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While hyperspectral images (HSI) benefit from numerous spectral channels that provide rich information for classification, the increased dimensionality and sensor variability make them more sensitive to distributional discrepancies across…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Taiqin Chen , Yifeng Wang , Xiaochen Feng , Zhilin Zhu , Hao Sha , Yingjian Li , Yongbing Zhang

Convolutional neural networks have been widely applied to medical image segmentation and have achieved considerable performance. However, the performance may be significantly affected by the domain gap between training data (source domain)…

Image and Video Processing · Electrical Eng. & Systems 2022-07-28 Junyan Lyu , Yiqi Zhang , Yijin Huang , Li Lin , Pujin Cheng , Xiaoying Tang

Training robust learning algorithms across different medical imaging modalities is challenging due to the large domain gap. Unsupervised domain adaptation (UDA) mitigates this problem by using annotated images from the source domain and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Chen Li , Meilong Xu , Xiaoling Hu , Weimin Lyu , Chao Chen

Classifier-free guidance (CFG) has become an essential component of modern conditional diffusion models. Although highly effective in practice, the underlying mechanisms by which CFG enhances quality, detail, and prompt alignment are not…

Machine Learning · Computer Science 2025-06-25 Seyedmorteza Sadat , Tobias Vontobel , Farnood Salehi , Romann M. Weber

Data diversity and volume are crucial to the success of training deep learning models, while in the medical imaging field, the difficulty and cost of data collection and annotation are especially huge. Specifically in robotic surgery, data…

Computer Vision and Pattern Recognition · Computer Science 2022-07-08 An Wang , Mobarakol Islam , Mengya Xu , Hongliang Ren

Large-scale, big-variant, high-quality data are crucial for developing robust and successful deep-learning models for medical applications since they potentially enable better generalization performance and avoid overfitting. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Zheyuan Zhang , Lanhong Yao , Bin Wang , Debesh Jha , Gorkem Durak , Elif Keles , Alpay Medetalibeyoglu , Ulas Bagci

In medical image segmentation, supervised deep networks' success comes at the cost of requiring abundant labeled data. While asking domain experts to annotate only one or a few of the cohort's images is feasible, annotating all available…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Devavrat Tomar , Behzad Bozorgtabar , Manana Lortkipanidze , Guillaume Vray , Mohammad Saeed Rad , Jean-Philippe Thiran

Much of federated learning (FL) focuses on settings where local dataset statistics remain the same between training and testing. However, this assumption often does not hold in practice due to distribution shifts, motivating the development…

Machine Learning · Computer Science 2026-02-02 Shahryar Zehtabi , Dong-Jun Han , Seyyedali Hosseinalipour , Christopher G. Brinton

Although SAM-based single-source domain generalization models for medical image segmentation can mitigate the impact of domain shift on the model in cross-domain scenarios, these models still face two major challenges. First, the…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Huanli Zhuo , Leilei Ma , Haifeng Zhao , Shiwei Zhou , Dengdi Sun , Yanping Fu

Multimodal models ideally should generalize to unseen domains while remaining data-efficient to reduce annotation costs. To this end, we introduce and study a new problem, Semi-Supervised Multimodal Domain Generalization (SSMDG), which aims…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Hongzhao Li , Hao Dong , Hualei Wan , Shupan Li , Mingliang Xu , Muhammad Haris Khan

Domain Generalization (DG) aims to resolve distribution shifts between source and target domains, and current DG methods are default to the setting that data from source and target domains share identical categories. Nevertheless, there…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Zining Chen , Weiqiu Wang , Zhicheng Zhao , Fei Su , Aidong Men , Hongying Meng

Based on the Denoising Diffusion Probabilistic Model (DDPM), medical image segmentation can be described as a conditional image generation task, which allows to compute pixel-wise uncertainty maps of the segmentation and allows an implicit…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Xutao Guo , Yanwu Yang , Chenfei Ye , Shang Lu , Yang Xiang , Ting Ma

Manual annotation of 3D medical images for segmentation tasks is tedious and time-consuming. Moreover, data privacy limits the applicability of crowd sourcing to perform data annotation in medical domains. As a result, training deep neural…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Ruitong Sun , Mohammad Rostami

Source-Free Domain Adaptation (SFDA) is emerging as a compelling solution for medical image segmentation under privacy constraints, yet current approaches often ignore sample difficulty and struggle with noisy supervision under domain…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Quang-Khai Bui-Tran , Thanh-Huy Nguyen , Hoang-Thien Nguyen , Ba-Thinh Lam , Nguyen Lan Vi Vu , Phat K. Huynh , Ulas Bagci , Min Xu

Generalizing from a single labeled source domain to unseen target domains, without access to any target data during training, remains a fundamental challenge in robust machine learning. We address this underexplored setting, known as Single…

Machine Learning · Computer Science 2026-04-09 Marzi Heidari , Hanping Zhang , Hao Yan , Yuhong Guo

Domain-invariant representation learning is a powerful method for domain generalization. Previous approaches face challenges such as high computational demands, training instability, and limited effectiveness with high-dimensional data,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Yuheng Xu , Taiping Zhang

Automated medical image segmentation using deep neural networks typically requires substantial supervised training. However, these models fail to generalize well across different imaging modalities. This shortcoming, amplified by the…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Malo Alefsen de Boisredon d'Assier , Eugene Vorontsov , Samuel Kadoury

In this work, we investigate the unexplored intersection of domain generalization (DG) and data-free learning. In particular, we address the question: How can knowledge contained in models trained on different source domains be merged into…

Machine Learning · Computer Science 2022-11-15 Ahmed Frikha , Haokun Chen , Denis Krompaß , Thomas Runkler , Volker Tresp

Single domain generalization (SDG) aims to train a robust model against unknown target domain shifts using data from a single source domain. Data augmentation has been proven an effective approach to SDG. However, the utility of standard…

Computer Vision and Pattern Recognition · Computer Science 2024-02-15 Guangtao Zheng , Mengdi Huai , Aidong Zhang

Domain generalization (DG) aims to learn models that perform well on unseen target domains by training on multiple source domains. Sharpness-Aware Minimization (SAM), known for finding flat minima that improve generalization, has therefore…

Machine Learning · Statistics 2025-07-01 Youngjun Song , Youngsik Hwang , Jonghun Lee , Heechang Lee , Dong-Young Lim