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We propose a novel deep learning approach to nonparametric statistical inference for the conditional hazard function of survival time with right-censored data. We use a deep neural network (DNN) to approximate the logarithm of a conditional…

Methodology · Statistics 2024-10-24 Wen Su , Kin-Yat Liu , Guosheng Yin , Jian Huang , Xingqiu Zhao

Prognostic models in survival analysis are aimed at understanding the relationship between patients' covariates and the distribution of survival time. Traditionally, semi-parametric models, such as the Cox model, have been assumed. These…

Machine Learning · Statistics 2020-11-06 Denise Rava , Jelena Bradic

The Covid-19 pandemic has been one of the most devastating events in recent history, claiming the lives of more than 5 million people worldwide. Even with the worldwide distribution of vaccines, there is an apparent need for affordable,…

We describe a unified framework within which we can build survival models. The motivation for this work comes from a study on the prediction of relapse among breast cancer patients treated at the Curie Institute in Paris, France. Our focus…

Methodology · Statistics 2014-05-28 Cécile Chauvel , John O'Quigley

Loss Data Analytics is an interactive, online, freely available text. The idea behind the name Loss Data Analytics is to integrate classical loss data models from applied probability with modern analytic tools. In particular, we seek to…

Risk Management · Quantitative Finance 2018-08-22 Edward Frees

The classical approach to analyze time-to-event data, e.g. in clinical trials, is to fit Kaplan-Meier curves yielding the treatment effect as the hazard ratio between treatment groups. Afterwards commonly a log-rank test is performed in…

Methodology · Statistics 2020-09-16 Kathrin Möllenhoff , Achim Tresch

The COVID-19 pandemic has had a considerable impact on day-to-day life. Tackling the disease by providing the necessary resources to the affected is of paramount importance. However, estimation of the required resources is not a trivial…

Image and Video Processing · Electrical Eng. & Systems 2022-05-11 Sai Vidyaranya Nuthalapati , Marcela Vizcaychipi , Pallav Shah , Piotr Chudzik , Chee Hau Leow , Paria Yousefi , Ahmed Selim , Keiran Tait , Ben Irving

In this paper, we develop a new optimization framework for the least squares learning problem via fully connected neural networks or physics-informed neural networks. The gradient descent sometimes behaves inefficiently in deep learning…

Machine Learning · Computer Science 2025-05-01 Yaru Liu , Yiqi Gu , Michael K. Ng

We describe a new approach to estimating relative risks in time-to-event prediction problems with censored data in a fully parametric manner. Our approach does not require making strong assumptions of constant proportional hazard of the…

Machine Learning · Computer Science 2021-06-10 Chirag Nagpal , Xinyu Rachel Li , Artur Dubrawski

Applications of machine learning in healthcare often require working with time-to-event prediction tasks including prognostication of an adverse event, re-hospitalization or death. Such outcomes are typically subject to censoring due to…

Machine Learning · Computer Science 2022-08-04 Chirag Nagpal , Willa Potosnak , Artur Dubrawski

Survival analysis is a valuable tool for estimating the time until specific events, such as death or cancer recurrence, based on baseline observations. This is particularly useful in healthcare to prognostically predict clinically important…

Machine Learning · Computer Science 2024-01-11 Ahmed H. Shahin , An Zhao , Alexander C. Whitehead , Daniel C. Alexander , Joseph Jacob , David Barber

The COVID-19 pandemic has created unprecedented challenges worldwide. Strained healthcare providers make difficult decisions on patient triage, treatment and care management on a daily basis. Policy makers have imposed social distancing…

Regression has attracted immense interest lately due to its effectiveness in tasks like predicting values. And Regression is of widespread use in multiple fields such as Economics, Finance, Business, Biology and so on. While considerable…

Machine Learning · Computer Science 2021-04-27 Yunpeng Tai

We propose a novel method for predicting time-to-event in the presence of cure fractions based on flexible survivals models integrated into a deep neural network framework. Our approach allows for non-linear relationships and…

Machine Learning · Statistics 2024-11-11 Victor Medina-Olivares , Stefan Lessmann , Nadja Klein

Prediction of survival for cancer patients is an open area of research. However, many of these studies focus on datasets with a large number of patients. We present a novel method that is specifically designed to address the challenge of…

Machine Learning · Computer Science 2015-09-30 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

The goal of lifetime clustering is to develop an inductive model that maps subjects into $K$ clusters according to their underlying (unobserved) lifetime distribution. We introduce a neural-network based lifetime clustering model that can…

Machine Learning · Computer Science 2019-10-03 S Chandra Mouli , Leonardo Teixeira , Jennifer Neville , Bruno Ribeiro

Deep neural networks (DNNs) are powerful learning machines that have enabled breakthroughs in several domains. In this work, we introduce a new retrospective loss to improve the training of deep neural network models by utilizing the prior…

Computer Vision and Pattern Recognition · Computer Science 2020-06-25 Surgan Jandial , Ayush Chopra , Mausoom Sarkar , Piyush Gupta , Balaji Krishnamurthy , Vineeth Balasubramanian

Advances in survival analysis have facilitated unprecedented flexibility in data modeling, yet there remains a lack of tools for graphically illustrating the influence of continuous covariates on predicted survival outcomes. We propose the…

Applications · Statistics 2024-01-15 Yushu Shi , Liangliang Zhang , Kim-Anh Do , Robert R. Jenq , Christine B. Peterson

Deep learning is pervasive in our daily life, including self-driving cars, virtual assistants, social network services, healthcare services, face recognition, etc. However, deep neural networks demand substantial compute resources during…

Symbolic regression searches for analytic expressions that accurately describe studied phenomena. The main attraction of this approach is that it returns an interpretable model that can be insightful to users. Historically, the majority of…