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Pathology images are crucial for diagnosing and managing various diseases by visualizing cellular and tissue-level abnormalities. Recent advancements in artificial intelligence (AI), particularly multimodal models like ChatGPT, have shown…

Human-Computer Interaction · Computer Science 2024-09-25 Mianxin Liu , Jianfeng Wu , Fang Yan , Hongjun Li , Wei Wang , Shaoting Zhang , Zhe Wang

With the development of digital imaging in medical microscopy, artificial intelligent-based analysis of pathological whole slide images (WSIs) provides a powerful tool for cancer diagnosis. Limited by the expensive cost of pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Jiawen Li , Qiehe Sun , Renao Yan , Yizhi Wang , Yuqiu Fu , Yani Wei , Tian Guan , Huijuan Shi , Yonghonghe He , Anjia Han

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

Manually annotated data is key to developing text-mining and information-extraction algorithms. However, human annotation requires considerable time, effort and expertise. Given the rapid growth of biomedical literature, it is paramount to…

Human-Computer Interaction · Computer Science 2020-04-27 Rezarta Islamaj , Dongseop Kwon , Sun Kim , Zhiyong Lu

Computational pathology has advanced rapidly in recent years, driven by domain-specific image encoders and growing interest in using vision-language models to answer natural-language questions about diseases. Yet, the core problem behind…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Wentao Huang , Weimin Lyu , Peiliang Lou , Qingqiao Hu , Xiaoling Hu , Shahira Abousamra , Wenchao Han , Ruifeng Guo , Jiawei Zhou , Chao Chen , Chen Wang

Digital pathology has fundamentally altered diagnostic workflows by enabling the computational analysis of gigapixel Whole Slide Images (WSIs), yet effectively deciphering their complex tumor microenvironments remains a formidable…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Xuemei Qiu , Dawei Fan , Yebin Huang , Yanping Chen , Lifang Wei

Deep-learning-based pipelines have shown the potential to revolutionalize microscopy image diagnostics by providing visual augmentations to a trained pathology expert. However, to match human performance, the methods rely on the…

Automated object detection has become increasingly valuable across diverse applications, yet efficient, high-quality annotation remains a persistent challenge. In this paper, we present the development and evaluation of a platform designed…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Sönke Tenckhoff , Mario Koddenbrock , Erik Rodner

Histopathology remains the gold standard for diagnosis of various cancers. Recent advances in computer vision, specifically deep learning, have facilitated the analysis of histopathology images for various tasks, including immune cell…

Quantitative Methods · Quantitative Biology 2023-11-02 Jakub R. Kaczmarzyk , Tahsin M. Kurc , Shahira Abousamra , Rajarsi Gupta , Joel H. Saltz , Peter K. Koo

Deep learning has shown strong potential in cancer classification from whole-slide images (WSIs), but the need for extensive expert annotations often limits its success. Annotation-free approaches, such as multiple instance learning (MIL)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Willmer Rafell Quinones Robles , Sakonporn Noree , Jongwoo Kim , Young Sin Ko , Bryan Wong , Mun Yong Yi

Developing an AI-assisted gland segmentation method from histology images is critical for automatic cancer diagnosis and prognosis; however, the high cost of pixel-level annotations hinders its applications to broader diseases. Existing…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Yi Li , Yiduo Yu , Yiwen Zou , Tianqi Xiang , Xiaomeng Li

Pathology, the microscopic examination of diseased tissue, is critical for diagnosing various medical conditions, particularly cancers. Traditional methods are labor-intensive and prone to human error. Digital pathology, which converts…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova

Whole Slide Images (WSIs) in digital pathology are used to diagnose cancer subtypes. The difference in procedures to acquire WSIs at various trial sites gives rise to variability in the histopathology images, thus making consistent…

Image and Video Processing · Electrical Eng. & Systems 2022-04-07 Milad Sikaroudi , Shahryar Rahnamayan , H. R. Tizhoosh

Artificial intelligence-enabled histopathological data analysis has become a valuable assistant to the pathologist. However, existing models lack representation and inference abilities compared with those of pathologists, especially in…

Computer Vision and Pattern Recognition · Computer Science 2023-04-20 Bo Yu , Hechang Chen , Yunke Zhang , Lele Cong , Shuchao Pang , Hongren Zhou , Ziye Wang , Xianling Cong

Imaging has occupied a huge role in the management of patients, whether hospitalized or not. Depending on the patients clinical problem, a variety of imaging modalities were available for use. This gave birth of the annotation of medical…

Computer Vision and Pattern Recognition · Computer Science 2013-07-04 Mouhamed Gaith Ayadi , Riadh Bouslimi , Jalel Akaichi

Manual annotation of medical images is a labor-intensive and time-consuming process, posing a significant bottleneck in the development and deployment of robust medical imaging AI systems. This paper introduces a novel hands-free Human-AI…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yizhe Zhang

The classification of histopathology images fundamentally differs from traditional image classification tasks because histopathology images naturally exhibit a range of diagnostic features, resulting in a diverse range of annotator…

Image and Video Processing · Electrical Eng. & Systems 2022-01-31 Jerry Wei , Lorenzo Torresani , Jason Wei , Saeed Hassanpour

Deep neural networks (DNNs) have exhibited remarkable success in the field of histopathology image analysis. On the other hand, the contemporary trend of employing large models and extensive datasets has underscored the significance of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Cong Cong , Shiyu Xuan , Sidong Liu , Maurice Pagnucco , Shiliang Zhang , Yang Song

The lack of annotated datasets is a major bottleneck for training new task-specific supervised machine learning models, considering that manual annotation is extremely expensive and time-consuming. To address this problem, we present MONAI…

Information system designers face many challenges w.r.t. selecting appropriate semantic technologies and deciding on a modelling approach for their system. However, there is no clear methodology yet to evaluate "semantically enriched"…

Multimedia · Computer Science 2010-12-10 Jasmin Opitz , Bijan Parsia , Ulrike Sattler
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