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The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…

Depression is one of the most prevalent mental disorders, which seriously affects one's life. Traditional depression diagnostics commonly depends on rating with scales, which can be labor-intensive and subjective. In this context, Automatic…

Machine Learning · Computer Science 2022-03-02 Yanrong Guo , Chenyang Zhu , Shijie Hao , Richang Hong

Graph neural networks (GNNs) are powerful machine learning models designed to handle irregularly structured data. However, their generic design often proves inadequate for analyzing brain connectomes in Alzheimer's Disease (AD),…

Machine Learning · Computer Science 2024-12-10 Zhepeng Wang , Runxue Bao , Yawen Wu , Guodong Liu , Lei Yang , Liang Zhan , Feng Zheng , Weiwen Jiang , Yanfu Zhang

Accurate yet interpretable image-based diagnosis remains a central challenge in medical AI, particularly in settings characterized by limited data, subtle visual cues, and high-stakes clinical decision-making. Most existing vision models…

Artificial Intelligence · Computer Science 2025-12-23 Midhat Urooj , Ayan Banerjee , Sandeep Gupta

Anomaly detection is an important task for complex systems (e.g., industrial facilities, manufacturing, large-scale science experiments), where failures in a sub-system can lead to low yield, faulty products, or even damage to components.…

Machine Learning · Computer Science 2023-09-06 Ryan Humble , Zhe Zhang , Finn O'Shea , Eric Darve , Daniel Ratner

Diagnosing a whole-slide image is an interactive, multi-stage process of changing magnification and moving between fields. Although recent pathology foundation models demonstrated superior performances, practical agentic systems that decide…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Sheng Wang , Ruiming Wu , Charles Herndon , Yihang Liu , Shunsuke Koga , Jeanne Shen , Zhi Huang

Automatic Differentiation (AD) is instrumental for science and industry. It is a tool to evaluate the derivative of a function specified through a computer program. The range of AD application domain spans from Machine Learning to Robotics…

Mathematical Software · Computer Science 2023-03-01 Ioana Ifrim , Vassil Vassilev , David J Lange

International Classification of Diseases (ICD) are the de facto codes used globally for clinical coding. These codes enable healthcare providers to claim reimbursement and facilitate efficient storage and retrieval of diagnostic…

Computation and Language · Computer Science 2022-02-22 Pavithra Rajendran , Alexandros Zenonos , Josh Spear , Rebecca Pope

Currently, every 1 in 54 children have been diagnosed with Autism Spectrum Disorder (ASD), which is 178% higher than it was in 2000. An early diagnosis and treatment can significantly increase the chances of going off the spectrum and…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Spencer He , Ryan Liu

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

Designing sustainable medical devices requires balancing environmental, economic, and social demands, yet trade-offs across these pillars are difficult to identify using manual assessment alone. Current methods depend heavily on expert…

Physics and Society · Physics 2025-12-16 Apala Chakrabarti

Alzheimer's Disease (AD) is marked by significant inter-individual variability in its progression, complicating accurate prognosis and personalized care planning. This heterogeneity underscores the critical need for predictive models…

Machine Learning · Computer Science 2025-05-01 Gulsah Hancerliogullari Koksalmis , Bulent Soykan , Laura J. Brattain , Hsin-Hsiung Huang

Research in machine learning for autism spectrum disorder (ASD) classification bears the promise to improve clinical diagnoses. However, recent studies in clinical imaging have shown the limited generalization of biomarkers across and…

Machine Learning · Computer Science 2022-09-23 Christian Gerloff , Kerstin Konrad , Jana Kruppa , Martin Schulte-Rüther , Vanessa Reindl

Accurate and robust prediction of patient's response to drug treatments is critical for developing precision medicine. However, it is often difficult to obtain a sufficient amount of coherent drug response data from patients directly for…

Machine Learning · Computer Science 2021-02-02 Di He , Lei Xie

Anomaly detection (AD) plays a vital role across a wide range of real-world domains by identifying data instances that deviate from expected patterns, potentially signaling critical events such as system failures, fraudulent activities, or…

Machine Learning · Computer Science 2025-07-11 Amirhossein Sadough , Mahyar Shahsavari , Mark Wijtvliet , Marcel van Gerven

Traditional network diagnosis methods of Client-Terminal Device (CTD) problems tend to be laborintensive, time consuming, and contribute to increased customer dissatisfaction. In this paper, we propose an automated solution for rapidly…

Networking and Internet Architecture · Computer Science 2012-07-18 Chathuranga Widanapathirana , Y. Ahmet Şekercioǧlu , Milosh V. Ivanovich , Paul G. Fitzpatrick , Jonathan C. Li

Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

Medical automatic diagnosis aims to imitate human doctors in real-world diagnostic processes and to achieve accurate diagnoses by interacting with the patients. The task is formulated as a sequential decision-making problem with a series of…

Machine Learning · Computer Science 2022-06-07 Hongyi Yuan , Sheng Yu

The current clinical diagnosis framework of Alzheimer's disease (AD) involves multiple modalities acquired from multiple diagnosis stages, each with distinct usage and cost. Previous AD diagnosis research has predominantly focused on how to…

Computer Vision and Pattern Recognition · Computer Science 2024-07-29 Yuxiao Liu , Mianxin Liu , Yuanwang Zhang , Kaicong Sun , Dinggang Shen

This paper presents a novel anomaly detection methodology termed Statistical Aggregated Anomaly Detection (SAAD). The SAAD approach integrates advanced statistical techniques with machine learning, and its efficacy is demonstrated through…

Machine Learning · Computer Science 2024-06-14 Dacian Goina , Eduard Hogea , George Maties