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Related papers: SLPD: Slide-level Prototypical Distillation for WS…

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Deploying high-performing 3D medical image segmenters (e.g., nnU-Net) is often limited by memory footprint and inference latency. Compression is therefore necessary, but compact 3D encoders tend to lose fine structural cues (small lesions…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Mengchen Fan , Baocheng Geng , Xi Xiao , Tianyang Wang , Siyuan Mei , Pulin Che , Xiaoqian Jiang , Qizhen Lan

Cancer subtyping is one of the most challenging tasks in digital pathology, where Multiple Instance Learning (MIL) by processing gigapixel whole slide images (WSIs) has been in the spotlight of recent research. However, MIL approaches do…

Whole slide images (WSI) are microscopy images of stained tissue slides routinely prepared for diagnosis and treatment selection in medical practice. WSI are very large (gigapixel size) and complex (made of up to millions of cells). The…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Tristan Lazard , Marvin Lerousseau , Etienne Decencière , Thomas Walter

Self-supervised learning (SSL) has made remarkable progress in visual representation learning. Some studies combine SSL with knowledge distillation (SSL-KD) to boost the representation learning performance of small models. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Kaiyou Song , Jin Xie , Shan Zhang , Zimeng Luo

Reinforcement learning (RL) has been widely used to train LLM agents for multi-turn interactive tasks, but its sample efficiency is severely limited by sparse rewards and long horizons. On-policy self-distillation (OPSD) alleviates this by…

Machine Learning · Computer Science 2026-04-14 Hao Wang , Guozhi Wang , Han Xiao , Yufeng Zhou , Yue Pan , Jichao Wang , Ke Xu , Yafei Wen , Xiaohu Ruan , Xiaoxin Chen , Honggang Qi

Recent advances in vision-language models (VLMs) have shown remarkable potential in bridging visual and textual modalities. In computational pathology, domain-specific VLMs, which are pre-trained on extensive histopathology image-text…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Anh Tien Nguyen , Keunho Byeon , Kyungeun Kim , Jin Tae Kwak

Multiple instance learning is an ideal mode of analysis for histopathology data, where vast whole slide images are typically annotated with a single global label. In such cases, a whole slide image is modelled as a collection of tissue…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Leo Fillioux , Joseph Boyd , Maria Vakalopoulou , Paul-Henry Cournède , Stergios Christodoulidis

Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…

In the field of computational histopathology, both whole slide images (WSIs) and diagnostic captions provide valuable insights for making diagnostic decisions. However, aligning WSIs with diagnostic captions presents a significant…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Qifeng Zhou , Wenliang Zhong , Yuzhi Guo , Michael Xiao , Hehuan Ma , Junzhou Huang

Existing CNNs-Based RGB-D salient object detection (SOD) networks are all required to be pretrained on the ImageNet to learn the hierarchy features which helps provide a good initialization. However, the collection and annotation of…

Computer Vision and Pattern Recognition · Computer Science 2021-12-06 Xiaoqi Zhao , Youwei Pang , Lihe Zhang , Huchuan Lu , Xiang Ruan

Local field potentials (LFPs) can be routinely recorded alongside spiking activity in intracortical neural experiments, measure a larger complementary spatiotemporal scale of brain activity for scientific inquiry, and can offer practical…

Machine Learning · Computer Science 2025-12-16 Eray Erturk , Saba Hashemi , Maryam M. Shanechi

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi

This paper studies the problem of Line Segment Detection (LSD) for the characterization of line geometry in images, with the aim of learning a domain-agnostic robust LSD model that works well for any natural images. With the focus of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Zeran Ke , Bin Tan , Xianwei Zheng , Yujun Shen , Tianfu Wu , Nan Xue

The Semantic Layered Embedding Diffusion (SLED) mechanism redefines the representation of hierarchical semantics within transformer-based architectures, enabling enhanced contextual consistency across a wide array of linguistic tasks. By…

Computation and Language · Computer Science 2025-03-26 Irin Kabakum , Thomas Montgomery , Daniel Ravenwood , Genevieve Harrington

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

One of the main obstacles of adopting digital pathology is the challenge of efficient processing of hyperdimensional digitized biopsy samples, called whole slide images (WSIs). Exploiting deep learning and introducing compact WSI…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Azam Asilian Bidgoli , Shahryar Rahnamayan , Taher Dehkharghanian , Abtin Riasatian , H. R. Tizhoosh

Deep learning has achieved remarkable progress for visual recognition on large-scale balanced datasets but still performs poorly on real-world long-tailed data. Previous methods often adopt class re-balanced training strategies to…

Computer Vision and Pattern Recognition · Computer Science 2021-09-10 Tianhao Li , Limin Wang , Gangshan Wu

Multiple instance learning (MIL) has become a preferred method for gigapixel whole slide image (WSI) classification without requiring patch-level annotations. Current MIL research primarily relies on embedding-based approaches, which…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Bryan Wong , Sungrae Hong , Mun Yong Yi

Learning high-quality, self-supervised, visual representations is essential to advance the role of computer vision in biomedical microscopy and clinical medicine. Previous work has focused on self-supervised representation learning (SSL)…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Cheng Jiang , Xinhai Hou , Akhil Kondepudi , Asadur Chowdury , Christian W. Freudiger , Daniel A. Orringer , Honglak Lee , Todd C. Hollon

This paper demonstrates that spatial information can be used to learn interpretable representations in medical images using Self-Supervised Learning (SSL). Our proposed method, ISImed, is based on the observation that medical images exhibit…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Nabil Jabareen , Dongsheng Yuan , Sören Lukassen