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The dynamics of short-lived mRNA results in bursts of protein production in gene regulatory networks. We investigate the propagation of bursting noise between different levels of mathematical modelling, and demonstrate that conventional…

Molecular Networks · Quantitative Biology 2016-01-14 Yen Ting Lin , Tobias Galla

The mammalian cortex is divided into architectonic and functionally distinct areas. There is growing experimental evidence that their emergence and development is controlled by both epigenetic and genetic factors. The latter were recently…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jan Karbowski , G. B. Ermentrout

We present Brownian dynamics simulations of the facilitated diffusion of a protein, modelled as a sphere with a binding site on its surface, along DNA, modelled as a semi-flexible polymer. We consider both the effect of DNA organisation in…

Biological Physics · Physics 2012-12-10 C. A. Brackley , M. E. Cates , D. Marenduzzo

Diffusion-driven patterns appear on curved surfaces in many settings, initiated by unstable modes of an underlying Laplacian operator. On a flat surface or perfect sphere, the patterns are degenerate, reflecting translational/rotational…

Soft Condensed Matter · Physics 2025-09-09 John R. Frank , Jemal Guven , Mehran Kardar , Leyna Shackleton

The spatial organization of individuals and their interactions in communities are important factors known to preserve diversity in many complex systems. Inspired by metapopulation models from ecology, we study opinion formation using a…

Physics and Society · Physics 2026-05-19 Tim Mauch , Thilo Gross

Understanding the structure of real data is paramount in advancing modern deep-learning methodologies. Natural data such as images are believed to be composed of features organized in a hierarchical and combinatorial manner, which neural…

Machine Learning · Statistics 2024-12-25 Antonio Sclocchi , Alessandro Favero , Matthieu Wyart

The current paper proposes a novel predictive coding type neural network model, the predictive multiple spatio-temporal scales recurrent neural network (P-MSTRNN). The P-MSTRNN learns to predict visually perceived human whole-body cyclic…

Computer Vision and Pattern Recognition · Computer Science 2017-09-07 Minkyu Choi , Jun Tani

This paper studies spatial patterns formed by proximate population migration driven by real wage gradients and other idiosyncratic factors. The model consists of a tractable core-periphery model incorporating a quasi-linear log utility…

Theoretical Economics · Economics 2025-07-23 Kensuke Ohtake

A fundamental task in developmental biology is to identify the mechanisms which drive morphogenesis. In many cases, pattern formation is driven by the positional information determined by both the gradient of maternal factors and hard-wired…

Molecular Networks · Quantitative Biology 2007-05-23 L. Diambra , Luciano da Fontoura Costa

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

We present a mathematical study for the development of Multiple Sclerosis in which a spatio-temporal kinetic { theory} model describes, at the mesoscopic level, the dynamics of a high number of interacting agents. We consider both…

Analysis of PDEs · Mathematics 2026-01-07 Romina Travaglini , João Miguel Oliveira

This paper addresses the question of how population diffusion affects the formation of the spatial patterns in the spatial epidemic model by Turing mechanisms. In particular, we present theoretical analysis to results of the numerical…

Populations and Evolution · Quantitative Biology 2009-09-29 Quan-Xing Liu , Zhen Jin

Statistical and mathematical modeling are crucial to describe, interpret, compare and predict the behavior of complex biological systems including the organization of hematopoietic stem and progenitor cells in the bone marrow environment.…

Quantitative Methods · Quantitative Biology 2018-09-07 Walter de Back , Thomas Zerjatke , Ingo Roeder

A hallmark of a plethora of intracellular signaling pathways is the spatial separation of activation and deactivation processes that potentially results in precipitous gradients of activated proteins. The classical Metabolic Control…

Analysis of PDEs · Mathematics 2007-05-23 Mark A. Peletier , Hans V. Westerhoff , Boris N. Kholodenko

Spatial organization of proteins in cells is important for many biological functions. In general, the nonlinear, spatially coupled models for protein-pattern formation are only accessible to numerical simulations, which has limited insight…

Pattern Formation and Solitons · Physics 2021-04-16 Fridtjof Brauns , Jacob Halatek , Erwin Frey

Most existing cross-modal generative methods based on diffusion models use guidance to provide control over the latent space to enable conditional generation across different modalities. Such methods focus on providing guidance through…

Machine Learning · Computer Science 2023-05-31 Zizhao Hu , Mohammad Rostami

Nonlinear reaction-diffusion systems admit a wide variety of spatiotemporal patterns or structures. In this lecture, we point out that there is certain advantage in studying discrete arrays, namely cellular neural/nonlinear networks (CNNs),…

Pattern Formation and Solitons · Physics 2007-05-23 M. Lakshmanan , P. Muruganandam

Recent advances in diffusion models have significantly improved the synthesis of materials, textures, and 3D shapes. By conditioning these models via text or images, users can guide the generation, reducing the time required to create…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Marzia Riso , Giuseppe Vecchio , Fabio Pellacini

Cyanobacteria forming one-dimensional filaments are paradigmatic model organisms of the transition between unicellular and multicellular living forms. Under nitrogen limiting conditions, in filaments of the genus Anabaena, some cells…

Cell Behavior · Quantitative Biology 2016-10-10 Javier Munoz-Garcia , Saul Ares

In this paper, we investigate the emergence of a predator-prey model with Beddington-DeAngelis-type functional response and reaction-diffusion. We derive the conditions for Hopf and Turing bifurcation on the spatial domain. Based on the…

Populations and Evolution · Quantitative Biology 2008-01-08 Weiming Wang , Lei Zhang , Yakui Xue , Zhen Jin