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Academic advances of AI models in high-precision domains, like healthcare, need to be made explainable in order to enhance real-world adoption. Our past studies and ongoing interactions indicate that medical experts can use AI systems with…

Many diseases, including cancer and chronic conditions, require extended treatment periods and long-term strategies. Machine learning and AI research focusing on electronic health records (EHRs) have emerged to address this need. Effective…

Objective: Create precise, structured, data-backed guidelines for type 2 diabetes treatment progression, suitable for clinical adoption. Research Design and Methods: Our training cohort was composed of patient (with type 2 diabetes) visits…

Artificial Intelligence · Computer Science 2025-04-18 Dewang Kumar Agarwal , Dimitris J. Bertsimas

Diabetic retinopathy is one of the most threatening complications of diabetes that leads to permanent blindness if left untreated. One of the essential challenges is early detection, which is very important for treatment success.…

Machine Learning · Computer Science 2020-03-06 Borys Tymchenko , Philip Marchenko , Dmitry Spodarets

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Deep learning has excelled in medical image classification, but its clinical application is limited by poor interpretability. Capsule networks, known for encoding hierarchical relationships and spatial features, show potential in addressing…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Xinyu Geng , Jiaming Wang , Jun Xu

Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and…

Quantitative Methods · Quantitative Biology 2019-11-11 Devin Taylor , Simeon Spasov , Pietro Liò

Automatic classification of diabetic retinopathy from retinal images has been widely studied using deep neural networks with impressive results. However, there is a clinical need for estimation of the uncertainty in the classifications, a…

Computer Vision and Pattern Recognition · Computer Science 2022-02-03 Joel Jaskari , Jaakko Sahlsten , Theodoros Damoulas , Jeremias Knoblauch , Simo Särkkä , Leo Kärkkäinen , Kustaa Hietala , Kimmo Kaski

Artificial intelligence (AI) will pave the way to a new era in medicine. However, currently available AI systems do not interact with a patient, e.g., for anamnesis, and thus are only used by the physicians for predictions in diagnosis or…

Computers and Society · Computer Science 2019-08-29 Sebastian Spänig , Agnes Emberger-Klein , Jan-Peter Sowa , Ali Canbay , Klaus Menrad , Dominik Heider

Biomedical association studies are increasingly done using clinical concepts, and in particular diagnostic codes from clinical data repositories as phenotypes. Clinical concepts can be represented in a meaningful, vector space using word…

Quantitative Methods · Quantitative Biology 2018-11-06 Brett K. Beaulieu-Jones , Isaac S. Kohane , Andrew L. Beam

Celiac disease prevalence and diagnosis have increased substantially in recent years. The current gold standard for celiac disease confirmation is visual examination of duodenal mucosal biopsies. An accurate computer-aided biopsy analysis…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Jason W. Wei , Jerry W. Wei , Christopher R. Jackson , Bing Ren , Arief A. Suriawinata , Saeed Hassanpour

Deep learning excels in the analysis of unstructured data and recent advancements allow to extend these techniques to survival analysis. In the context of clinical radiology, this enables, e.g., to relate unstructured volumetric images to a…

Machine Learning · Computer Science 2021-11-04 Tobias Weber , Michael Ingrisch , Matthias Fabritius , Bernd Bischl , David Rügamer

Healthcare sector is totally different from other industry. It is on high priority sector and people expect highest level of care and services regardless of cost. It did not achieve social expectation even though it consume huge percentage…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Muhammad Imran Razzak , Saeeda Naz , Ahmad Zaib

Identifying relationships between molecular variations and their clinical presentations has been challenged by the heterogeneous causes of a disease. It is imperative to unveil the relationship between the high dimensional molecular…

Methodology · Statistics 2021-09-02 Wennan Chang , Changlin Wan , Yong Zang , Chi Zhang , Sha Cao

Deep learning has introduced several learning-based methods to recognize breast tumours and presents high applicability in breast cancer diagnostics. It has presented itself as a practical installment in Computer-Aided Diagnostic (CAD)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Timothy Kwong , Samaneh Mazaheri

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Quantitative Methods · Quantitative Biology 2022-08-31 Mara Graziani , Niccolò Marini , Nicolas Deutschmann , Nikita Janakarajan , Henning Müller , María Rodríguez Martínez

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from conventional approaches may not be…

Applications · Statistics 2023-09-28 Lingsong Meng , Zhiguang Huo

We present deep significance clustering (DICE), a framework for jointly performing representation learning and clustering for "outcome-aware" stratification. DICE is intended to generate cluster membership that may be used to categorize a…

Machine Learning · Computer Science 2021-01-08 Yufang Huang , Kelly M. Axsom , John Lee , Lakshminarayanan Subramanian , Yiye Zhang

Precise and timely forecasting of blood glucose levels is essential for effective diabetes management. While extensive research has been conducted on Type 1 diabetes mellitus, Type 2 diabetes mellitus (T2DM) presents unique challenges due…

Computational Engineering, Finance, and Science · Computer Science 2024-09-12 Yuyang Sun , Panagiotis Kosmas

Embedding the nodes of a large network into an Euclidean space is a common objective in modern machine learning, with a variety of tools available. These embeddings can then be used as features for tasks such as community detection/node…

Machine Learning · Statistics 2024-10-23 Andrew Davison , S. Carlyle Morgan , Owen G. Ward
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