, and domain-consistent predictions, remains a critical concern. Multiple Instance Learning (MIL) models…

Computer Vision and Pattern Recognition · Computer Science 2025-12-10 Hassan Keshvarikhojasteh , Marc Aubreville , Christof A. Bertram , Josien P. W. Pluim , Mitko Veta

In traditional multiple instance learning (MIL), both positive and negative bags are required to learn a prediction function. However, a high human cost is needed to know the label of each bag---positive or negative. Only positive bags…

Machine Learning · Computer Science 2016-03-17 Zhen Hu , Zhuyin Xue

An important task at the onset of a laparoscopic cholecystectomy (LC) operation is the inspection of gallbladder (GB) to evaluate the thickness of its wall, presence of inflammation and extent of fat. Difficulty in visualization of the GB…

Computer Vision and Pattern Recognition · Computer Science 2021-07-29 C. Loukas , A. Gazis , D. Schizas