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Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi

The high incidence and mortality rates associated with respiratory diseases underscores the importance of early screening. Machine learning models can automate clinical consultations and auscultation, offering vital support in this area.…

Machine Learning · Computer Science 2024-10-10 Yuwei Zhang , Tong Xia , Aaqib Saeed , Cecilia Mascolo

Electronic Health Records (EHRs) offer considerable potential for clinical prediction, but their complexity and heterogeneity challenge traditional machine learning. Domain-specific EHR foundation models trained on unlabeled EHR data have…

Large language models (LLMs) are capable of many natural language tasks, yet they are far from perfect. In health applications, grounding and interpreting domain-specific and non-linguistic data is crucial. This paper investigates the…

Computation and Language · Computer Science 2024-04-30 Yubin Kim , Xuhai Xu , Daniel McDuff , Cynthia Breazeal , Hae Won Park

Recent advancements in artificial intelligence (AI), especially large language models (LLMs), have significantly advanced healthcare applications and demonstrated potentials in intelligent medical treatment. However, there are conspicuous…

Computation and Language · Computer Science 2025-05-26 Qinkai Yu , Mingyu Jin , Dong Shu , Chong Zhang , Lizhou Fan , Wenyue Hua , Suiyuan Zhu , Yanda Meng , Zhenting Wang , Mengnan Du , Yongfeng Zhang

Health monitoring systems have revolutionized modern healthcare by enabling the continuous capture of physiological and behavioral data, essential for preventive measures and early health intervention. While integrating this data with Large…

Machine Learning · Computer Science 2024-06-26 Ajan Subramanian , Zhongqi Yang , Iman Azimi , Amir M. Rahmani

Large language models (LLMs) can capture rich representations of concepts that are useful for real-world tasks. However, language alone is limited. While existing LLMs excel at text-based inferences, health applications require that models…

Computation and Language · Computer Science 2023-05-26 Xin Liu , Daniel McDuff , Geza Kovacs , Isaac Galatzer-Levy , Jacob Sunshine , Jiening Zhan , Ming-Zher Poh , Shun Liao , Paolo Di Achille , Shwetak Patel

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

Network device and system health management is the foundation of modern network operations and maintenance. Traditional health management methods, relying on expert identification or simple rule-based algorithms, struggle to cope with the…

Networking and Internet Architecture · Computer Science 2026-03-24 Fengxiao Tang , Xiaonan Wang , Xun Yuan , Linfeng Luo , Ming Zhao , Tianchi Huang , Nei Kato

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

The intricate relationship between genetic variation and human diseases has been a focal point of medical research, evidenced by the identification of risk genes regarding specific diseases. The advent of advanced genome sequencing…

Quantitative Methods · Quantitative Biology 2024-01-19 Jiayu Chang , Shiyu Wang , Chen Ling , Zhaohui Qin , Liang Zhao

Large language models (LLMs) hold promise for transforming healthcare, from streamlining administrative and clinical workflows to enriching patient engagement and advancing clinical decision-making. However, their successful integration…

Computers and Society · Computer Science 2025-04-04 Mohammed Al-Garadi , Tushar Mungle , Abdulaziz Ahmed , Abeed Sarker , Zhuqi Miao , Michael E. Matheny

Large Language Model (LLM)-based systems present new opportunities for autonomous health monitoring in sensor-rich industrial environments. This study explores the potential of LLMs to detect and classify faults directly from sensor data,…

Artificial Intelligence · Computer Science 2025-09-30 Xian Yeow Lee , Lasitha Vidyaratne , Ahmed Farahat , Chetan Gupta

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

Digital Libraries · Computer Science 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Multimodal Large Language Models (MLLMs) have shown transformative potential in medical applications, yet their performance is hindered by conventional data curation strategies that rely on coarse-grained partitioning by modality or…

Computation and Language · Computer Science 2026-04-29 Jianghang Lin , Haihua Yang , Deli Yu , Kai Wu , Kai Ye , Jinghao Lin , Zihan Wang , Yuhang Wu , Liujuan Cao

The application of large language models (LLMs) in healthcare has gained significant attention due to their ability to process complex medical data and provide insights for clinical decision-making. These models have demonstrated…

Computer Vision and Pattern Recognition · Computer Science 2024-09-26 Amna Khalid , Ayma Khalid , Umar Khalid

Large Language Models (LLMs) have fundamentally transformed approaches to Natural Language Processing (NLP) tasks across diverse domains. In healthcare, accurate and cost-efficient text classification is crucial, whether for clinical notes…

Computation and Language · Computer Science 2026-02-16 Hajar Sakai , Sarah S. Lam

Large Language Models (LLMs) are increasingly being integrated into various medical fields, including mental health support systems. However, there is a gap in research regarding the effectiveness of LLMs in non-English mental health…

Computation and Language · Computer Science 2026-02-10 Konstantinos Skianis , John Pavlopoulos , A. Seza Doğruöz
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