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We introduce a new approach to functional causal modeling from observational data, called Causal Generative Neural Networks (CGNN). CGNN leverages the power of neural networks to learn a generative model of the joint distribution of the…

In applications, quantities of interest are often modelled in equilibrium or an equilibrium solution is sought. The presence of confounding makes causal inference in this setting challenging. We provide interpretable graphical models for…

Methodology · Statistics 2026-03-27 Kai Z. Teh , Kayvan Sadeghi , Terry Soo

COVID-19 has resulted in a public health global crisis. The pandemic control necessitates epidemic models that capture the trends and impacts on infectious individuals. Many exciting models can implement this but they lack practical…

Computers and Society · Computer Science 2021-04-13 Ou Deng , Kiichi Tago , Qun Jin

Research in transportation frequently involve modelling and predicting attributes of events that occur at regular intervals. The event could be arrival of a bus at a bus stop, the volume of a traffic at a particular point, the demand at a…

Machine Learning · Computer Science 2015-08-14 Narayanan U. Edakunni , Aditi Raghunathan , Abhishek Tripathi , John Handley , Fredric Roulland

Understanding disease-gene associations is essential for unravelling disease mechanisms and advancing diagnostics and therapeutics. Traditional approaches based on manual curation and literature review are labour-intensive and not scalable,…

Machine Learning · Computer Science 2026-02-24 Osman Onur Kuzucu , Tunca Doğan

The ongoing need for effective epidemic modeling has driven advancements in capturing the complex dynamics of infectious diseases. Traditional models, such as Susceptible-Infected-Recovered, and graph-based approaches often fail to account…

Social and Information Networks · Computer Science 2025-04-02 Songyuan Liu , Shengbo Gong , Tianning Feng , Zewen Liu , Max S. Y. Lau , Wei Jin

The reconstruction of missing information in epidemic spreading on contact networks can be essential in the prevention and containment strategies. The identification and warning of infectious but asymptomatic individuals (i.e., contact…

Social and Information Networks · Computer Science 2022-11-21 Indaco Biazzo , Alfredo Braunstein , Luca Dall'Asta , Fabio Mazza

Graph neural networks (GNNs) learn the representation of graph-structured data, and their expressiveness can be further enhanced by inferring node relations for propagation. Attention-based GNNs infer neighbor importance to manipulate the…

Machine Learning · Computer Science 2023-06-06 Soo Yong Lee , Fanchen Bu , Jaemin Yoo , Kijung Shin

Agent Based Models (ABMs) have emerged as a powerful tool for investigating complex social interactions, particularly in the context of public health and infectious disease investigation. In an effort to enhance the conventional ABM,…

Multiagent Systems · Computer Science 2024-03-12 Sijin Zhang , Alvaro Orsi , Lei Chen

Epidemiological models may give some basic guidelines for public health practitioners, allowing to analyze issues that can influence the strategies to prevent and fight a disease. To be used in decision-making, however, a mathematical model…

Populations and Evolution · Quantitative Biology 2013-08-15 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

Multimodal brain networks characterize complex connectivities among different brain regions from both structural and functional aspects and provide a new means for mental disease analysis. Recently, Graph Neural Networks (GNNs) have become…

Neurons and Cognition · Quantitative Biology 2022-05-25 Yanqiao Zhu , Hejie Cui , Lifang He , Lichao Sun , Carl Yang

Most previous studies on multi-agent reinforcement learning focus on deriving decentralized and cooperative policies to maximize a common reward and rarely consider the transferability of trained policies to new tasks. This prevents such…

Machine Learning · Computer Science 2019-11-28 Heechang Ryu , Hayong Shin , Jinkyoo Park

Networks are models representing relationships between entities. Often these relationships are explicitly given, or we must learn a representation which generalizes and predicts observed behavior in underlying individual data (e.g.…

Social and Information Networks · Computer Science 2017-09-19 Ivan Brugere , Chris Kanich , Tanya Y. Berger-Wolf

Graph neural networks (GNNs) have been extensively studied for prediction tasks on graphs. As pointed out by recent studies, most GNNs assume local homophily, i.e., strong similarities in local neighborhoods. This assumption however limits…

Machine Learning · Computer Science 2021-10-04 Sean Li , Dongwoo Kim , Qing Wang

The lack of interpretability is an inevitable problem when using neural network models in real applications. In this paper, an explainable neural network based on generalized additive models with structured interactions (GAMI-Net) is…

Machine Learning · Statistics 2021-06-03 Zebin Yang , Aijun Zhang , Agus Sudjianto

Graph-based machine learning methods are useful tools in the identification and prediction of variation in genetic data. In particular, the comprehension of phenotypic effects at the cellular level is an accelerating research area in…

Quantitative Methods · Quantitative Biology 2024-12-06 Nandini Gadhia , Michalis Smyrnakis , Po-Yu Liu , Damer Blake , Melanie Hay , Anh Nguyen , Dominic Richards , Dong Xia , Ritesh Krishna

We present a technique to characterize differentially expressed genes in terms of their position in a high-dimensional co-expression network. The set-up of Gaussian graphical models is used to construct representations of the co-expression…

Applications · Statistics 2010-11-17 Gabriel C. G. de Abreu , Rodrigo Labouriau

Individual-based models of contagious processes are useful for predicting epidemic trajectories and informing intervention strategies. In such models, the incorporation of contact network information can capture the non-randomness and…

Populations and Evolution · Quantitative Biology 2023-11-09 Maxwell H. Wang , Jukka-Pekka Onnela

Many real world network problems often concern multivariate nodal attributes such as image, textual, and multi-view feature vectors on nodes, rather than simple univariate nodal attributes. The existing graph estimation methods built on…

Machine Learning · Statistics 2013-04-23 Mladen Kolar , Han Liu , Eric P. Xing

The exploration of epidemic dynamics on dynamically evolving ("adaptive") networks poses nontrivial challenges to the modeler, such as the determination of a small number of informative statistics of the detailed network state (that is, a…

Quantitative Methods · Quantitative Biology 2015-07-07 Assimakis A. Kattis , Alexander Holiday , Ana-Andreea Stoica , Ioannis G. Kevrekidis