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Multilingual vision-language (V&L) pre-training has achieved remarkable progress in learning universal representations across different modalities and languages. In spite of recent success, there still remain challenges limiting further…

Computation and Language · Computer Science 2023-05-16 Chulun Zhou , Yunlong Liang , Fandong Meng , Jinan Xu , Jinsong Su , Jie Zhou

Medical vision-language pre-training methods mainly leverage the correspondence between paired medical images and radiological reports. Although multi-view spatial images and temporal sequences of image-report pairs are available in…

Artificial Intelligence · Computer Science 2024-05-31 Jinxia Yang , Bing Su , Wayne Xin Zhao , Ji-Rong Wen

Large models have demonstrated exceptional generalization capabilities in computer vision and natural language processing. Recent efforts have focused on enhancing these models with multimodal processing abilities. However, addressing the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Hao Sun , Yu Song

Medical contrastive vision-language pre-training (VLP) has demonstrated significant potential in improving performance on downstream tasks. Traditional approaches typically employ contrastive learning, treating paired image-report samples…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Phuoc-Nguyen Bui , Toan Duc Nguyen , Junghyun Bum , Duc-Tai Le , Hyunseung Choo

Recently, self-supervised vision transformers have attracted unprecedented attention for their impressive representation learning ability. However, the dominant method, contrastive learning, mainly relies on an instance discrimination…

Computer Vision and Pattern Recognition · Computer Science 2022-01-20 Luya Wang , Feng Liang , Yangguang Li , Honggang Zhang , Wanli Ouyang , Jing Shao

Vision-language foundation models have emerged as powerful general-purpose representation learners with strong potential for multimodal understanding, but their deterministic embeddings often fail to provide the reliability required for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Ahmad Elallaf , Yu Zhang , Yuktha Priya Masupalli , Jeong Yang , Young Lee , Zechun Cao , Gongbo Liang

Preserving maximal information is one of principles of designing self-supervised learning methodologies. To reach this goal, contrastive learning adopts an implicit way which is contrasting image pairs. However, we believe it is not fully…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Hong-Yu Zhou , Chixiang Lu , Sibei Yang , Xiaoguang Han , Yizhou Yu

Medical image registration is a fundamental task in medical image analysis, enabling the alignment of images from different modalities or time points. However, intensity inconsistencies and nonlinear tissue deformations pose significant…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Eytan Kats , Christoph Grossbroehmer , Ziad Al-Haj Hemidi , Fenja Falta , Wiebke Heyer , Mattias P. Heinrich

Effective protein representation learning is crucial for predicting protein functions. Traditional methods often pretrain protein language models on large, unlabeled amino acid sequences, followed by finetuning on labeled data. While…

Biomolecules · Quantitative Biology 2024-09-05 Jiangbin Zheng , Stan Z. Li

Generating multi-contrasts/modal MRI of the same anatomy enriches diagnostic information but is limited in practice due to excessive data acquisition time. In this paper, we propose a novel deep-learning model for joint reconstruction and…

Image and Video Processing · Electrical Eng. & Systems 2022-06-30 Wanyu Bian , Qingchao Zhang , Xiaojing Ye , Yunmei Chen

Large pre-trained vision-language models like CLIP have shown great potential in learning representations that are transferable across a wide range of downstream tasks. Different from the traditional representation learning that is based…

Computer Vision and Pattern Recognition · Computer Science 2022-10-07 Kaiyang Zhou , Jingkang Yang , Chen Change Loy , Ziwei Liu

Medical diagnosis requires the effective synthesis of visual manifestations and clinical metadata. However, existing methods often treat metadata as isolated tags, failing to exploit the rich semantic knowledge embedded in clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Yiqing Wang , Chunming He , Ming-Chen Lu , Mercy Pawar , Leslie Niziol , Maria Woodward , Sina Farsiu

The integration of different imaging modalities, such as structural, diffusion tensor, and functional magnetic resonance imaging, with deep learning models has yielded promising outcomes in discerning phenotypic characteristics and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Zhiyuan Li , Hailong Li , Anca L. Ralescu , Jonathan R. Dillman , Mekibib Altaye , Kim M. Cecil , Nehal A. Parikh , Lili He

Multi-modal generative AI systems, such as those combining vision and language, rely on contrastive pre-training to learn representations across different modalities. While their practical benefits are widely acknowledged, a rigorous…

Machine Learning · Computer Science 2025-10-22 Kazusato Oko , Licong Lin , Yuhang Cai , Song Mei

Weakly supervised vision-and-language pre-training (WVLP), which learns cross-modal representations with limited cross-modal supervision, has been shown to effectively reduce the data cost of pre-training while maintaining decent…

Computer Vision and Pattern Recognition · Computer Science 2023-05-26 Chi Chen , Peng Li , Maosong Sun , Yang Liu

Transformers have gained increasing popularity in a wide range of applications, including Natural Language Processing (NLP), Computer Vision and Speech Recognition, because of their powerful representational capacity. However, harnessing…

Recent multimodal models such as Contrastive Language-Image Pre-training (CLIP) have shown remarkable ability to align visual and linguistic representations. However, domains where small visual differences carry large semantic significance,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Hiroshi Sasaki

This paper presents Prototypical Contrastive Learning (PCL), an unsupervised representation learning method that addresses the fundamental limitations of instance-wise contrastive learning. PCL not only learns low-level features for the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Junnan Li , Pan Zhou , Caiming Xiong , Steven C. H. Hoi

Multimodal pre-training demonstrates strong generalization performance, but this paradigm is often impractical in domains where paired data are scarce. A promising alternative is post-hoc multimodal alignment, which aligns separately…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Shiwon Kim , Yu Rang Park

Recent approaches in literature have exploited the multi-modal information in documents (text, layout, image) to serve specific downstream document tasks. However, they are limited by their - (i) inability to learn cross-modal…

Computation and Language · Computer Science 2022-01-06 Subhojeet Pramanik , Shashank Mujumdar , Hima Patel