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We study optimal design problems for stationary diffusion involving one or more state equations and mixtures of an arbitrary number of anisotropic materials. Since such problems typically do not admit classical solutions, we adopt a…

Optimization and Control · Mathematics 2026-01-21 Matko Grbac , Ivan Ivec , Marko Vrdoljak

In this paper, we investigate periodic solutions of regime-switching jump diffusions. We first show the well-posedness of solutions to the SDEs corresponding to the hybrid system. Then, we derive the strong Feller property and…

Probability · Mathematics 2020-10-06 Xiao-Xia Guo , Wei Sun

Since its introduction in 1952, Turing's (pre-)pattern theory ("the chemical basis of morphogenesis") has been widely applied to a number of areas in developmental biology. The related pattern formation models normally comprise a system of…

Cell Behavior · Quantitative Biology 2020-10-28 Fiona R Macfarlane , Mark AJ Chaplain , Tommaso Lorenzi

Every mathematical model describing physical phenomena is an approximation to model reality, hence has its limitations. Depending on characteristic values of the variables in the model, different aspects of the model and, e.g.,…

Analysis of PDEs · Mathematics 2019-12-02 Björn Augner , Dieter Bothe

Consider a particle diffusing in a confined volume which is divided into two equal regions. In one region the diffusion coefficient is twice the value of the diffusion coefficient in the other region. Will the particle spend equal…

Dynamical Systems · Mathematics 2015-06-04 P. F. Tupper , Xin Yang

Local diffusion coefficients in disordered systems such as spin glass systems and living cells are highly heterogeneous and may change over time. Such a time-dependent and spatially heterogeneous environment results in irreproducibility of…

Statistical Mechanics · Physics 2016-12-21 Takuma Akimoto , Eiji Yamamoto

The fast algorithms in Fourier optics have invigorated multifunctional device design and advanced imaging technologies. However, the necessity for fast computations has led to limitations in the widely used conventional Fourier methods,…

Applied Physics · Physics 2024-06-25 Zhi Li , Xuhao Luo , Jing Wang , Xin Yuan , Dongdong Teng , Qiang Song , Huigao Duan

A simple manner to describe the diffusive relaxation of a colloidal fluid adsorbed in a porous medium is to model the porous medium as a set of spherical particles fixed in space at random positions with prescribed statistical structural…

Robustness of spatial pattern against perturbations is an indispensable property of developmental processes for organisms, which need to adapt to changing environments. Although specific mechanisms for this robustness have been extensively…

Adaptation and Self-Organizing Systems · Physics 2017-04-05 Tetsuhiro S. Hatakeyama , Kunihiko Kaneko

Diffusion models are typically trained using pointwise reconstruction objectives that are agnostic to the spectral and multi-scale structure of natural signals. We propose a loss-level spectral regularization framework that augments…

Machine Learning · Computer Science 2026-03-04 Satish Chandran , Nicolas Roque dos Santos , Yunshu Wu , Greg Ver Steeg , Evangelos Papalexakis

Most biochemical reactions in living cells rely on diffusive search for target molecules or regions in a heterogeneous overcrowded cytoplasmic medium. Rapid re-arrangements of the medium constantly change the effective diffusivity felt…

Statistical Mechanics · Physics 2019-11-13 Yann Lanoiselée , Nicolas Moutal , Denis S. Grebenkov

In this paper, we employ an finite volume method (FVM) based on the heterogenous multiscale method (HMM), for the multiscale convection-diffusion-reaction problem. The optimal order convergence rate in H^1-norm is given for periodic medias.

Numerical Analysis · Mathematics 2015-12-22 Tao Yu , Haitao Cao

Diffusion models, a powerful and universal generative AI technology, have achieved tremendous success in computer vision, audio, reinforcement learning, and computational biology. In these applications, diffusion models provide flexible…

Machine Learning · Computer Science 2024-04-12 Minshuo Chen , Song Mei , Jianqing Fan , Mengdi Wang

In this paper a new integral equation solution to the elastic-plastic problem of functionally graded bars under torsional loading is presented. The formulation is general in the sense that it can be applied to an arbitrary cross-section…

Numerical Analysis · Mathematics 2017-05-30 George C. Tsiatas , Nick G. Babouskos

Fractional equations have become the model of choice in several applications where heterogeneities at the microstructure result in anomalous diffusive behavior at the macroscale. In this work we introduce a new fractional operator…

Numerical Analysis · Mathematics 2021-01-29 Marta D'Elia , Christian Glusa

Chemically-active colloids modify the concentration of chemical solutes surrounding them in order to self-propel. In doing so, they generate long-ranged hydrodynamic flows and chemical gradients that modify the trajectories of other…

Fluid Dynamics · Physics 2021-11-29 Francisco Rojas-Perez , Blaise Delmotte , Sebastien Michelin

Diffusion models have emerged as powerful tools for molecular generation, particularly in the context of 3D molecular structures. Inspired by non-equilibrium statistical physics, these models can generate 3D molecular structures with…

Chemical Physics · Physics 2025-05-16 Amira Alakhdar , Barnabas Poczos , Newell Washburn

Diffusion Models are probabilistic models that create realistic samples by simulating the diffusion process, gradually adding and removing noise from data. These models have gained popularity in domains such as image processing, speech…

Computer Vision and Pattern Recognition · Computer Science 2024-08-21 Md Manjurul Ahsan , Shivakumar Raman , Yingtao Liu , Zahed Siddique

The effect of introducing a spatial heterogeneity into an explosive medium is studied computationally by examining the detonation velocity near the limit to propagation in a thin explosive layer. The explosive system studied is an ideal gas…

Fluid Dynamics · Physics 2014-06-05 Jianling Li , Xiaocheng Mi , Andrew J. Higgins

In recent years, AI-assisted drug design methods have been proposed to generate molecules given the pockets' structures of target proteins. Most of them are atom-level-based methods, which consider atoms as basic components and generate…

Biomolecules · Quantitative Biology 2024-03-19 Haitao Lin , Yufei Huang , Odin Zhang , Lirong Wu , Siyuan Li , Zhiyuan Chen , Stan Z. Li
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