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Learning the underlying patterns in data goes beyond instance-based generalization to external knowledge represented in structured graphs or networks. Deep learning that primarily constitutes neural computing stream in AI has shown…

Artificial Intelligence · Computer Science 2023-09-04 Ugur Kursuncu , Manas Gaur , Amit Sheth

We study the problem of learning representations of entities and relations in knowledge graphs for predicting missing links. The success of such a task heavily relies on the ability of modeling and inferring the patterns of (or between) the…

Machine Learning · Computer Science 2019-02-28 Zhiqing Sun , Zhi-Hong Deng , Jian-Yun Nie , Jian Tang

The importance of studying properties of networks is manifest in diverse fields ranging from biology, engineering, physics, chemistry, neuroscience, and medicine. The functionality of networks with regard to performance, throughput,…

Molecular Networks · Quantitative Biology 2015-03-27 Allen Tannenbaum , Chris Sander , Liangjia Zhu , Romeil Sandhu , Ivan Kolesov , Eduard Reznik , Yasin Senbabaoglu , Tryphon Georgiou

Understanding how small molecules perturb gene expression is essential for uncovering drug mechanisms, predicting off-target effects, and identifying repurposing opportunities. While prior deep learning frameworks have integrated multimodal…

Machine Learning · Computer Science 2026-01-01 Pascal Passigan , Kevin Zhu , Angelina Ning

Graph embedding methods aim at finding useful graph representations by mapping nodes to a low-dimensional vector space. It is a task with important downstream applications, such as link prediction, graph reconstruction, data visualization,…

Machine Learning · Computer Science 2022-09-13 Said Kerrache , Hafida Benhidour

In recent years, artificial intelligence has played an important role on accelerating the whole process of drug discovery. Various of molecular representation schemes of different modals (e.g. textual sequence or graph) are developed. By…

Machine Learning · Computer Science 2022-11-28 Tianyu Wu , Yang Tang , Qiyu Sun , Luolin Xiong

Graph matching can be formalized as a combinatorial optimization problem, where there are corresponding relationships between pairs of nodes that can be represented as edges. This problem becomes challenging when there are potential…

Computer Vision and Pattern Recognition · Computer Science 2023-01-06 Dongdong Chen , Yuxing Dai , Lichi Zhang , Zhihong Zhang

We propose a learning framework to find the representation of a robot's kinematic structure and motion embedding spaces using graph neural networks (GNN). Finding a compact and low-dimensional embedding space for complex phenomena is a key…

Robotics · Computer Science 2023-02-01 J. Taery Kim , Jeongeun Park , Sungjoon Choi , Sehoon Ha

The limits of molecular dynamics (MD) simulations of macromolecules are steadily pushed forward by the relentless developments of computer architectures and algorithms. This explosion in the number and extent (in size and time) of MD…

Graphs face challenges when dealing with massive datasets. They are essential tools for modeling interconnected data and often become computationally expensive. Graph embedding techniques, on the other hand, provide an efficient approach.…

Databases · Computer Science 2024-12-16 Plácido A Souza Neto

In this thesis, we study the problem of feature learning on heterogeneous knowledge graphs. These features can be used to perform tasks such as link prediction, classification and clustering on graphs. Knowledge graphs provide rich…

Machine Learning · Computer Science 2018-09-11 Sebastian Bischoff

The recent proliferation of knowledge graphs (KGs) coupled with incomplete or partial information, in the form of missing relations (links) between entities, has fueled a lot of research on knowledge base completion (also known as relation…

Machine Learning · Computer Science 2019-06-05 Deepak Nathani , Jatin Chauhan , Charu Sharma , Manohar Kaul

Graph embedding algorithms are used to efficiently represent (encode) a graph in a low-dimensional continuous vector space that preserves the most important properties of the graph. One aspect that is often overlooked is whether the graph…

Machine Learning · Computer Science 2020-01-31 Zekarias T. Kefato , Nasrullah Sheikh , Alberto Montresor

Geospatial Knowledge Graphs (GeoKGs) model geoentities (e.g., places and natural features) and spatial relationships in an interconnected manner, providing strong knowledge support for geographic applications, including data retrieval,…

Artificial Intelligence · Computer Science 2024-10-25 Lei Hu , Wenwen Li , Yunqiang Zhu

This paper proposes a discrete knowledge graph (KG) embedding (DKGE) method, which projects KG entities and relations into the Hamming space based on a computationally tractable discrete optimization algorithm, to solve the formidable…

Information Retrieval · Computer Science 2021-01-14 Yunqi Li , Shuyuan Xu , Bo Liu , Zuohui Fu , Shuchang Liu , Xu Chen , Yongfeng Zhang

Inductive representation learning on temporal heterogeneous graphs is crucial for scalable deep learning on heterogeneous information networks (HINs) which are time-varying, such as citation networks. However, most existing approaches are…

Machine Learning · Computer Science 2024-05-15 Chenglin Li , Yuanzhen Xie , Chenyun Yu , Lei Cheng , Bo Hu , Zang Li , Di Niu

Spatio-temporal graphs such as traffic networks or gene regulatory systems present challenges for the existing deep learning methods due to the complexity of structural changes over time. To address these issues, we introduce…

Machine Learning · Computer Science 2019-04-15 Felix L. Opolka , Aaron Solomon , Cătălina Cangea , Petar Veličković , Pietro Liò , R Devon Hjelm

Graph are a ubiquitous data representation, as they represent a flexible and compact representation. For instance, the 3D structure of RNA can be efficiently represented as $\textit{2.5D graphs}$, graphs whose nodes are nucleotides and…

Machine Learning · Computer Science 2021-09-21 Vincent Mallet , Carlos G. Oliver , William L. Hamilton

With the rising interest in graph representation learning, a variety of approaches have been proposed to effectively capture a graph's properties. While these approaches have improved performance in graph machine learning tasks compared to…

Machine Learning · Computer Science 2019-10-09 Antonia Gogoglou , C. Bayan Bruss , Keegan E. Hines

Graph neural networks (GNNs) have been used extensively for addressing problems in drug design and discovery. Both ligand and target molecules are represented as graphs with node and edge features encoding information about atomic elements…

Machine Learning · Computer Science 2021-10-14 Dhananjay Bhaskar , Jackson D. Grady , Michael A. Perlmutter , Smita Krishnaswamy