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In the healthcare industry, researchers have been developing machine learning models to automate diagnosing patients with respiratory illnesses based on their breathing patterns. However, these models do not consider the demographic biases,…

Machine Learning · Computer Science 2025-01-10 Rachel Pfeifer , Sudip Vhaduri , James Eric Dietz

Early detection of lung nodules with computed tomography (CT) is critical for the longer survival of lung cancer patients and better quality of life. Computer-aided detection/diagnosis (CAD) is proven valuable as a second or concurrent…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Chuang Niu , Ge Wang

High-performing out-of-distribution (OOD) detection, both anomaly and novel class, is an important prerequisite for the practical use of classification models. In this paper, we focus on the species recognition task in images concerned with…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 L. E. Hogeweg , R. Gangireddy , D. Brunink , V. J. Kalkman , L. Cornelissen , J. W. Kamminga

Computer-aided diagnosis for low-dose computed tomography (CT) based on deep learning has recently attracted attention as a first-line automatic testing tool because of its high accuracy and low radiation exposure. However, existing methods…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Kyung-Su Kim , Seong Je Oh , Ju Hwan Lee , Myung Jin Chung

Detecting out-of-distribution (OOD) samples in medical imaging plays an important role for downstream medical diagnosis. However, existing OOD detectors are demonstrated on natural images composed of inter-classes and have difficulty…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Xiaoyuan Guo , Judy Wawira Gichoya , Saptarshi Purkayastha , Imon Banerjee

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

Despite the potential of weakly supervised learning to automatically annotate massive amounts of data, little is known about its limitations for use in computer-aided diagnosis (CAD). For CT specifically, interpreting the performance of CAD…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Fakrul Islam Tushar , Vincent M. D'Anniballe , Geoffrey D. Rubin , Ehsan Samei , Joseph Y. Lo

Applying machine learning to real-world medical data, e.g. from hospital archives, has the potential to revolutionize disease detection in brain images. However, detecting pathology in such heterogeneous cohorts is a difficult challenge.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Ana Lawry Aguila , Ayodeji Ijishakin , Juan Eugenio Iglesias , Tomomi Takenaga , Yukihiro Nomura , Takeharu Yoshikawa , Osamu Abe , Shouhei Hanaoka

Income inequality is a major contributor to health disparities, yet its effects often vary by geography and are commonly represented as compositional distributions (e.g., proportions of households across income brackets). Existing spatial…

Methodology · Statistics 2026-05-18 Jingwen Deng , Shujie Ma , Sergio J. Rey , Guanyu Hu

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality. While COPD diagnosis is based on lung function tests, early stages and progression of different aspects of the disease can be visible and…

Image and Video Processing · Electrical Eng. & Systems 2019-09-30 Max Argus , Cornelia Schaefer-Prokop , David A. Lynch , Bram van Ginneken

Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…

Quantitative Methods · Quantitative Biology 2026-03-09 P. Bilha Githinji , Xi Yuan , Ijaz Gul , Lian Zhang , Jinhao Xu , Zhenglin Chen , Peiwu Qin , Dongmei Yu

Chronic respiratory diseases, such as chronic obstructive pulmonary disease and asthma, are a serious health crisis, affecting a large number of people globally and inflicting major costs on the economy. Current methods for assessing the…

Image and Video Processing · Electrical Eng. & Systems 2021-04-06 Rohan Tan Bhowmik

Weakly supervised disease classification of CT imaging suffers from poor localization owing to case-level annotations, where even a positive scan can hold hundreds to thousands of negative slices along multiple planes. Furthermore, although…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Anindo Saha , Fakrul I. Tushar , Khrystyna Faryna , Vincent M. D'Anniballe , Rui Hou , Maciej A. Mazurowski , Geoffrey D. Rubin , Joseph Y. Lo

Chest radiography is an effective screening tool for diagnosing pulmonary diseases. In computer-aided diagnosis, extracting the relevant region of interest, i.e., isolating the lung region of each radiography image, can be an essential step…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Hilda Azimi , Jianxing Zhang , Pengcheng Xi , Hala Asad , Ashkan Ebadi , Stephane Tremblay , Alexander Wong

We aim to optimize the binary detection of Chronic Obstructive Pulmonary Disease (COPD) based on emphysema presence in the lung with convolutional neural networks (CNN) by exploring manually adjusted versus automated window-setting…

Accurate classification of lung diseases from chest CT scans plays an important role in computer-aided diagnosis systems. However, medical imaging datasets often suffer from severe class imbalance, which may significantly degrade the…

Image and Video Processing · Electrical Eng. & Systems 2026-03-18 Kejin Lu , Jianfa Bai , Qingqiu Li , Runtian Yuan , Jilan Xu , Junlin Hou , Yuejie Zhang , Rui Feng

We present a comprehensive experimental study on pretrained feature extractors for visual out-of-distribution (OOD) detection, focusing on adapting contrastive language-image pretrained (CLIP) models. Without fine-tuning on the training…

Computer Vision and Pattern Recognition · Computer Science 2023-11-10 Nikolas Adaloglou , Felix Michels , Tim Kaiser , Markus Kollmann

Early detection of lung cancer is essential in reducing mortality. Recent studies have demonstrated the clinical utility of low-dose computed tomography (CT) to detect lung cancer among individuals selected based on very limited clinical…

Computer Vision and Pattern Recognition · Computer Science 2019-02-25 Jiachen Wang , Riqiang Gao , Yuankai Huo , Shunxing Bao , Yunxi Xiong , Sanja L. Antic , Travis J. Osterman , Pierre P. Massion , Bennett A. Landman

Chronic Obstructive Pulmonary Disease (COPD) is a serious and debilitating disease affecting millions around the world. Its early detection using non-invasive means could enable preventive interventions that improve quality of life and…

Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung condition characterized by airflow obstruction. Current diagnostic methods primarily rely on identifying prominent features in spirometry (Volume-Flow time series) to detect…

Machine Learning · Computer Science 2025-03-04 Shuhao Mei , Xin Li , Yuxi Zhou , Jiahao Xu , Yong Zhang , Yuxuan Wan , Shan Cao , Qinghao Zhao , Shijia Geng , Junqing Xie , Shengyong Chen , Shenda Hong