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The treatment of age-related macular degeneration (AMD) requires continuous eye exams using optical coherence tomography (OCT). The need for treatment is determined by the presence or change of disease-specific OCT-based biomarkers.…

Image and Video Processing · Electrical Eng. & Systems 2026-03-12 Timo Kepp , Helge Sudkamp , Claus von der Burchard , Hendrik Schenke , Peter Koch , Gereon Hüttmann , Johann Roider , Mattias P. Heinrich , Heinz Handels

The omnipresence of deep learning architectures such as deep convolutional neural networks (CNN)s is fueled by the synergistic combination of ever-increasing labeled datasets and specialized hardware. Despite the indisputable success, the…

Machine Learning · Statistics 2016-11-29 Meshia Cédric Oveneke , Mitchel Aliosha-Perez , Yong Zhao , Dongmei Jiang , Hichem Sahli

Computed Tomography (CT) is a non-invasive imaging modality with applications ranging from healthcare to security. It reconstructs cross-sectional images of an object using a collection of projection data collected at different angles.…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Muhammad Usman Ghani , W. Clem Karl

Computed tomography (CT) is an effective medical imaging modality, widely used in the field of clinical medicine for the diagnosis of various pathologies. Advances in Multidetector CT imaging technology have enabled additional…

Image and Video Processing · Electrical Eng. & Systems 2022-04-11 Abril Corona-Figueroa , Jonathan Frawley , Sam Bond-Taylor , Sarath Bethapudi , Hubert P. H. Shum , Chris G. Willcocks

Optical coherence tomography (OCT) is a non-invasive 3D modality widely used in ophthalmology for imaging the retina. Achieving automated, anatomically coherent retinal layer segmentation on OCT is important for the detection and monitoring…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Botond Fazekas , Guilherme Aresta , Dmitrii Lachinov , Sophie Riedl , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

We introduce Neural Optimal Design of Experiments, a learning-based framework for optimal experimental design in inverse problems that avoids classical bilevel optimization and indirect sparsity regularization. NODE jointly trains a neural…

Machine Learning · Computer Science 2026-01-08 John E. Darges , Babak Maboudi Afkham , Matthias Chung

Image reconstruction from insufficient data is common in computed tomography (CT), e.g., image reconstruction from truncated data, limited-angle data and sparse-view data. Deep learning has achieved impressive results in this field.…

Image and Video Processing · Electrical Eng. & Systems 2020-05-21 Yixing Huang , Alexander Preuhs , Michael Manhart , Guenter Lauritsch , Andreas Maier

Performing X-ray computed tomography (CT) examinations with less radiation has recently received increasing interest: in medical imaging this means less (potentially harmful) radiation for the patient; in non-destructive testing of…

Medical Physics · Physics 2018-09-25 Dragos Trinca , Eduard Libin

Computed Tomography (CT) is a medical imaging modality that can generate more informative 3D images than 2D X-rays. However, this advantage comes at the expense of more radiation exposure, higher costs, and longer acquisition time. Hence,…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Shuangqin Cheng , Qingliang Chen , Qiyi Zhang , Ming Li , Yamuhanmode Alike , Kaile Su , Pengcheng Wen

Image segmentation plays a pivotal role in several medical-imaging applications by assisting the segmentation of the regions of interest. Deep learning-based approaches have been widely adopted for semantic segmentation of medical data. In…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Abhishek Shivdeo , Rohit Lokwani , Viraj Kulkarni , Amit Kharat , Aniruddha Pant

We present a method for selecting valuable projections in computed tomography (CT) scans to enhance image reconstruction and diagnosis. The approach integrates two important factors, projection-based detectability and data completeness,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-22 Linda-Sophie Schneider , Mareike Thies , Christopher Syben , Richard Schielein , Mathias Unberath , Andreas Maier

X-ray computed tomography (CT) is a widely used imaging technique that provides detailed examinations into the internal structure of an object with synchrotron CT (SR-CT) enabling improved data quality by using higher energy, monochromatic…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Austin Yunker , Peter Kenesei , Hemant Sharma , Jun-Sang Park , Antonino Miceli , Rajkumar Kettimuthu

Limited-angle X-ray tomography reconstruction is an ill-conditioned inverse problem in general. Especially when the projection angles are limited and the measurements are taken in a photon-limited condition, reconstructions from classical…

Image and Video Processing · Electrical Eng. & Systems 2021-12-21 Zhen Guo , Jung Ki Song , George Barbastathis , Michael E. Glinsky , Courtenay T. Vaughan , Kurt W. Larson , Bradley K. Alpert , Zachary H. Levine

Sparse-view Computed Tomography (CT) reconstructs images from a limited number of X-ray projections to reduce radiation and scanning time, which makes reconstruction an ill-posed inverse problem. Deep learning methods achieve high-fidelity…

Image and Video Processing · Electrical Eng. & Systems 2025-12-16 Aujasvit Datta , Jiayun Wang , Asad Aali , Armeet Singh Jatyani , Anima Anandkumar

Questions of `how best to acquire data' are essential to modeling and prediction in the natural and social sciences, engineering applications, and beyond. Optimal experimental design (OED) formalizes these questions and creates…

Methodology · Statistics 2026-05-01 Xun Huan , Jayanth Jagalur , Youssef Marzouk

Deep learning has been widely employed to solve the Electrical Impedance Tomography (EIT) image reconstruction problem. Most existing physical model-based and learning-based approaches focus on 2D EIT image reconstruction. However, when…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Zhaoguang Yi , Zhou Chen , Yunjie Yang

Deep learning has emerged as a powerful tool for solving inverse problems in imaging, including computed tomography (CT). However, most approaches require paired training data with ground truth images, which can be difficult to obtain,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Tatiana A. Bubba , Matteo Santacesaria , Andrea Sebastiani

Protocol optimization is critical in Computed Tomography (CT) to achieve high diagnostic image quality while minimizing radiation dose. However, due to the complex interdependencies among CT acquisition and reconstruction parameters,…

The development of fast and accurate image reconstruction algorithms is a central aspect of computed tomography. In this paper, we investigate this issue for the sparse data problem in photoacoustic tomography (PAT). We develop a direct and…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Stephan Antholzer , Markus Haltmeier , Johannes Schwab

Recently, compressed sensing (CS) computed tomography (CT) using sparse projection views has been extensively investigated to reduce the potential risk of radiation to patient. However, due to the insufficient number of projection views, an…

Computer Vision and Pattern Recognition · Computer Science 2016-11-28 Yo Seob Han , Jaejun Yoo , Jong Chul Ye