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Recruiting patients to participate in clinical trials can be challenging and time-consuming. Usually, participation in a clinical trial is initiated by a healthcare professional and proposed to the patient. Promoting clinical trials…

Computation and Language · Computer Science 2025-03-21 Mathilde Aguiar , Pierre Zweigenbaum , Nona Naderi

Machine learning (ML) has recently shown promising results in medical predictions using electronic health records (EHRs). However, since ML models typically have a limited capability in terms of input sizes, selecting specific medical…

Machine Learning · Computer Science 2024-07-23 Junu Kim , Chaeeun Shim , Bosco Seong Kyu Yang , Chami Im , Sung Yoon Lim , Han-Gil Jeong , Edward Choi

Retrieving relevant targets from an extremely large target set under computational limits is a common challenge for information retrieval and recommendation systems. Tree models, which formulate targets as leaves of a tree with trainable…

Machine Learning · Statistics 2020-06-30 Jingwei Zhuo , Ziru Xu , Wei Dai , Han Zhu , Han Li , Jian Xu , Kun Gai

Clinical decision support tools built on electronic health records often experience performance drift due to temporal population shifts, particularly when changes in the clinical environment initially affect only a subset of patients,…

Machine Learning · Computer Science 2025-12-16 Mengying Yan , Ziye Tian , Siqi Li , Nan Liu , Benjamin A. Goldstein , Molei Liu , Chuan Hong

The broad adoption of Electronic Health Records (EHR) has led to vast amounts of data being accumulated on a patient's history, diagnosis, prescriptions, and lab tests. Advances in recommender technologies have the potential to utilize this…

Information Retrieval · Computer Science 2020-09-01 Suman Bhoi , Lee Mong Li , Wynne Hsu

Deep Reinforcement Learning (DRL) has recently achieved significant advances in various domains. However, explaining the policy of RL agents still remains an open problem due to several factors, one being the complexity of explaining neural…

Machine Learning · Computer Science 2021-03-31 Zihan Ding , Pablo Hernandez-Leal , Gavin Weiguang Ding , Changjian Li , Ruitong Huang

The research explores the utilization of a deep learning model employing an attention mechanism in medical text mining. It targets the challenge of analyzing unstructured text information within medical data. This research seeks to enhance…

Computation and Language · Computer Science 2024-06-04 Lingxi Xiao , Muqing Li , Yinqiu Feng , Meiqi Wang , Ziyi Zhu , Zexi Chen

Missing data, inaccuracies in medication lists, and recording delays in electronic health records (EHR) are major limitations for target trial emulation (TTE), the process by which EHR data are used to retrospectively emulate a randomized…

Applications · Statistics 2025-01-16 Max Sunog , Colin Magdamo , Marie-Laure Charpignon , Mark Albers

The rapid expansion of electronic health record (EHR) systems has generated large volumes of unstructured clinical narratives that contain valuable information for disease identification, patient cohort discovery, and clinical decision…

Computation and Language · Computer Science 2026-03-17 Fariba Afrin Irany , Sampson Akwafuo

We propose an approach for learning optimal tree-based prescription policies directly from data, combining methods for counterfactual estimation from the causal inference literature with recent advances in training globally-optimal decision…

Machine Learning · Computer Science 2020-12-07 Maxime Amram , Jack Dunn , Ying Daisy Zhuo

AI-driven clinical text classification is vital for explainable automated retrieval of population-level health information. This work investigates whether human-based clinical rationales can serve as additional supervision to improve both…

Computation and Language · Computer Science 2025-07-30 Christoph Metzner , Shang Gao , Drahomira Herrmannova , Heidi A. Hanson

Tree-based machine learning models such as random forests, decision trees, and gradient boosted trees are the most popular non-linear predictive models used in practice today, yet comparatively little attention has been paid to explaining…

Decision trees are considered one of the most powerful tools for data classification. Accelerating the decision tree search is crucial for on-the-edge applications that have limited power and latency budget. In this paper, we propose a…

Hardware Architecture · Computer Science 2022-04-14 Mariam Rakka , Mohammed E. Fouda , Rouwaida Kanj , Fadi Kurdahi

Deep learning models have demonstrated superior performance in various healthcare applications. However, the major limitation of these deep models is usually the lack of high-quality training data due to the private and sensitive nature of…

Computation and Language · Computer Science 2022-11-15 Qiuhao Lu , Dejing Dou , Thien Huu Nguyen

Individualized treatment rules (ITRs) aim to optimize healthcare by tailoring treatment decisions to patient-specific characteristics. Existing methods typically rely on either interpretable but inflexible models or highly flexible…

Methodology · Statistics 2026-02-13 Yasin Khadem Charvadeh , Katherine S. Panageas , Yuan Chen

The rapid accumulation of Electronic Health Records (EHRs) has transformed healthcare by providing valuable data that enhance clinical predictions and diagnoses. While conventional machine learning models have proven effective, they often…

Clinical trial eligibility matching is a critical yet often labor-intensive and error-prone step in medical research, as it ensures that participants meet precise criteria for safe and reliable study outcomes. Recent advances in Natural…

Machine Learning · Computer Science 2025-03-04 Muhammad Talha Sharif , Abdul Rehman

Tree-based models have been successfully applied to a wide variety of tasks, including time series forecasting. They are increasingly in demand and widely accepted because of their comparatively high level of interpretability. However, many…

Machine Learning · Computer Science 2024-01-03 Matthias Jakobs , Amal Saadallah

Recent advancements in large language models have significantly improved their context windows, yet challenges in effective long-term memory management remain. We introduce MemTree, an algorithm that leverages a dynamic, tree-structured…

Computation and Language · Computer Science 2025-03-21 Alireza Rezazadeh , Zichao Li , Wei Wei , Yujia Bao

Memory systems are widely adopted to enhance LLMs for long-horizon tasks, and are commonly organized as multi-agent pipelines with memory building, summarizing, and retrieval agents. To empower this system, existing RL-based methods either…

Multiagent Systems · Computer Science 2026-05-07 Marina Mao , Alexandr Liu , Pengbo Li , Siheng Li , Bo Zhou , Xiang Wang
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