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Building on the conceptual framework presented in our previous work on agentic AI for pharmaceutical research, this paper provides a comprehensive technical analysis of Tippy's multi-agent system implementation for drug discovery laboratory…

With the popularity of cloud computing and machine learning, it has been a trend to outsource machine learning processes (including model training and model-based inference) to cloud. By the outsourcing, other than utilizing the extensive…

Cryptography and Security · Computer Science 2023-08-03 Pinglan Liu , Wensheng Zhang

This article proposes a design and implementation of a low cost two-tier architecture model for high availability cluster combined with load-balancing and shared storage technology to achieve desired scale of three-tier architecture for…

Networking and Internet Architecture · Computer Science 2014-06-24 A B M Moniruzzaman , Syed Akther Hossain

Frontier models increasingly adopt Mixture-of-Experts (MoE) architectures to achieve large-model performance at reduced cost. However, training MoE models on HPC platforms is hindered by large memory footprints, frequent large-scale…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-07 Sajal Dash , Feiyi Wang

Context: The combination of distributed stream processing with microservice architectures is an emerging pattern for building data-intensive software systems. In such systems, stream processing frameworks such as Apache Flink, Apache Kafka…

Software Engineering · Computer Science 2023-11-02 Sören Henning , Wilhelm Hasselbring

We describe Qonductor, a cloud orchestrator for hybrid quantum-classical applications that run on heterogeneous hybrid resources. Qonductor abstracts away the complexity of hybrid programming and resource management by exposing the…

In recent years, the issue of energy consumption in high performance computing (HPC) systems has attracted a great deal of attention. In response to this, many energy-aware algorithms have been developed in different layers of HPC systems,…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-05-13 Nikzad Babaii Rizvandi

Public infrastructure-as-a-service clouds, such as Amazon EC2, Google Compute Engine (GCE) and Microsoft Azure allow clients to run virtual machines (VMs) on shared physical infrastructure. This practice of multi-tenancy brings economies of…

Cryptography and Security · Computer Science 2015-07-14 Venkatanathan Varadarajan , Yinqian Zhang , Thomas Ristenpart , Michael Swift

In a new effort to make our research transparent and reproducible by others, we developed a workflow to run and share computational studies on the public cloud Microsoft Azure. It uses Docker containers to create an image of the application…

Computational Engineering, Finance, and Science · Computer Science 2020-07-24 Olivier Mesnard , Lorena A. Barba

The use of open-access software is an option that can be considered by those interested in power system studies. In addition, the combination of two or more of these tools can expand the capabilities and the fields of application of each…

Systems and Control · Electrical Eng. & Systems 2026-03-25 Juan A. Martinez-Velasco , Pau Casals-Torrens , Ricard Bosch-Tous , Alexandre Serrano-Fontova

Kubernetes is an open-source software for automating management of computerized services. Organizations, such as IBM, Capital One and Adidas use Kubernetes to deploy and manage their containers, and have reported benefits related to…

Cryptography and Security · Computer Science 2020-06-30 Md. Shazibul Islam Shamim , Farzana Ahamed Bhuiyan , Akond Rahman

Edge Computing emerges as a promising alternative of Cloud Computing, with scalable compute resources and services deployed in the path between IoT devices and Cloud. Since virtualization techniques can be applied on Edge compute nodes,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-13 Joanna Georgiou , Moysis Symeonides , George Pallis , Marios D. Dikaiakos

With the rise of machine learning, inference on deep neural networks (DNNs) has become a core building block on the critical path for many cloud applications. Applications today rely on isolated ad-hoc deployments that force users to…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-24 Amit Samanta , Suhas Shrinivasan , Antoine Kaufmann , Jonathan Mace

Problem Definition: Allocating sufficient capacity to cloud services is a challenging task, especially when demand is time-varying, heterogeneous, contains batches, and requires multiple types of resources for processing. In this setting,…

Applications · Statistics 2022-09-21 Eugene Furman , Arik Senderovich , Shane Bergsma , J. Christopher Beck

A major concern in cloud/edge storage systems is serving a large number of users simultaneously. The service rate region is introduced recently as an important performance metric for coded distributed systems, which is defined as the set of…

Information Theory · Computer Science 2020-10-27 Fatemeh Kazemi , Sascha Kurz , Emina Soljanin , Alex Sprintson

The rapid development of cloud-native architecture has promoted the widespread application of container technology, but the optimization problems in container scheduling and resource management still face many challenges. This paper…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-12-24 Xiaoye Wang

With the rapid rise of intelligent data services, modern enterprises increasingly require efficient, multimodal, and cost-effective data analytics infrastructures. However, in ByteDance's production environments, existing systems fall short…

With the success of deep learning techniques in a broad range of application domains, many deep learning software frameworks have been developed and are being updated frequently to adapt to new hardware features and software libraries,…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-11-10 Pengfei Xu , Shaohuai Shi , Xiaowen Chu

Cloud computing has made federated database systems (FDBS) significantly more practical to implement than in the past. As part of a recent Web-based Geographic Information System (WebGIS) project, we are employing cloud-native technologies…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-11-02 Zheng Li , Nicolás Saldías-Vallejos , María Andrea Rodríguez , Austen Rainer

Cloud-based storage platforms are becoming more common in both academic and business settings due to their flexible access to data and support for collaborative functionalities. As reliability becomes a vital requirement, particularly for…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-06 Alison Silva , Gustavo Callou