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Machine learning (ML) holds great promise for clinical applications but is often hindered by limited access to high-quality data due to privacy concerns, high costs, and long timelines associated with clinical trials. While large language…

Computation and Language · Computer Science 2026-03-27 Zerui Xu , Fang Wu , Yingzhou Lu , Yuanyuan Zhang , Yue Zhao

Large Language Model (LLM) reasoning for complex tasks inherently involves a trade-off between solution accuracy and computational efficiency. The subsequent step of verification, while intended to improve performance, further complicates…

Artificial Intelligence · Computer Science 2025-05-20 Jianyuan Zhong , Zeju Li , Zhijian Xu , Xiangyu Wen , Kezhi Li , Qiang Xu

Quantifying uncertainty in automatically generated text is important for letting humans check potential hallucinations and making systems more reliable. Conformal prediction is an attractive framework to provide predictions imbued with…

Computation and Language · Computer Science 2024-02-02 Dennis Ulmer , Chrysoula Zerva , André F. T. Martins

We propose an end-to-end, domain-independent neural encoder-aligner-decoder model for selective generation, i.e., the joint task of content selection and surface realization. Our model first encodes a full set of over-determined database…

Computation and Language · Computer Science 2016-01-12 Hongyuan Mei , Mohit Bansal , Matthew R. Walter

Large Language Models (LLMs) have democratized synthetic data generation, which in turn has the potential to simplify and broaden a wide gamut of NLP tasks. Here, we tackle a pervasive problem in synthetic data generation: its generative…

Computation and Language · Computer Science 2023-05-25 Veniamin Veselovsky , Manoel Horta Ribeiro , Akhil Arora , Martin Josifoski , Ashton Anderson , Robert West

Use of computational methods to predict gene regulatory networks (GRNs) from gene expression data is a challenging task. Many studies have been conducted using unsupervised methods to fulfill the task; however, such methods usually yield…

Machine Learning · Computer Science 2016-08-15 Nihir Patel , Jason T. L. Wang

Current long-tailed semi-supervised learning methods assume that labeled data exhibit a long-tailed distribution, and unlabeled data adhere to a typical predefined distribution (i.e., long-tailed, uniform, or inverse long-tailed). However,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Yaxin Hou , Bo Han , Yuheng Jia , Hui Liu , Junhui Hou

Representations from large language models are highly effective at predicting BOLD fMRI responses to language stimuli. However, these representations are largely opaque: it is unclear what features of the language stimulus drive the…

Computation and Language · Computer Science 2025-03-04 Richard Antonello , Chandan Singh , Shailee Jain , Aliyah Hsu , Sihang Guo , Jianfeng Gao , Bin Yu , Alexander Huth

Auto-regressive sequence generative models trained by Maximum Likelihood Estimation suffer the exposure bias problem in practical finite sample scenarios. The crux is that the number of training samples for Maximum Likelihood Estimation is…

Machine Learning · Statistics 2020-07-14 Yuxuan Song , Ning Miao , Hao Zhou , Lantao Yu , Mingxuan Wang , Lei Li

Autoregressive language models are the currently dominant paradigm for text generation, but they have some fundamental limitations that cannot be remedied by scale-for example inherently sequential and unidirectional generation. While…

Computation and Language · Computer Science 2024-08-01 Yuchen Li , Alexandre Kirchmeyer , Aashay Mehta , Yilong Qin , Boris Dadachev , Kishore Papineni , Sanjiv Kumar , Andrej Risteski

Verifiable generation requires large language models (LLMs) to cite source documents supporting their outputs, thereby improve output transparency and trustworthiness. Yet, previous work mainly targets the generation of sentence-level…

Computation and Language · Computer Science 2024-06-11 Shuyang Cao , Lu Wang

A syntactic language model (SLM) incrementally generates a sentence with its syntactic tree in a left-to-right manner. We present Generative Pretrained Structured Transformers (GPST), an unsupervised SLM at scale capable of being…

Computation and Language · Computer Science 2024-06-18 Xiang Hu , Pengyu Ji , Qingyang Zhu , Wei Wu , Kewei Tu

Controlled generation refers to the problem of creating text that contains stylistic or semantic attributes of interest. Many approaches reduce this problem to training a predictor of the desired attribute. For example, researchers hoping…

Computation and Language · Computer Science 2023-06-02 Carolina Zheng , Claudia Shi , Keyon Vafa , Amir Feder , David M. Blei

Hallucination has been a popular topic in natural language generation (NLG). In real-world applications, unfaithful content can result in poor data quality or loss of trust from end users. Thus, it is crucial to fact-check before adopting…

Computation and Language · Computer Science 2025-02-11 Xiaonan Jing , Srinivas Billa , Danny Godbout

Generative cross-modal retrieval, which treats retrieval as a generation task, has emerged as a promising direction with the rise of Multimodal Large Language Models (MLLMs). In this setting, the model responds to a text query by generating…

Information Retrieval · Computer Science 2025-11-04 Tianyuan Li , Lei Wang , Ahtamjan Ahmat , Yating Yang , Bo Ma , Rui Dong , Bangju Han

Diffusion Large Language Models (DLLMs) are inherently ill-suited for variable-length generation, as their inference is defined on a fixed-length canvas and implicitly assumes a known target length. When the length is unknown, as in…

Computation and Language · Computer Science 2026-02-10 Zicong Cheng , Ruixuan Jia , Jia Li , Guo-Wei Yang , Meng-Hao Guo , Shi-Min Hu

With the recent proliferation of Large Language Models (LLMs), there has been an increasing demand for tools to detect machine-generated text. The effective detection of machine-generated text face two pertinent problems: First, they are…

Computation and Language · Computer Science 2024-04-04 Mazal Bethany , Brandon Wherry , Emet Bethany , Nishant Vishwamitra , Anthony Rios , Peyman Najafirad

Semi-supervised learning (SSL) has attracted enormous attention due to its vast potential of mitigating the dependence on large labeled datasets. The latest methods (e.g., FixMatch) use a combination of consistency regularization and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Yuhao Chen , Xin Tan , Borui Zhao , Zhaowei Chen , Renjie Song , Jiajun Liang , Xuequan Lu

Deploying generative machine learning techniques to generate novel chemical structures based on molecular fingerprint representation has been well established in molecular design. Typically, sequential learning (SL) schemes such as hidden…

Biomolecules · Quantitative Biology 2022-04-07 Mohammad Sajjad Ghaemi , Karl Grantham , Isaac Tamblyn , Yifeng Li , Hsu Kiang Ooi

Neural natural language generation (NLG) and understanding (NLU) models are data-hungry and require massive amounts of annotated data to be competitive. Recent frameworks address this bottleneck with generative models that synthesize weak…

Computation and Language · Computer Science 2021-02-09 Ernie Chang , Vera Demberg , Alex Marin
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