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Diffusion models have become a leading approach for high-fidelity medical image synthesis. However, most existing methods for 3D medical image generation rely on convolutional U-Net backbones within latent diffusion frameworks. While…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Marvin Seyfarth , Salman Ul Hassan Dar , Yannik Frisch , Philipp Wild , Norbert Frey , Florian André , Sandy Engelhardt

In the medical domain, acquiring large datasets is challenging due to both accessibility issues and stringent privacy regulations. Consequently, data availability and privacy protection are major obstacles to applying machine learning in…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Wenwu Tang , Khaled Seyam , Bin Yang

Despite the increasing use of deep learning in medical image segmentation, the limited availability of annotated training data remains a major challenge due to the time-consuming data acquisition and privacy regulations. In the context of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

We propose a multimodal latent diffusion model that jointly synthesizes volumetric magnetic resonance imaging (MRI) and tabular clinical data within a shared latent space via cross-attention. This approach enables coherent joint…

Image and Video Processing · Electrical Eng. & Systems 2026-05-11 Daniel Mensing , Jan Kapar , Jochen G. Hirsch , Matthias Günther , Horst Hahn , Marvin N. Wright

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Mainstream deep models for three-dimensional MRI synthesis are either cross-sectional or volumetric depending on the input. Cross-sectional models can decrease the model complexity, but they may lead to discontinuity artifacts. On the other…

Image and Video Processing · Electrical Eng. & Systems 2021-01-14 Muzaffer Özbey , Mahmut Yurt , Salman Ul Hassan Dar , Tolga Çukur

The generation of medical images presents significant challenges due to their high-resolution and three-dimensional nature. Existing methods often yield suboptimal performance in generating high-quality 3D medical images, and there is…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Haoshen Wang , Zhentao Liu , Kaicong Sun , Xiaodong Wang , Dinggang Shen , Zhiming Cui

MRI synthesis promises to mitigate the challenge of missing MRI modality in clinical practice. Diffusion model has emerged as an effective technique for image synthesis by modelling complex and variable data distributions. However, most…

Image and Video Processing · Electrical Eng. & Systems 2023-03-27 Lan Jiang , Ye Mao , Xi Chen , Xiangfeng Wang , Chao Li

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Magnetic Resonance Imaging (MRI) is a crucial diagnostic tool, but high-resolution scans are often slow and expensive due to extensive data acquisition requirements. Traditional MRI reconstruction methods aim to expedite this process by…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Emmanuelle Bourigault , Abdullah Hamdi , Amir Jamaludin

Multi-modal images play a crucial role in comprehensive evaluations in medical image analysis providing complementary information for identifying clinically important biomarkers. However, in clinical practice, acquiring multiple modalities…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jonghun Kim , Hyunjin Park

The work proposes a novel deep-learning framework for the synthesis of three-dimensional MRI volumes from corresponding 3D ultrasound images of the brain, leveraging a modified iteration of the Pix2Pix Generative Adversarial Network (GAN)…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Shubham Singh , Mrunal Bewoor , Ammar Ranapurwala , Satyam Rai , Sheetal Patil

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Multimodal medical images play a crucial role in the precise and comprehensive clinical diagnosis. Diffusion model is a powerful strategy to synthesize the required medical images. However, existing approaches still suffer from the problem…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Jiahua Xu , Dawei Zhou , Lei Hu , Zaiyi Liu , Nannan Wang , Xinbo Gao

Synthesized medical images have several important applications, e.g., as an intermedium in cross-modality image registration and as supplementary training samples to boost the generalization capability of a classifier. Especially,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Zizhao Zhang , Lin Yang , Yefeng Zheng

Diffusion probabilistic models have demonstrated significant potential in generating high-quality, realistic medical images, providing a promising solution to the persistent challenge of data scarcity in the medical field. Nevertheless,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Delin An , Chaoli Wang

The number of samples in structural brain MRI studies is often too small to properly train deep learning models. Generative models show promise in addressing this issue by effectively learning the data distribution and generating…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Wei Peng , Tian Xia , Fabio De Sousa Ribeiro , Tomas Bosschieter , Ehsan Adeli , Qingyu Zhao , Ben Glocker , Kilian M. Pohl

Despite significant progress in generative modelling, existing diffusion models often struggle to produce anatomically precise female pelvic images, limiting their application in gynaecological imaging, where data scarcity and patient…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Johanna P. Müller , Anika Knupfer , Pedro Blöss , Edoardo Berardi Vittur , Bernhard Kainz , Jana Hutter

Solving 3D medical inverse problems such as image restoration and reconstruction is crucial in modern medical field. However, the curse of dimensionality in 3D medical data leads mainstream volume-wise methods to suffer from high resource…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Jia He , Bonan Li , Ge Yang , Ziwen Liu

Temporal volume images with 3D+t (4D) information are often used in medical imaging to statistically analyze temporal dynamics or capture disease progression. Although deep-learning-based generative models for natural images have been…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Boah Kim , Jong Chul Ye
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