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There is a pressing need to better understand how microbial populations respond to antimicrobial drugs, and to find mechanisms to possibly eradicate antimicrobial-resistant cells. The inactivation of antimicrobials by resistant microbes can…

Populations and Evolution · Quantitative Biology 2023-11-16 Lluís Hernández-Navarro , Matthew Asker , Alastair M. Rucklidge , Mauro Mobilia

Environmental changes greatly influence the evolution of populations. Here, we study the dynamics of a population of two strains, one growing slightly faster than the other, competing for resources in a time-varying binary environment…

Populations and Evolution · Quantitative Biology 2020-07-28 Ami Taitelbaum , Robert West , Michael Assaf , Mauro Mobilia

Environment plays a fundamental role in the competition for resources, and hence in the evolution of populations. Here, we study a well-mixed, finite population consisting of two strains competing for the limited resources provided by an…

Populations and Evolution · Quantitative Biology 2017-10-16 Karl Wienand , Erwin Frey , Mauro Mobilia

Environmental variations can significantly influence how populations compete for resources, and hence shape their evolution. Here, we study population dynamics subject to a fluctuating environment modeled by a varying carrying capacity…

Populations and Evolution · Quantitative Biology 2023-04-14 Ami Taitelbaum , Robert West , Mauro Mobilia , Michael Assaf

Microorganisms live in environments that inevitably fluctuate between mild and harsh conditions. As harsh conditions may cause extinctions, the rate at which fluctuations occur can shape microbial communities and their diversity, but we…

Populations and Evolution · Quantitative Biology 2021-10-14 Shota Shibasaki , Mauro Mobilia , Sara Mitri

Antimicrobial resistance to drugs (AMR), a global threat to human and animal health, is often regarded as resulting from cooperative behaviour. Moreover, microbes generally evolve in volatile environments that, together with demographic…

Populations and Evolution · Quantitative Biology 2024-06-18 Lluís Hernández-Navarro , Matthew Asker , Mauro Mobilia

Environmental variability greatly influences the eco-evolutionary dynamics of a population, i.e. it affects how its size and composition evolve. Here, we study a well-mixed population of finite and fluctuating size whose growth is limited…

Populations and Evolution · Quantitative Biology 2021-10-14 Karl Wienand , Erwin Frey , Mauro Mobilia

The dynamics of two competing species in a finite size community is one of the most studied problems in population genetics and community ecology. Stochastic fluctuations lead, inevitably, to the extinction of one of the species, but the…

Populations and Evolution · Quantitative Biology 2016-11-30 Matan Danino , David A. Kessler , Nadav M. Shnerb

Microbes providing public goods are widespread in nature despite running the risk of being exploited by free-riders. However, the precise ecological factors supporting cooperation are still puzzling. Following recent experiments, we…

Populations and Evolution · Quantitative Biology 2012-03-28 Jonas Cremer , Anna Melbinger , Erwin Frey

Environmental fluctuations have important consequences in the organization of ecological communities, and understanding how such a variability influences the biodiversity of an ecosystem is a major question in ecology. In this paper, we…

Populations and Evolution · Quantitative Biology 2016-11-16 Jorge Hidalgo , Samir Suweis , Amos Maritan

Individuals within any species exhibit differences in size, developmental state, or spatial location. These differences coupled with environmental fluctuations in demographic rates can have subtle effects on population persistence and…

Populations and Evolution · Quantitative Biology 2015-12-16 Gregory Roth , Sebastian J. Schreiber

Living species, ranging from bacteria to animals, exist in environmental conditions that exhibit spatial and temporal heterogeneity which requires them to adapt. Risk-spreading through spontaneous phenotypic variations is a known concept in…

Populations and Evolution · Quantitative Biology 2020-04-03 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

Understanding under what conditions interacting populations, whether they be plants, animals, or viral particles, coexist is a question of theoretical and practical importance in population biology. Both biotic interactions and…

Populations and Evolution · Quantitative Biology 2011-04-26 Sebastian J. Schreiber , Michel Benaïm , Kolawolé A. S. Atchadé

The impact of environmental fluctuation on species diversity is studied with a model of the evolutionary ecology of microorganisms. We show that environmental fluctuation induces evolutionary branching and assures the consequential…

Populations and Evolution · Quantitative Biology 2015-05-13 Masashi Tachikawa

Microbial communities routinely have several possible species compositions or community states observed for the same environmental parameters. Changes in these parameters can trigger abrupt and persistent transitions (regime shifts) between…

Populations and Evolution · Quantitative Biology 2019-07-03 Veronika Dubinkina , Yulia Fridman , Parth Pratim Pandey , Sergei Maslov

Microbial communities harbor extensive fine-scale diversity: closely-related strains of the same species coexist alongside many distantly-related taxa. Yet strain coexistence remains poorly understood, largely because most studies neglect…

Populations and Evolution · Quantitative Biology 2026-03-17 Naven Narayanan Venkatanarayanan , Akshit Goyal

Ecosystems, which are intricate amalgams of biological communities and their surrounding environments, continually evolve under the influence of their myriad interactions. The world is currently facing intensifying environmental…

Biological Physics · Physics 2023-11-23 Ikumi Kobayashi

Understanding why strains with different metabolic pathways that compete for a single limiting resource coexist is a challenging issue within a theoretical perspective. Previous investigations rely on mechanisms such as group or spatial…

Populations and Evolution · Quantitative Biology 2016-06-29 Lenin Fernández , André Amado , Fernando Fagundes Ferreira , Paulo R. A. Campos

Ecology and evolution under changing environments are important in many subfields of biology with implications for medicine. Here, we explore an example: the consequences of fluctuating environments on the emergence of antibiotic…

Populations and Evolution · Quantitative Biology 2021-04-13 Bryce Morsky , Dervis Can Vural

A fundamental goal of microbial ecology is to understand what determines the diversity, stability, and structure of microbial ecosystems. The microbial context poses special conceptual challenges because of the strong mutual influences…

Biological Physics · Physics 2019-03-06 Robert Marsland , Wenping Cui , Joshua Goldford , Alvaro Sanchez , Kirill Korolev , Pankaj Mehta
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