English
Related papers

Related papers: Distilling Large Language Models for Biomedical Kn…

200 papers

Deploying large language models (LLMs) is challenging because they are memory inefficient and compute-intensive for practical applications. In reaction, researchers train smaller task-specific models by either finetuning with human labels…

Computation and Language · Computer Science 2023-07-06 Cheng-Yu Hsieh , Chun-Liang Li , Chih-Kuan Yeh , Hootan Nakhost , Yasuhisa Fujii , Alexander Ratner , Ranjay Krishna , Chen-Yu Lee , Tomas Pfister

Large language models (LLMs) are increasingly recognized as valuable tools across the medical environment, supporting clinical, research, and administrative workflows. However, strict privacy and network security regulations in hospital…

Computation and Language · Computer Science 2026-01-09 Seokhwan Ko , Donghyeon Lee , Jaewoo Chun , Hyungsoo Han , Junghwan Cho

Large language models (LLMs) have demonstrated remarkable abilities in various natural language processing areas, but they demand high computation resources which limits their deployment in real-world. Distillation is one technique to solve…

Computation and Language · Computer Science 2025-07-31 Zhi Zhou , Sirui Miao , Xiangyu Duan , Hao Yang , Min Zhang

In real-world NLP applications, Large Language Models (LLMs) offer promising solutions due to their extensive training on vast datasets. However, the large size and high computation demands of LLMs limit their practicality in many…

Artificial Intelligence · Computer Science 2025-04-01 Juanhui Li , Sreyashi Nag , Hui Liu , Xianfeng Tang , Sheikh Sarwar , Limeng Cui , Hansu Gu , Suhang Wang , Qi He , Jiliang Tang

Knowledge distillation typically involves transferring knowledge from a Large Language Model (LLM) to a Smaller Language Model (SLM). However, in tasks such as text matching, fine-tuned smaller models often yield more effective…

Computation and Language · Computer Science 2025-07-09 Mingzhe Li , Jing Xiang , Qishen Zhang , Kaiyang Wan , Xiuying Chen

Large language models (LLMs) have recently demonstrated strong potential for autonomous vehicle motion planning by reformulating trajectory prediction as a language generation problem. However, deploying capable LLMs in resource-constrained…

Robotics · Computer Science 2026-04-10 Amirhossein Afsharrad , Amirhesam Abedsoltan , Ahmadreza Moradipari , Sanjay Lall

Pretrained language models like BERT have achieved good results on NLP tasks, but are impractical on resource-limited devices due to memory footprint. A large fraction of this footprint comes from the input embeddings with large input…

Computation and Language · Computer Science 2021-02-09 Sanqiang Zhao , Raghav Gupta , Yang Song , Denny Zhou

Clinical summarization is crucial in healthcare as it distills complex medical data into digestible information, enhancing patient understanding and care management. Large language models (LLMs) have shown significant potential in…

Computation and Language · Computer Science 2025-08-21 Anindya Bijoy Das , Shibbir Ahmed , Shahnewaz Karim Sakib

Large language models (LLMs) have demonstrated astonishing capabilities in natural language processing (NLP) tasks, sparking interest in their application to professional domains with higher specialized requirements. However, restricted…

Computation and Language · Computer Science 2024-05-09 Zheyan Qu , Lu Yin , Zitong Yu , Wenbo Wang , Xing zhang

Purpose: The performance of three different large language models (LLMS) (GPT-3.5, GPT-4, and PaLM2) in answering ophthalmology professional questions was evaluated and compared with that of three different professional populations (medical…

Computation and Language · Computer Science 2023-11-10 Jason Holmes , Shuyuan Ye , Yiwei Li , Shi-Nan Wu , Zhengliang Liu , Zihao Wu , Jinyu Hu , Huan Zhao , Xi Jiang , Wei Liu , Hong Wei , Jie Zou , Tianming Liu , Yi Shao

The recent success of large language models (LLMs) has paved the way for their adoption in the high-stakes domain of healthcare. Specifically, the application of LLMs in patient-trial matching, which involves assessing patient eligibility…

Artificial Intelligence · Computer Science 2023-12-18 Mauro Nievas , Aditya Basu , Yanshan Wang , Hrituraj Singh

Background: Machine learning methods for clinical named entity recognition and entity normalization systems can utilize both labeled corpora and Knowledge Graphs (KGs) for learning. However, infrequently occurring concepts may have few…

Computation and Language · Computer Science 2024-10-11 Kuleen Sasse , Shinjitha Vadlakonda , Richard E. Kennedy , John D. Osborne

Knowledge Distillation (KD) is a critical tool for training Large Language Models (LLMs), yet the majority of research focuses on approaches that rely solely on output logits, neglecting semantic information in the teacher's intermediate…

Computation and Language · Computer Science 2026-05-13 Maxime Guigon , Lucas Dixon , Michaël E. Sander

Large Language Models (LLMs) have shown promising performance in knowledge-intensive reasoning tasks that require a compound understanding of knowledge. However, deployment of the LLMs in real-world applications can be challenging due to…

Computation and Language · Computer Science 2023-10-31 Minki Kang , Seanie Lee , Jinheon Baek , Kenji Kawaguchi , Sung Ju Hwang

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

In the era of Large Language Models (LLMs), Knowledge Distillation (KD) emerges as a pivotal methodology for transferring advanced capabilities from leading proprietary LLMs, such as GPT-4, to their open-source counterparts like LLaMA and…

Computation and Language · Computer Science 2024-10-22 Xiaohan Xu , Ming Li , Chongyang Tao , Tao Shen , Reynold Cheng , Jinyang Li , Can Xu , Dacheng Tao , Tianyi Zhou

Enhancing computational efficiency and reducing deployment costs for large language models (LLMs) have become critical challenges in various resource-constrained scenarios. In this work, we present DistilQwen2.5, a family of distilled,…

Computation and Language · Computer Science 2025-04-22 Chengyu Wang , Junbing Yan , Yuanhao Yue , Jun Huang

Proprietary large language models (LLMs) embody substantial economic value and are generally exposed only as black-box APIs, yet adversaries can still exploit their outputs to extract knowledge via distillation. Existing defenses focus…

Computation and Language · Computer Science 2026-05-07 Hao Fang , Tianyi Zhang , Tianqu Zhuang , Jiawei Kong , Kuofeng Gao , Bin Chen , Leqi Zheng , Shu-Tao Xia , Ke Xu

Large Language Models (LLMs) demonstrate remarkable versatility in various NLP tasks but encounter distinct challenges in biomedical due to the complexities of language and data scarcity. This paper investigates LLMs application in the…

Computation and Language · Computer Science 2024-07-12 Masoud Monajatipoor , Jiaxin Yang , Joel Stremmel , Melika Emami , Fazlolah Mohaghegh , Mozhdeh Rouhsedaghat , Kai-Wei Chang

Biomedical research is growing at such an exponential pace that scientists, researchers, and practitioners are no more able to cope with the amount of published literature in the domain. The knowledge presented in the literature needs to be…

Artificial Intelligence · Computer Science 2024-07-09 Nikola Milosevic , Wolfgang Thielemann