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Facial pose estimation refers to the task of predicting face orientation from a single RGB image. It is an important research topic with a wide range of applications in computer vision. Label distribution learning (LDL) based methods have…
Autism Spectrum Disorder (ASD) is a neuro-developmental syndrome resulting from alterations in the embryological brain before birth. This disorder distinguishes its patients by special socially restricted and repetitive behavior in addition…
Machine learning methods applied to complex biomedical data has enabled the construction of disease signatures of diagnostic/prognostic value. However, less attention has been given to understanding disease heterogeneity. Semi-supervised…
Automatic facial action unit (AU) recognition is a challenging task due to the scarcity of manual annotations. To alleviate this problem, a large amount of efforts has been dedicated to exploiting various methods which leverage numerous…
Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. The progression and severity of MS varies by individual, but it is generally a disabling disease. Although medications have been developed to…
Machine Learning (ML) is used to tackle various tasks, such as disease classification and prediction. The effectiveness of ML models relies heavily on having large amounts of complete data. However, healthcare data is often limited or…
The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer's disease (AD) is clinically relevant, and may above all have a significant impact on accelerate the development of new treatments. In this…
The analysis of speech in individuals with amyotrophic lateral sclerosis is a powerful tool to support clinicians in the assessment of bulbar dysfunction. However, current methods used in clinical practice consist of subjective evaluations…
Acute aortic syndrome (AAS) is a group of life threatening conditions of the aorta. We have developed an end-to-end automatic approach to detect AAS in computed tomography (CT) images. Our approach consists of two steps. At first, we…
Cognitive decline is a sign of Alzheimer's disease (AD), and there is evidence that tracking a person's eye movement, using eye tracking devices, can be used for the automatic identification of early signs of cognitive decline. However,…
Early detection of skin cancers like melanoma is crucial to ensure high chances of survival for patients. Clinical application of Deep Learning (DL)-based Decision Support Systems (DSS) for skin cancer screening has the potential to improve…
While facial biometrics has been widely used for identification purpose, it has recently been researched as medical biometrics for a range of diseases. In this chapter, we investigate the facial landmark detection for atypical 3D facial…
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by motor neuron degeneration, with alterations in neural excitability serving as key indicators. Recent advancements in induced pluripotent stem cell…
Sepsis is a life threatening medical condition that occurs when the body has an extreme response to infection, leading to widespread inflammation, organ failure, and potentially death. Because sepsis can worsen rapidly, early detection is…
Craniofacial anomalies indicate early developmental disturbances and are usually linked to many genetic syndromes. Early diagnosis is critical, yet ultrasound (US) examinations often fail to identify these features. This study presents an…
Diagnosis based on medical images, such as X-ray images, often involves manual annotation of anatomical keypoints. However, this process involves significant human efforts and can thus be a bottleneck in the diagnostic process. To fully…
Aortic stenosis (AS) is a degenerative valve condition that causes substantial morbidity and mortality. This condition is under-diagnosed and under-treated. In clinical practice, AS is diagnosed with expert review of transthoracic…
This work describes an automatic methodology to discriminate between individuals with the genetic disorder Pitt-Hopkins syndrome (PTHS), and healthy individuals. As input data, the methodology accepts unconstrained frontal facial…
Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…
The most common reason for spinal surgery in elderly patients is lumbar spinal stenosis(LSS). For LSS, treatment decisions based on clinical and radiological information as well as personal experience of the surgeon shows large variance.…