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Related papers: DiffDP: Radiotherapy Dose Prediction via a Diffusi…

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Deep learning (DL) has successfully automated dose distribution prediction in radiotherapy planning, enhancing both efficiency and quality. However, existing methods suffer from the over-smoothing problem for their commonly used L1 or L2…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Zhenghao Feng , Lu Wen , Jianghong Xiao , Yuanyuan Xu , Xi Wu , Jiliu Zhou , Xingchen Peng , Yan Wang

Treatment planning, which is a critical component of the radiotherapy workflow, is typically carried out by a medical physicist in a time-consuming trial-and-error manner. Previous studies have proposed knowledge-based or…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Yiwen Zhang , Chuanpu Li , Liming Zhong , Zeli Chen , Wei Yang , Xuetao Wang

Accurate dose distribution prediction is crucial in the radiotherapy planning. Although previous methods based on convolutional neural network have shown promising performance, they have the problem of over-smoothing, leading to prediction…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Xin Liao , Zhenghao Feng , Jianghong Xiao , Xingchen Peng , Yan Wang

Radiation therapy is crucial in cancer treatment. Experienced experts typically iteratively generate high-quality dose distribution maps, forming the basis for excellent radiation therapy plans. Therefore, automated prediction of dose…

Image and Video Processing · Electrical Eng. & Systems 2025-01-23 Linjie Fu , Xia Li , Xiuding Cai , Yingkai Wang , Xueyao Wang , Yali Shen , Yu Yao

Radiation therapy serves as an effective and standard method for cancer treatment. Excellent radiation therapy plans always rely on high-quality dose distribution maps obtained through repeated trial and error by experienced experts.…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Linjie Fu , Xia Li , Xiuding Cai , Yingkai Wang , Xueyao Wang , Yu Yao , Yali Shen

Radiotherapy treatment planning often relies on time-consuming, trial-and-error adjustments that heavily depend on the expertise of specialists, while existing deep learning methods face limitations in generalization, prediction accuracy,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Hui Xie , Haiqin Hu , Lijuan Ding , Qing Li , Yue Sun , Tao Tan

Purpose: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate,…

Medical Physics · Physics 2020-07-01 Yixun Xing , Dan Nguyen , Weiguo Lu , Ming Yang , Steve Jiang

Diffusion models generate data by learning to reverse a forward process, where samples are progressively perturbed with Gaussian noise according to a predefined noise schedule. From a geometric perspective, each noise schedule corresponds…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Teng Zhang , Hongxu Jiang , Kuang Gong , Wei Shao

We propose a simple, efficient, yet powerful framework for dense visual predictions based on the conditional diffusion pipeline. Our approach follows a "noise-to-map" generative paradigm for prediction by progressively removing noise from a…

Computer Vision and Pattern Recognition · Computer Science 2023-05-16 Yuanfeng Ji , Zhe Chen , Enze Xie , Lanqing Hong , Xihui Liu , Zhaoqiang Liu , Tong Lu , Zhenguo Li , Ping Luo

With the advancement of treatment modalities in radiation therapy for cancer patients, outcomes have improved, but at the cost of increased treatment plan complexity and planning time. The accurate prediction of dose distributions would…

Medical Physics · Physics 2018-12-03 Dan Nguyen , Troy Long , Xun Jia , Weiguo Lu , Xuejun Gu , Zohaib Iqbal , Steve Jiang

This work aims to study the generalizability of a pre-developed deep learning (DL) dose prediction model for volumetric modulated arc therapy (VMAT) for prostate cancer and to adapt the model to three different internal treatment planning…

In this study we performed a feasibility investigation on implementing a fast and accurate dose calculation based on a deep learning technique. A two dimensional (2D) fluence map was first converted into a three dimensional (3D) volume…

Medical Physics · Physics 2021-02-03 Jiawei Fan , Lei Xing , Peng Dong , Jiazhou Wang , Weigang Hu , Yong Yang

Diffusion probabilistic models have demonstrated an outstanding capability to model natural images and raw audio waveforms through a paired diffusion and reverse processes. The unique property of the reverse process (namely, eliminating…

Audio and Speech Processing · Electrical Eng. & Systems 2021-11-23 Yen-Ju Lu , Yu Tsao , Shinji Watanabe

Purpose: Radiation therapy treatment planning is a trial-and-error, often time-consuming process. An optimal dose distribution based on a specific anatomy can be predicted by pre-trained deep learning (DL) models. However, dose…

Medical Physics · Physics 2021-09-15 Jianhui Ma , Dan Nguyen , Ti Bai , Michael Folkerts , Xun Jia , Weiguo Lu , Linghong Zhou , Steve Jiang

Near infrared diffuse optical tomography (DOT) provides an imaging modality for the oxygenation of tissue. In this paper, we propose a novel machine learning algorithm based on time-domain radiative transfer equation. We use temporal…

Medical Physics · Physics 2020-11-26 Yu-ichi Takamizu , Masayuki Umemura , Hidenobu Yajima , Makito Abe , Yoko Hoshi

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Diffusion-based generative models (DBGMs) perturb data to a target noise distribution and reverse this process to generate samples. The choice of noising process, or inference diffusion process, affects both likelihoods and sample quality.…

Machine Learning · Computer Science 2023-03-06 Raghav Singhal , Mark Goldstein , Rajesh Ranganath

Predicting molecular conformations from molecular graphs is a fundamental problem in cheminformatics and drug discovery. Recently, significant progress has been achieved with machine learning approaches, especially with deep generative…

Machine Learning · Computer Science 2022-03-16 Minkai Xu , Lantao Yu , Yang Song , Chence Shi , Stefano Ermon , Jian Tang

Diffusion models have become fundamental tools for modeling data distributions in machine learning. Despite their success, these models face challenges when generating data with extreme brightness values, as evidenced by limitations…

Machine Learning · Statistics 2026-04-10 Takuro Kutsuna

Diffusion and flow matching models have achieved remarkable success in text-to-image generation. However, these models typically rely on the predetermined denoising schedules for all prompts. The multi-step reverse diffusion process can be…

Computer Vision and Pattern Recognition · Computer Science 2025-03-06 Zilyu Ye , Zhiyang Chen , Tiancheng Li , Zemin Huang , Weijian Luo , Guo-Jun Qi
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