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LLM routing aims to select the most appropriate model for each query, balancing competing performance metrics such as accuracy and cost across a pool of language models. Prior approaches typically adopt a decoupled strategy, where the…

Artificial Intelligence · Computer Science 2026-01-05 Asterios Tsiourvas , Wei Sun , Georgia Perakis

As large language models (LLMs) become increasingly embedded in everyday applications, ensuring their alignment with the diverse preferences of individual users has become a critical challenge. Currently deployed approaches typically assume…

Machine Learning · Computer Science 2024-12-19 Katarzyna Kobalczyk , Claudio Fanconi , Hao Sun , Mihaela van der Schaar

The exploration-exploitation dilemma has been a central challenge in reinforcement learning (RL) with complex model classes. In this paper, we propose a new algorithm, Monotonic Q-Learning with Upper Confidence Bound (MQL-UCB) for RL with…

Machine Learning · Computer Science 2025-10-06 Heyang Zhao , Jiafan He , Quanquan Gu

In this paper, we consider combinatorial reinforcement learning with preference feedback, where a learning agent sequentially offers an action--an assortment of multiple items to--a user, whose preference feedback follows a multinomial…

Machine Learning · Statistics 2025-06-06 Joongkyu Lee , Min-hwan Oh

Reinforcement learning is a popular method of finding optimal solutions to complex problems. Algorithms like Q-learning excel at learning to solve stochastic problems without a model of their environment. However, they take longer to solve…

Artificial Intelligence · Computer Science 2024-04-25 Jan Diekhoff , Jörn Fischer

Dynamic treatment regimes operationalize the clinical decision process as a sequence of functions, one for each clinical decision, where each function takes as input up-to-date patient information and gives as output a single recommended…

Methodology · Statistics 2012-08-08 Eric B. Laber , Daniel J. Lizotte , Bradley Ferguson

This work studies knowledge distillation (KD) for large language models (LLMs) through preference optimization. We propose a reward-guided imitation learning framework for sequential KD, formulating a min-max optimization problem between…

Machine Learning · Computer Science 2025-05-27 Chen Jia

Where performance comparison of healthcare providers is of interest, characteristics of both patients and the health condition of interest must be balanced across providers for a fair comparison. This is unlikely to be feasible within…

Methodology · Statistics 2019-09-04 Wendy J. Harrison , Paul D. Baxter , Mark S. Gilthorpe

Automated anesthesia promises to enable more precise and personalized anesthetic administration and free anesthesiologists from repetitive tasks, allowing them to focus on the most critical aspects of a patient's surgical care. Current…

Machine Learning · Computer Science 2023-11-14 Xiuding Cai , Jiao Chen , Yaoyao Zhu , Beimin Wang , Yu Yao

As LLMs become capable of complex tasks, there is growing potential for personalized interactions tailored to the subtle and idiosyncratic preferences of the user. We present a public benchmark, PersonalLLM, focusing on adapting LLMs to…

Machine Learning · Computer Science 2025-02-25 Thomas P. Zollo , Andrew Wei Tung Siah , Naimeng Ye , Ang Li , Hongseok Namkoong

While Reinforcement Learning from Human Feedback (RLHF) is widely used to align Large Language Models (LLMs) with human preferences, it typically assumes homogeneous preferences across users, overlooking diverse human values and minority…

Computation and Language · Computer Science 2025-10-28 Yijiang River Dong , Tiancheng Hu , Yinhong Liu , Ahmet Üstün , Nigel Collier

This paper explores the application of a reinforcement learning (RL) framework using the Q-Learning algorithm to enhance dynamic pricing strategies in the retail sector. Unlike traditional pricing methods, which often rely on static demand…

Machine Learning · Computer Science 2024-11-28 Mohit Apte , Ketan Kale , Pranav Datar , Pratiksha Deshmukh

Off-policy, value-based reinforcement learning methods such as Q-learning are appealing because they can learn from arbitrary experience, including data collected by older policies or other agents. In practice, however, bootstrapping makes…

Artificial Intelligence · Computer Science 2026-05-12 Armaan A. Abraham , Lucy Xiaoyang Shi , Chelsea Finn

Personalization is becoming indispensable for LLMs to align with individual user preferences and needs. Yet current approaches are often computationally expensive, data-intensive, susceptible to catastrophic forgetting, and prone to…

Computation and Language · Computer Science 2025-12-16 Baixiang Huang , Limeng Cui , Jiapeng Liu , Haoran Wang , Jiawei Xu , Zhuiyue Tan , Yutong Chen , Chen Luo , Yi Liu , Kai Shu

We present an approach called Q-probing to adapt a pre-trained language model to maximize a task-specific reward function. At a high level, Q-probing sits between heavier approaches such as finetuning and lighter approaches such as few shot…

Machine Learning · Computer Science 2024-06-04 Kenneth Li , Samy Jelassi , Hugh Zhang , Sham Kakade , Martin Wattenberg , David Brandfonbrener

Diagnostic testing provides a unique setting for studying and developing tools in classification theory. In such contexts, the concept of prevalence, i.e. the number of individuals with a given condition, is fundamental, both as an inherent…

Dynamical systems arise in a wide variety of mathematical models from science and engineering. A common challenge is to quantify uncertainties on model inputs (parameters) that correspond to a quantitative characterization of uncertainties…

Numerical Analysis · Mathematics 2021-07-19 Steven Mattis , Kyle Robert Steffen , Troy Butler , Clint N. Dawson , Donald Estep

A commonly used heuristic in RL is experience replay (e.g.~\citet{lin1993reinforcement, mnih2015human}), in which a learner stores and re-uses past trajectories as if they were sampled online. In this work, we initiate a rigorous study of…

Machine Learning · Computer Science 2021-12-09 Liran Szlak , Ohad Shamir

Longitudinal biomedical studies play a vital role in tracking disease progression, treatment response, and the emergence of resistance mechanisms, particularly in complex disorders such as cancer and neurodegenerative diseases. However, the…

Quantitative Methods · Quantitative Biology 2025-04-28 Maria Demidik , Filippo Utro , Alexey Galda , Karl Jansen , Daniel Blankenberg , Laxmi Parida

Stabilized dynamic treatment regimes are sequential decision rules for individual patients that not only adaptive throughout the disease progression but also remain consistent over time in format. The estimation of stabilized dynamic…

Methodology · Statistics 2019-03-05 Ying-Qi Zhao , Ruoqing Zhu , Guanhua Chen , Yingye Zheng