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From the simple measurement of tissue attributes in pathology workflow to designing an explainable diagnostic/prognostic AI tool, access to accurate semantic segmentation of tissue regions in histology images is a prerequisite. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Mostafa Jahanifar , Neda Zamani Tajeddin , Navid Alemi Koohbanani , Nasir Rajpoot

CNN visualization and interpretation methods, like class-activation maps (CAMs), are typically used to highlight the image regions linked to class predictions. These models allow to simultaneously classify images and extract class-dependent…

Computer Vision and Pattern Recognition · Computer Science 2020-11-17 Soufiane Belharbi , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Deep learning models have demonstrated great potential in medical 3D imaging, but their development is limited by the expensive, large volume of annotated data required. Active learning (AL) addresses this by training a model on a subset of…

Computational methods on analyzing Whole Slide Images (WSIs) enable early diagnosis and treatments by supporting pathologists in detection and classification of tumors. However, the extremely high resolution of WSIs makes end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Umar Marikkar , Muhammad Awais , Sara Atito

Automatic medical image segmentation plays a critical role in scientific research and medical care. Existing high-performance deep learning methods typically rely on large training datasets with high-quality manual annotations, which are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-17 Shanshan Wang , Cheng Li , Rongpin Wang , Zaiyi Liu , Meiyun Wang , Hongna Tan , Yaping Wu , Xinfeng Liu , Hui Sun , Rui Yang , Xin Liu , Jie Chen , Huihui Zhou , Ismail Ben Ayed , Hairong Zheng

Deep learning has been widely used to analyze digitized hematoxylin and eosin (H&E)-stained histopathology whole slide images. Automated cancer segmentation using deep learning can be used to diagnose malignancy and to find novel…

Image and Video Processing · Electrical Eng. & Systems 2022-03-30 David Joon Ho , M. Herman Chui , Chad M. Vanderbilt , Jiwon Jung , Mark E. Robson , Chan-Sik Park , Jin Roh , Thomas J. Fuchs

Histopathology image analysis is the golden standard of clinical diagnosis for Cancers. In doctors daily routine and computer-aided diagnosis, the Whole Slide Image (WSI) of histopathology tissue is used for analysis. Because of the…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Honglin Li , Yunlong Zhang , Chenglu Zhu , Jiatong Cai , Sunyi Zheng , Lin Yang

Throughout the world, breast cancer is one of the leading causes of female death. Recently, deep learning methods are developed to automatically grade breast cancer of histological slides. However, the performance of existing deep learning…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Yanyuet Man , Xiangyun Ding , Xingcheng Yao , Han Bao

Automated skin lesion analysis is very crucial in clinical practice, as skin cancer is among the most common human malignancy. Existing approaches with deep learning have achieved remarkable performance on this challenging task, however,…

Computer Vision and Pattern Recognition · Computer Science 2019-09-06 Xueying Shi , Qi Dou , Cheng Xue , Jing Qin , Hao Chen , Pheng-Ann Heng

In recent years, deep learning has become a breakthrough technique in assisting medical image diagnosis. Supervised learning using convolutional neural networks (CNN) provides state-of-the-art performance and has served as a benchmark for…

Image and Video Processing · Electrical Eng. & Systems 2023-06-30 Tao Wang , Xinlin Zhang , Yuanbo Zhou , Junlin Lan , Tao Tan , Min Du , Qinquan Gao , Tong Tong

Purpose: Manual annotations for training deep learning (DL) models in auto-segmentation are time-intensive. This study introduces a hybrid representation-enhanced sampling strategy that integrates both density and diversity criteria within…

Image and Video Processing · Electrical Eng. & Systems 2023-12-21 Ganping Li , Yoshito Otake , Mazen Soufi , Masashi Taniguchi , Masahide Yagi , Noriaki Ichihashi , Keisuke Uemura , Masaki Takao , Nobuhiko Sugano , Yoshinobu Sato

Active learning is considered a viable solution to alleviate the contradiction between the high dependency of deep learning-based segmentation methods on annotated data and the expensive pixel-level annotation cost of medical images.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Jun Shi , Shulan Ruan , Ziqi Zhu , Minfan Zhao , Hong An , Xudong Xue , Bing Yan

Active learning improves annotation efficiency by selecting the most informative samples for annotation and model training. While most prior work has focused on selecting informative images for classification tasks, we investigate the more…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Jingna Qiu , Frauke Wilm , Mathias Öttl , Jonas Utz , Maja Schlereth , Moritz Schillinger , Marc Aubreville , Katharina Breininger

Although active learning (AL) in segmentation tasks enables experts to annotate selected regions of interest (ROIs) instead of entire images, it remains highly challenging, labor-intensive, and cognitively demanding due to the blurry and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Md Shazid Islam , Shreyangshu Bera , Sudipta Paul , Amit K. Roy-Chowdhury

Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical…

Computer Vision and Pattern Recognition · Computer Science 2017-06-16 Lin Yang , Yizhe Zhang , Jianxu Chen , Siyuan Zhang , Danny Z. Chen

We propose a new method that employs transfer learning techniques to effectively correct sampling selection errors introduced by sparse annotations during supervised learning for automated tumor segmentation. The practicality of current…

Self-training has greatly facilitated domain adaptive semantic segmentation, which iteratively generates pseudo labels on unlabeled target data and retrains the network. However, realistic segmentation datasets are highly imbalanced, pseudo…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Binhui Xie , Longhui Yuan , Shuang Li , Chi Harold Liu , Xinjing Cheng

In this paper, we present a region-based pLSA model to accomplish the task of total scene annotation. To be more specific, we not only properly generate a list of tags for each image, but also localizing each region with its corresponding…

Computer Vision and Pattern Recognition · Computer Science 2013-11-25 Yuzhu Zhou , Le Li , Honggang Zhang

Multi-class cell segmentation in high-resolution gigapixel whole slide images (WSIs) is crucial for various clinical applications. However, training such models typically requires labor-intensive, pixel-wise annotations by domain experts.…

Deep learning methods have been shown to be effective for the automatic segmentation of structures and pathologies in medical imaging. However, they require large annotated datasets, whose manual segmentation is a tedious and time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2022-09-27 Bella Specktor Fadida , Daphna Link Sourani , Liat Ben Sira Elka Miller , Dafna Ben Bashat , Leo Joskowicz