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Live cell microscopy sequences exhibit complex spatial structures and complicated temporal behaviour, making their analysis a challenging task. Considering cell segmentation problem, which plays a significant role in the analysis, the…

Computer Vision and Pattern Recognition · Computer Science 2019-01-08 Assaf Arbelle , Tammy Riklin Raviv

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu

Nucleus image segmentation is a crucial step in the analysis, pathological diagnosis, and classification, which heavily relies on the quality of nucleus segmentation. However, the complexity of issues such as variations in nucleus size,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-11 Junzhou Chen , Qian Huang , Yulin Chen , Linyi Qian , Chengyuan Yu

Accurate segmentation of anatomical structures and abnormalities in medical images is crucial for computer-aided diagnosis and analysis. While deep learning techniques excel at this task, their computational demands pose challenges.…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Syed Javed , Tariq M. Khan , Abdul Qayyum , Hamid Alinejad-Rokny , Arcot Sowmya , Imran Razzak

Recently, deep learning with Convolutional Neural Networks (CNNs) and Transformers has shown encouraging results in fully supervised medical image segmentation. However, it is still challenging for them to achieve good performance with…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Xiangde Luo , Minhao Hu , Tao Song , Guotai Wang , Shaoting Zhang

Segmenting 3D cell nuclei from microscopy image volumes is critical for biological and clinical analysis, enabling the study of cellular expression patterns and cell lineages. However, current datasets for neuronal nuclei usually contain…

Fully Convolutional Neural Networks (FCNNs) with contracting and expanding paths have shown prominence for the majority of medical image segmentation applications since the past decade. In FCNNs, the encoder plays an integral role by…

Image and Video Processing · Electrical Eng. & Systems 2021-10-12 Ali Hatamizadeh , Yucheng Tang , Vishwesh Nath , Dong Yang , Andriy Myronenko , Bennett Landman , Holger Roth , Daguang Xu

The high cure rate of cancer is inextricably linked to physicians' accuracy in diagnosis and treatment, therefore a model that can accomplish high-precision tumor segmentation has become a necessity in many applications of the medical…

Image and Video Processing · Electrical Eng. & Systems 2023-07-26 Zeqiu. Yu , Shuo. Han , Ziheng. Song

Though performed almost effortlessly by humans, segmenting 2D gray-scale or color images into respective regions of interest (e.g.~background, objects, or portions of objects) constitutes one of the greatest challenges in science and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Alexandre Benatti , Luciano da F. Costa

Deep learning has revolutionized medical and biological imaging, particularly in segmentation tasks. However, segmenting biological cells remains challenging due to the high variability and complexity of cell shapes. Addressing this…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Tianhao Zhang , Heather J. McCourty , Berardo M. Sanchez-Tafolla , Anton Nikolaev , Lyudmila S. Mihaylova

Nuclei segmentation is a fundamental but challenging task in the quantitative analysis of histopathology images. Although fully-supervised deep learning-based methods have made significant progress, a large number of labeled images are…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Xinyi Yu , Guanbin Li , Wei Lou , Siqi Liu , Xiang Wan , Yan Chen , Haofeng Li

In this paper, we propose TransMEF, a transformer-based multi-exposure image fusion framework that uses self-supervised multi-task learning. The framework is based on an encoder-decoder network, which can be trained on large natural image…

Computer Vision and Pattern Recognition · Computer Science 2021-12-16 Linhao Qu , Shaolei Liu , Manning Wang , Zhijian Song

Over the past two decades, machine analysis of medical imaging has advanced rapidly, opening up significant potential for several important medical applications. As complicated diseases increase and the number of cases rises, the role of…

Image and Video Processing · Electrical Eng. & Systems 2024-05-08 Fares Bougourzi , Fadi Dornaika , Cosimo Distante , Abdelmalik Taleb-Ahmed

Though U-Net has achieved tremendous success in medical image segmentation tasks, it lacks the ability to explicitly model long-range dependencies. Therefore, Vision Transformers have emerged as alternative segmentation structures recently,…

Image and Video Processing · Electrical Eng. & Systems 2021-11-12 Hongyi Wang , Shiao Xie , Lanfen Lin , Yutaro Iwamoto , Xian-Hua Han , Yen-Wei Chen , Ruofeng Tong

Accurate and efficient cell nuclei detection and classification in histopathological Whole Slide Images (WSIs) are pivotal for digital pathology applications. Traditional cell segmentation approaches, while commonly used, are…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Oscar Pina , Eduard Dorca , Verónica Vilaplana

High-resolution images are preferable in medical imaging domain as they significantly improve the diagnostic capability of the underlying method. In particular, high resolution helps substantially in improving automatic image segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-03 Muhammad Hamza Sharif , Dmitry Demidov , Asif Hanif , Mohammad Yaqub , Min Xu

Current medical image segmentation approaches have limitations in deeply exploring multi-scale information and effectively combining local detail textures with global contextual semantic information. This results in over-segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Zhenkun Lu , Chaoyin She , Wei Wang , Qinghua Huang

Brain tumor segmentation is an active research area due to the difficulty in delineating highly complex shaped and textured tumors as well as the failure of the commonly used U-Net architectures. The combination of different neural…

Image and Video Processing · Electrical Eng. & Systems 2023-08-02 Lanhong Yao , Zheyuan Zhang , Ulas Bagci

Accurate image segmentation plays a crucial role in medical image analysis, yet it faces great challenges of various shapes, diverse sizes, and blurry boundaries. To address these difficulties, square kernel-based encoder-decoder…

Image and Video Processing · Electrical Eng. & Systems 2022-01-02 Qian Yu , Lei Qi , Luping Zhou , Lei Wang , Yilong Yin , Yinghuan Shi , Wuzhang Wang , Yang Gao

There is large consent that successful training of deep networks requires many thousand annotated training samples. In this paper, we present a network and training strategy that relies on the strong use of data augmentation to use the…

Computer Vision and Pattern Recognition · Computer Science 2015-05-19 Olaf Ronneberger , Philipp Fischer , Thomas Brox