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Given the crucial role of microtubules for cell survival, many researchers have found success using microtubule-targeting agents in the search for effective cancer therapeutics. Understanding microtubule responses to targeted interventions…

Image and Video Processing · Electrical Eng. & Systems 2019-10-03 Hao-Chih Lee , Sarah T Cherng , Riccardo Miotto , Joel T Dudley

Modern Imaging Atmospheric Cherenkov Telescopes (IACTs) generate a huge amount of data that must be classified automatically, ideally in real time. Currently, machine learning-based solutions are increasingly being used to solve…

Instrumentation and Methods for Astrophysics · Physics 2025-04-03 Yu. Yu. Dubenskaya , A. P. Kryukov , E. O. Gres , S. P. Polyakov , E. B. Postnikov , P. A. Volchugov , A. A. Vlaskina , D. P. Zhurov

Automated lesion segmentation from computed tomography (CT) is an important and challenging task in medical image analysis. While many advancements have been made, there is room for continued improvements. One hurdle is that CT images can…

Computer Vision and Pattern Recognition · Computer Science 2018-07-20 Youbao Tang , Jinzheng Cai , Le Lu , Adam P. Harrison , Ke Yan , Jing Xiao , Lin Yang , Ronald M. Summers

In digital pathology, the spatial context of cells is important for cell classification, cancer diagnosis and prognosis. To model such complex cell context, however, is challenging. Cells form different mixtures, lineages, clusters and…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Shahira Abousamra , Rajarsi Gupta , Tahsin Kurc , Dimitris Samaras , Joel Saltz , Chao Chen

As a new emerging and promising type of generative models, diffusion models have proven to outperform Generative Adversarial Networks (GANs) in multiple tasks, including image synthesis. In this work, we explore semantic image synthesis for…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Yan Zhuang , Benjamin Hou , Tejas Sudharshan Mathai , Pritam Mukherjee , Boah Kim , Ronald M. Summers

Modern optical microscopes are fully motorised; however, transforming them into truly smart systems requires real-time adjustment of acquisition settings in response to detected objects and dynamic biological events. At the core are…

Current state-of-the-art photorealistic generators are computationally expensive, involve unstable training processes, and have real and synthetic distributions that are dissimilar in higher-dimensional spaces. To solve these issues, we…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 Badr Belhiti , Justin Milushev , Avinash Gupta , John Breedis , Johnson Dinh , Jesse Pisel , Michael Pyrcz

The development of clinical-grade artificial intelligence in pathology is limited by the scarcity of diverse, high-quality annotated datasets. Generative models offer a potential solution but suffer from semantic instability and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Xianchao Guan , Zhiyuan Fan , Yifeng Wang , Fuqiang Chen , Yanjiang Zhou , Zengyang Che , Hongxue Meng , Xin Li , Yaowei Wang , Hongpeng Wang , Min Zhang , Heng Tao Shen , Zheng Zhang , Yongbing Zhang

Synthetic medical image generation has a huge potential for improving healthcare through many applications, from data augmentation for training machine learning systems to preserving patient privacy. Conditional Adversarial Generative…

Image and Video Processing · Electrical Eng. & Systems 2022-05-05 Mohammad Havaei , Ximeng Mao , Yiping Wang , Qicheng Lao

With the advancement of modern medicine and the development of technologies such as MRI, CT, and cellular analysis, it has become increasingly critical for clinicians to accurately interpret various diagnostic images. However, modern…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Ruiming Min , Minghao Liu

Image generation has raised tremendous attention in both academic and industrial areas, especially for the conditional and target-oriented image generation, such as criminal portrait and fashion design. Although the current studies have…

Computer Vision and Pattern Recognition · Computer Science 2021-12-07 Songyao Jiang , Hongfu Liu , Yue Wu , Yun Fu

Conditional image generation is the task of generating diverse images using class label information. Although many conditional Generative Adversarial Networks (GAN) have shown realistic results, such methods consider pairwise relations…

Computer Vision and Pattern Recognition · Computer Science 2021-02-04 Minguk Kang , Jaesik Park

In this work, we propose a few-shot colorectal tissue image generation method for addressing the scarcity of histopathological training data for rare cancer tissues. Our few-shot generation method, named XM-GAN, takes one base and a pair of…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Amandeep Kumar , Ankan kumar Bhunia , Sanath Narayan , Hisham Cholakkal , Rao Muhammad Anwer , Jorma Laaksonen , Fahad Shahbaz Khan

Cellular composition prediction, i.e., predicting the presence and counts of different types of cells in the tumor microenvironment from a digitized image of a Hematoxylin and Eosin (H&E) stained tissue section can be used for various tasks…

Quantitative Methods · Quantitative Biology 2021-08-27 Muhammad Dawood , Kim Branson , Nasir M. Rajpoot , Fayyaz ul Amir Afsar Minhas

Purpose: The objective of this work is to introduce an advanced framework designed to enhance ultrasound images, especially those captured by portable hand-held devices, which often produce lower quality images due to hardware constraints.…

Image and Video Processing · Electrical Eng. & Systems 2024-12-19 Shreeram Athreya , Ashwath Radhachandran , Vedrana Ivezić , Vivek Sant , Corey W. Arnold , William Speier

Novel multimodal imaging methods are capable of generating extensive, super high resolution datasets for preclinical research. Yet, a massive lack of annotations prevents the broad use of deep learning to analyze such data. So far, existing…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Izabela Horvath , Johannes C. Paetzold , Oliver Schoppe , Rami Al-Maskari , Ivan Ezhov , Suprosanna Shit , Hongwei Li , Ali Ertuerk , Bjoern H. Menze

This work proposes the continuous conditional generative adversarial network (CcGAN), the first generative model for image generation conditional on continuous, scalar conditions (termed regression labels). Existing conditional GANs (cGANs)…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Xin Ding , Yongwei Wang , Zuheng Xu , William J. Welch , Z. Jane Wang

In this paper, we aim at solving the multi-domain image-to-image translation problem with a unified model in an unsupervised manner. The most successful work in this area refers to StarGAN, which works well in tasks like face attribute…

Computer Vision and Pattern Recognition · Computer Science 2019-01-17 Xiao Liu , Shengchuan Zhang , Hong Liu , Xin Liu , Cheng Deng , Rongrong Ji

Automated synthesis of histology images has several potential applications in computational pathology. However, no existing method can generate realistic tissue images with a bespoke cellular layout or user-defined histology parameters. In…

Image and Video Processing · Electrical Eng. & Systems 2022-12-29 Srijay Deshpande , Muhammad Dawood , Fayyaz Minhas , Nasir Rajpoot

There is a significant need for the generation of virtual histological information from coronary optical coherence tomography (OCT) images to better guide the treatment of coronary artery disease. However, existing methods either require a…

Image and Video Processing · Electrical Eng. & Systems 2023-07-25 Xueshen Li , Hongshan Liu , Xiaoyu Song , Brigitta C. Brott , Silvio H. Litovsky , Yu Gan
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