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Although generative adversarial networks (GANs) have shown promise in medical imaging, they have four main limitations that impeded their utility: computational cost, data requirements, reliable evaluation measures, and training complexity.…

Deep Learning models are easily disturbed by variations in the input images that were not seen during training, resulting in unpredictable behaviours. Such Out-of-Distribution (OOD) images represent a significant challenge in the context of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Benjamin Lambert , Florence Forbes , Senan Doyle , Alan Tucholka , Michel Dojat

Deep neural networks have shown promising results in disease detection and classification using medical image data. However, they still suffer from the challenges of handling real-world scenarios especially reliably detecting…

Image and Video Processing · Electrical Eng. & Systems 2021-11-03 Muhammad Zaida , Shafaqat Ali , Mohsen Ali , Sarfaraz Hussein , Asma Saadia , Waqas Sultani

Deep Learning (DL) models tend to perform poorly when the data comes from a distribution different from the training one. In critical applications such as medical imaging, out-of-distribution (OOD) detection helps to identify such data…

Image and Video Processing · Electrical Eng. & Systems 2023-06-26 Daria Frolova , Anton Vasiliuk , Mikhail Belyaev , Boris Shirokikh

Computer-aided diagnostics has benefited from the development of deep learning-based computer vision techniques in these years. Traditional supervised deep learning methods assume that the test sample is drawn from the identical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Zesheng Hong , Yubiao Yue , Yubin Chen , Lele Cong , Huanjie Lin , Yuanmei Luo , Mini Han Wang , Weidong Wang , Jialong Xu , Xiaoqi Yang , Hechang Chen , Zhenzhang Li , Sihong Xie

Clinically deployed segmentation models are known to fail on data outside of their training distribution. As these models perform well on most cases, it is imperative to detect out-of-distribution (OOD) images at inference to protect…

Machine Learning · Computer Science 2023-10-23 McKell Woodland , Nihil Patel , Mais Al Taie , Joshua P. Yung , Tucker J. Netherton , Ankit B. Patel , Kristy K. Brock

Out-of-distribution (OOD) detection is essential for building reliable AI systems, as models that produce outputs for invalid inputs cannot be trusted. Although deep learning (DL) is often assumed to outperform traditional machine learning…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Jihyeon Baek , Seunghoon Lee , Gitaek Kwon , Doohyun Park

We present a principled approach for detecting out-of-distribution (OOD) and adversarial samples in deep neural networks. Our approach consists in modeling the outputs of the various layers (deep features) with parametric probability…

Machine Learning · Statistics 2019-09-27 Nilesh A. Ahuja , Ibrahima Ndiour , Trushant Kalyanpur , Omesh Tickoo

Deep neural networks have attained remarkable performance when applied to data that comes from the same distribution as that of the training set, but can significantly degrade otherwise. Therefore, detecting whether an example is…

Computer Vision and Pattern Recognition · Computer Science 2020-04-02 Yen-Chang Hsu , Yilin Shen , Hongxia Jin , Zsolt Kira

In the domain of machine learning, the assumption that training and test data share the same distribution is often violated in real-world scenarios, requiring effective out-of-distribution (OOD) detection. This paper presents a novel OOD…

Machine Learning · Computer Science 2025-02-25 Alessandro Canevaro , Julian Schmidt , Mohammad Sajad Marvi , Hang Yu , Georg Martius , Julian Jordan

Unsupervised Out-of-Distribution (OOD) detection consists in identifying anomalous regions in images leveraging only models trained on images of healthy anatomy. An established approach is to tokenize images and model the distribution of…

Computer Vision and Pattern Recognition · Computer Science 2023-08-04 Sergio Naval Marimont , Vasilis Siomos , Giacomo Tarroni

Out-of-distribution detection (OOD) is a pivotal task for real-world applications that trains models to identify samples that are distributionally different from the in-distribution (ID) data during testing. Recent advances in AI,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Chaohua Li , Enhao Zhang , Chuanxing Geng , Songcan Chen

Image classification models deployed in the real world may receive inputs outside the intended data distribution. For critical applications such as clinical decision making, it is important that a model can detect such out-of-distribution…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Christoph Berger , Magdalini Paschali , Ben Glocker , Konstantinos Kamnitsas

In a clinical setting it is essential that deployed image processing systems are robust to the full range of inputs they might encounter and, in particular, do not make confidently wrong predictions. The most popular approach to safe…

In this paper, we tackle the detection of out-of-distribution (OOD) objects in semantic segmentation. By analyzing the literature, we found that current methods are either accurate or fast but not both which limits their usability in real…

Computer Vision and Pattern Recognition · Computer Science 2021-08-04 Victor Besnier , Andrei Bursuc , David Picard , Alexandre Briot

Motivation: Deep learning models deployed for use on medical tasks can be equipped with Out-of-Distribution Detection (OoDD) methods in order to avoid erroneous predictions. However it is unclear which OoDD method should be used in…

Machine Learning · Computer Science 2020-08-06 Tianshi Cao , Chin-Wei Huang , David Yu-Tung Hui , Joseph Paul Cohen

Out-of-distribution (OOD) detection is crucial for safely deploying automated medical image analysis systems, as abnormal patterns in images could hamper their performance. However, OOD detection in medical imaging remains an open…

Image and Video Processing · Electrical Eng. & Systems 2025-09-18 Evi M. C. Huijben , Sina Amirrajab , Josien P. W. Pluim

Out-of-Distribution (OOD) detection is critical for safe deployment; however, existing detectors often struggle to generalize across datasets of varying scales and model architectures, and some can incur high computational costs in…

Machine Learning · Computer Science 2025-04-04 Litian Liu , Yao Qin

One of the challenges for neural networks in real-life applications is the overconfident errors these models make when the data is not from the original training distribution. Addressing this issue is known as Out-of-Distribution (OOD)…

Computer Vision and Pattern Recognition · Computer Science 2024-07-24 Sina Sharifi , Taha Entesari , Bardia Safaei , Vishal M. Patel , Mahyar Fazlyab

Out-of-distribution (OoD) detection is a natural downstream task for deep generative models, due to their ability to learn the input probability distribution. There are mainly two classes of approaches for OoD detection using deep…

Machine Learning · Computer Science 2019-07-11 Yujia Huang , Sihui Dai , Tan Nguyen , Richard G. Baraniuk , Anima Anandkumar
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