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Predicting counterfactual outcomes in longitudinal data, where sequential treatment decisions heavily depend on evolving patient states, is critical yet notoriously challenging due to complex time-dependent confounding and inadequate…

Machine Learning · Statistics 2026-04-15 Farbod Alinezhad , Jianfei Cao , Gary J. Young , Brady Post

Recent developments in generative artificial intelligence (AI) rely on machine learning techniques such as deep learning and generative modeling to achieve state-of-the-art performance across wide-ranging domains. These methods' surprising…

Machine Learning · Statistics 2026-01-27 Gemma E. Moran , Bryon Aragam

Deformable shape representations, parameterized by deformations relative to a given template, have proven effective for improved image analysis tasks. However, their broader applicability is hindered by two major challenges. First, existing…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Tonmoy Hossain , Miaomiao Zhang

Estimating the individuals' potential response to varying treatment doses is crucial for decision-making in areas such as precision medicine and management science. Most recent studies predict counterfactual outcomes by learning a covariate…

Machine Learning · Computer Science 2024-03-22 Minqin Zhu , Anpeng Wu , Haoxuan Li , Ruoxuan Xiong , Bo Li , Xiaoqing Yang , Xuan Qin , Peng Zhen , Jiecheng Guo , Fei Wu , Kun Kuang

Causal representation learning (CRL) offers the promise of uncovering the underlying causal model by which observed data was generated, but the practical applicability of existing methods remains limited by the strong assumptions required…

Machine Learning · Computer Science 2026-01-30 Yuhang Liu , Zhen Zhang , Dong Gong , Erdun Gao , Biwei Huang , Mingming Gong , Anton van den Hengel , Kun Zhang , Javen Qinfeng Shi

This paper presents the first deep reinforcement learning (DRL) framework to estimate the optimal Dynamic Treatment Regimes from observational medical data. This framework is more flexible and adaptive for high dimensional action and state…

Artificial Intelligence · Computer Science 2018-01-30 Ning Liu , Ying Liu , Brent Logan , Zhiyuan Xu , Jian Tang , Yanzhi Wang

Individual treatment effect (ITE) estimation requires adjusting for the covariate shift between populations with different treatments, and deep representation learning has shown great promise in learning a balanced representation of…

Machine Learning · Computer Science 2023-12-19 Amirreza Kazemi , Martin Ester

Graph embedding (GE) methods embed nodes (and/or edges) in graph into a low-dimensional semantic space, and have shown its effectiveness in modeling multi-relational data. However, existing GE models are not practical in real-world…

Machine Learning · Computer Science 2020-11-25 Xiaoyu Kou , Yankai Lin , Shaobo Liu , Peng Li , Jie Zhou , Yan Zhang

Counterfactual prediction is about predicting outcome of the unobserved situation from the data. For example, given patient is on drug A, what would be the outcome if she switch to drug B. Most of existing works focus on modeling…

Machine Learning · Computer Science 2020-10-29 Yanbo Xu , Cao Xiao , Jimeng Sun

Predictive models trained on observational data often fail to generalise to the distributions they encounter when deployed, especially when the training data is a product of the system being optimised. Recommender systems are a canonical…

Machine Learning · Statistics 2026-05-27 Yorgos Felekis , Michael O'Riordan , Oriol Corcoll , Ciarán M. Gilligan-Lee

The electromagnetic inverse problem has long been a research hotspot. This study aims to reverse radar view angles in synthetic aperture radar (SAR) images given a target model. Nonetheless, the scarcity of SAR data, combined with the…

Machine Learning · Computer Science 2024-01-03 Yanni Wang , Hecheng Jia , Shilei Fu , Huiping Lin , Feng Xu

Estimating the counterfactual outcome of treatment is essential for decision-making in public health and clinical science, among others. Often, treatments are administered in a sequential, time-varying manner, leading to an exponentially…

Machine Learning · Statistics 2024-07-16 Shenghao Wu , Wenbin Zhou , Minshuo Chen , Shixiang Zhu

We propose a doubly robust inference method for causal effects of continuous treatment variables, under unconfoundedness and with nonparametric or high-dimensional nuisance functions. Our double debiased machine learning (DML) estimators…

Econometrics · Economics 2023-10-02 Kyle Colangelo , Ying-Ying Lee

Recent developments in causal inference have greatly shifted the interest from estimating the average treatment effect to the individual treatment effect. In this article, we improve the predictive accuracy of representation learning and…

Machine Learning · Statistics 2025-08-05 Yang Sun , Wenbin Lu , Yi-Hui Zhou

Causal inference is capable of estimating the treatment effect (i.e., the causal effect of treatment on the outcome) to benefit the decision making in various domains. One fundamental challenge in this research is that the treatment…

Machine Learning · Computer Science 2021-12-28 Qian Li , Zhichao Wang , Shaowu Liu , Gang Li , Guandong Xu

Measuring treatment effects in observational studies is challenging because of confounding bias. Confounding occurs when a variable affects both the treatment and the outcome. Traditional methods such as propensity score matching estimate…

Methodology · Statistics 2021-12-23 Bevan I. Smith , Charles Chimedza

Reinforcement Learning (RL) has shown great promise in domains like healthcare and robotics but often struggles with adoption due to its lack of interpretability. Counterfactual explanations, which address "what if" scenarios, provide a…

Machine Learning · Computer Science 2025-05-20 Shuyang Dong , Shangtong Zhang , Lu Feng

Unsupervised representation learning with variational inference relies heavily on independence assumptions over latent variables. Causal representation learning (CRL), however, argues that factors of variation in a dataset are, in fact,…

Machine Learning · Computer Science 2023-07-13 Avinash Kori , Pedro Sanchez , Konstantinos Vilouras , Ben Glocker , Sotirios A. Tsaftaris

Proximal causal learning is a promising framework for identifying the causal effect under the existence of unmeasured confounders. Within this framework, the doubly robust (DR) estimator was derived and has shown its effectiveness in…

Methodology · Statistics 2024-03-12 Yong Wu , Yanwei Fu , Shouyan Wang , Xinwei Sun

Estimating treatment effects from observational data is challenging due to two main reasons: (a) hidden confounding, and (b) covariate mismatch (control and treatment groups not having identical distributions). Long lines of works exist…

Machine Learning · Computer Science 2025-04-30 Praharsh Nanavati , Ranjitha Prasad , Karthikeyan Shanmugam