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The performance of learning-based algorithms improves with the amount of labelled data used for training. Yet, manually annotating data is particularly difficult for medical image segmentation tasks because of the limited expert…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Mélanie Gaillochet , Christian Desrosiers , Hervé Lombaert

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

Segmenting histology images into diagnostically relevant regions is imperative to support timely and reliable decisions by pathologists. To this end, computer-aided techniques have been proposed to delineate relevant regions in scanned…

Deep learning has been successfully applied to OCT segmentation. However, for data from different manufacturers and imaging protocols, and for different regions of interest (ROIs), it requires laborious and time-consuming data annotation…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Haoran Zhang , Jianlong Yang , Ce Zheng , Shiqing Zhao , Aili Zhang

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

Image and Video Processing · Electrical Eng. & Systems 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

Histopathology Whole Slide Image (WSI) analysis serves as the gold standard for clinical cancer diagnosis in the daily routines of doctors. To develop computer-aided diagnosis model for WSIs, previous methods typically employ Multi-Instance…

Computer Vision and Pattern Recognition · Computer Science 2024-10-21 Honglin Li , Yunlong Zhang , Pingyi Chen , Zhongyi Shui , Chenglu Zhu , Lin Yang

The automatic registration of differently stained whole slide images (WSIs) is crucial for improving diagnosis and prognosis by fusing complementary information emerging from different visible structures. It is also useful to quickly…

Image and Video Processing · Electrical Eng. & Systems 2024-05-22 Marek Wodzinski , Niccolò Marini , Manfredo Atzori , Henning Müller

Image segmentation is one of the most essential biomedical image processing problems for different imaging modalities, including microscopy and X-ray in the Internet-of-Medical-Things (IoMT) domain. However, annotating biomedical images is…

Computer Vision and Pattern Recognition · Computer Science 2021-01-25 Ziyuan Zhao , Zeng Zeng , Kaixin Xu , Cen Chen , Cuntai Guan

Semantic segmentation of satellite imagery plays a vital role in land cover mapping and environmental monitoring. However, annotating large-scale, high-resolution satellite datasets is costly and time consuming, especially when covering…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Gadi Hemanth Kumar , Athira Nambiar , Pankaj Bodani

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

Training object detectors with only image-level annotations is very challenging because the target objects are often surrounded by a large number of background clutters. Many existing approaches tackle this problem through object proposal…

Computer Vision and Pattern Recognition · Computer Science 2017-08-08 Wenhui Jiang , Thuyen Ngo , B. S. Manjunath , Zhicheng Zhao , Fei Su

Multi-task learning is central to many real-world applications. Unfortunately, obtaining labelled data for all tasks is time-consuming, challenging, and expensive. Active Learning (AL) can be used to reduce this burden. Existing techniques…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Nikita Durasov , Nik Dorndorf , Pascal Fua

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai

Active learning (AL) has found wide applications in medical image segmentation, aiming to alleviate the annotation workload and enhance performance. Conventional uncertainty-based AL methods, such as entropy and Bayesian, often rely on an…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Siteng Ma , Haochang Wu , Aonghus Lawlor , Ruihai Dong

When we can not assume a large amount of annotated data , active learning is a good strategy. It consists in learning a model on a small amount of annotated data (annotation budget) and in choosing the best set of points to annotate in…

Computer Vision and Pattern Recognition · Computer Science 2022-01-19 Umang Aggarwal , Adrian Popescu , Céline Hudelot

Delineation of cancerous regions in gigapixel whole slide images (WSIs) is a crucial diagnostic procedure in digital pathology. This process is time-consuming because of the large search space in the gigapixel WSIs, causing chances of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Hsien-Tzu Cheng , Chun-Fu Yeh , Po-Chen Kuo , Andy Wei , Keng-Chi Liu , Mong-Chi Ko , Kuan-Hua Chao , Yu-Ching Peng , Tyng-Luh Liu

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-03 Noriaki Hashimoto , Daisuke Fukushima , Ryoichi Koga , Yusuke Takagi , Kaho Ko , Kei Kohno , Masato Nakaguro , Shigeo Nakamura , Hidekata Hontani , Ichiro Takeuchi

Supervised deep learning requires a large amount of training samples with annotations (e.g. label class for classification task, pixel- or voxel-wised label map for segmentation tasks), which are expensive and time-consuming to obtain.…

Computer Vision and Pattern Recognition · Computer Science 2020-04-14 Yuanhan Mo , Shuo Wang , Chengliang Dai , Rui Zhou , Zhongzhao Teng , Wenjia Bai , Yike Guo

Current approaches for classification of whole slide images (WSI) in digital pathology predominantly utilize a two-stage learning pipeline. The first stage identifies areas of interest (e.g. tumor tissue), while the second stage processes…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 Marvin Teichmann , Andre Aichert , Hanibal Bohnenberger , Philipp Ströbel , Tobias Heimann

Methods to detect malignant lesions from screening mammograms are usually trained with fully annotated datasets, where images are labelled with the localisation and classification of cancerous lesions. However, real-world screening…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Yuanhong Chen , Yuyuan Liu , Chong Wang , Michael Elliott , Chun Fung Kwok , Carlos Pena-Solorzano , Yu Tian , Fengbei Liu , Helen Frazer , Davis J. McCarthy , Gustavo Carneiro
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