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Cell crawling requires the generation of intracellular forces by the cytoskeleton and their transmission to an extracellular substrate through specific adhesion molecules. Crawling cells show many features of excitable systems, such as…

Biological Physics · Physics 2020-06-02 Pierre Sens

We study the enzymatic degradation of an elastic fiber under tension using an an isotropic random-walk model, coupled with binding-unbinding reactions that weaken the fiber. The fiber is represented by a chain of elastic springs in series,…

Statistical Mechanics · Physics 2009-10-08 Ascânio D. Araújo , Arnab Majumdar , Harikrishnan Parame swaran , Béla Suki

Dislocation climb mobilities, assuming vacancy bulk diffusion, are derived and implemented in dislocation dynamics simulations to study the coarsening of vacancy prismatic loops in fcc metals. When loops cannot glide, the comparison of the…

Materials Science · Physics 2011-06-29 Botond Bakó , Emmanuel Clouet , Laurent Dupuy , Marc Blétry

The mechanical properties of collagen fibrils depend on the amount and the distribution of water molecules within the fibrils. Here, we use atomic force microscopy (AFM) to study the effect of hydration on the viscoelastic properties of…

Soft Condensed Matter · Physics 2019-10-03 Manuel R. Uhlig , Robert Magerle

Using discrete element simulations based on molecular dynamics, we investigate the mechanical behavior of sheared, dry, frictional granular media in the "dense" and "critical" regimes. We find that this behavior is partitioned between…

Soft Condensed Matter · Physics 2025-02-25 Aurélien Rigotti , Véronique Dansereau , Jérôme Weiss

Crosslinked semi-flexible and flexible filaments that are actively deformed by molecular motors occur in various natural settings, such as the ordered eukaryotic flagellum, and the disordered cytoskeleton. The deformation of these composite…

Biological Physics · Physics 2018-10-02 Arvind Gopinath , Raghunath Chelakkot , L. Mahadevan

Biopolymer networks are common in biological systems from the cytoskeleton of individual cells to collagen in the extracellular matrix. The mechanics of these systems under applied strain can be explained in some cases by a phase transition…

Soft Condensed Matter · Physics 2022-12-21 Sadjad Arzash , Abhinav Sharma , Fred C. MacKintosh

This paper examines the mechanical response of flexible fiber packings subject to triaxial compression. Short fibers yield in a manner similar to typical granular materials in which the deviatoric stress remains nearly constant with…

Soft Condensed Matter · Physics 2023-01-18 Yu Guo , Yanjie Li , Qingzhao Liu , Hanhui Jin , Dandan Xu , Carl Wassgren , Jennifer Curtis

Shearing transitions of multi-layer molecularly thin-film lubrication systems in variations of the film-substrate coupling strength and the load are studied by using a multiscale method. Three kinds of the interlayer slips found in…

Chemical Physics · Physics 2017-06-07 Zuo-Bing Wu , X. C. Zeng

Under compressive stress, rock ``damage'' in the form of tensile microcracks is coupled to internal slip on microscopic interfaces, such as preexisting cracks and grain boundaries. In order to characterise the contribution of slip to the…

Geophysics · Physics 2022-11-23 Nicolas Brantut , Léo Petit

In this paper we report, clarify and broaden various recent efforts to complement the chemistry-centered models of force generation in muscles by mechanics-centered models. The physical mechanisms of interest can be grouped into two…

Biological Physics · Physics 2018-06-26 Matthieu Caruel , Lev Truskinovsky

The influence of alternating shear orientation and strain amplitude of cyclic loading on yielding in amorphous solids is investigated using molecular dynamics simulations. The model glass is represented via a binary mixture that was rapidly…

Soft Condensed Matter · Physics 2020-12-08 Nikolai V. Priezjev

Past models of stress-strain response under cyclic loading mainly rely on macroscopic equations which consider microstructure evolution indirectly or simply discard microstructure information. Modern materials science, on the other hand,…

Materials Science · Physics 2018-08-31 Ronghai Wu , Michael Zaiser

Filamentous bio-materials such as fibrin or collagen networks exhibit an enormous stiffening of their elastic moduli upon large deformations. This pronounced nonlinear behavior stems from a significant separation between the stiffnesses…

Soft Condensed Matter · Physics 2019-05-21 Robbie Rens , Carlos Villarroel , Gustavo Düring , Edan Lerner

Elastomers that can sustain large reversible strain are essential components for stretchable electronics. The stretchability and mechanical robustness of unfilled elastomers can be enhanced by introducing easier-to-break cross-links, e.g.…

Soft Condensed Matter · Physics 2020-01-20 Yikai Yin , Nicolas Bertin , Yanming Wang , Zhenan Bao , Wei Cai

We present a theoretical framework for the linear and nonlinear visco-elastic properties of reversibly crosslinked networks of semiflexible polymers. In contrast to affine models where network strain couples to the polymer end-to-end…

Soft Condensed Matter · Physics 2016-07-06 Jan Plagge , Andreas Fischer , Claus Heussinger

In this paper, we model the mechanics of a collagen pair in the connective tissue extracellular matrix that exists in abundance throughout animals, including the human body. This connective tissue comprises repeated units of two main…

Biomolecules · Quantitative Biology 2009-02-11 Yue Chan , Grant M. Cox , Richard G. Haverkamp , James M. Hill

Amorphous materials driven away from equilibrium display a diverse repertoire of complex, history-dependent behaviors. One striking feature is a failure to return to equilibrium after an abrupt change in otherwise static external…

Soft Condensed Matter · Physics 2025-06-12 Dor Shohat , Paul Baconnier , Itamar Procaccia , Martin van Hecke , Yoav Lahini

Wrinkling, creasing and folding are frequent phenomena encountered in biological and man-made bilayers made by thin films bonded to thicker and softer substrates often containing fibers. Paradigmatic examples of the latter are the skin, the…

Soft Condensed Matter · Physics 2024-01-23 A. Mirandola , A. Cutolo , A. R. Carotenuto , N. Nguyen , L. Pocivavsek , M. Fraldi , L. Deseri

Type I collagen fibrils have circular cross sections with radii mostly distributed in between 50 and 100 nm and are characterized by an axial banding pattern with a period of 67 nm. The constituent long molecules of those fibrils, the…

Soft Condensed Matter · Physics 2013-10-28 Jean Charvolin , Jean-François Sadoc
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