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Systems of linear equations are employed almost universally across a wide range of disciplines, from physics and engineering to biology, chemistry and statistics. Traditional solution methods such as Gaussian elimination become very time…

Quantum Physics · Physics 2019-01-23 Michael L Rogers , Robert L Singleton

A promising approach to solving hard binary optimisation problems is quantum adiabatic annealing (QA) in a transverse magnetic field. An instantaneous ground state --- initially a symmetric superposition of all possible assignments of $N$…

Quantum Physics · Physics 2016-05-18 Sergey Knysh

In this paper we describe a quantum algorithm to solve sparse systems of nonlinear differential equations whose nonlinear terms are polynomials. The algorithm is nondeterministic and its expected resource requirements are polylogarithmic in…

Quantum Physics · Physics 2008-12-24 Sarah K. Leyton , Tobias J. Osborne

In real-life applications, most optimization problems are variants of well-known combinatorial optimization problems, including additional constraints to fit with a particular use case. Usually, efficient algorithms to handle a restricted…

Discrete Mathematics · Computer Science 2025-01-24 Sébastien Martin , Pierre Bauguion , Youcef Magnouche , Jérémie Leguay

In this article, we describe an algorithm for solving Quadratic Unconstrained Binary Optimization problems on the Intel Loihi 2 neuromorphic processor. The solver is based on a hardware-aware fine-grained parallel simulated annealing…

Neural and Evolutionary Computing · Computer Science 2024-08-07 Alessandro Pierro , Philipp Stratmann , Gabriel Andres Fonseca Guerra , Sumedh Risbud , Timothy Shea , Ashish Rao Mangalore , Andreas Wild

The classical method to solve a quadratic optimization problem with nonlinear equality constraints is to solve the Karush-Kuhn-Tucker (KKT) optimality conditions using Newton's method. This approach however is usually computationally…

Optimization and Control · Mathematics 2016-03-17 Tuan T. Nguyen , Mircea Lazar , Hans Butler

The intersection between quantum computing and optimisation has been an area of interest in recent years. There have been numerous studies exploring the application of quantum and quantum-hybrid solvers to various optimisation problems.…

Quantum Physics · Physics 2024-05-29 Mayowa Ayodele

Conformation generation, also known as molecular unfolding (MU), is a crucial step in structure-based drug design, remaining a challenging combinatorial optimization problem. Quantum annealing (QA) has shown great potential for solving…

We investigate the use of quantum computing algorithms on real quantum hardware to tackle the computationally intensive task of feature selection for light-weight medical image datasets. Feature selection is often formulated as a k of n…

Quantum Physics · Physics 2025-02-27 Merlin A. Nau , Luca A. Nutricati , Bruno Camino , Paul A. Warburton , Andreas K. Maier

We present a hybrid classical-quantum framework based on the Frank-Wolfe algorithm, Q-FW, for solving quadratic, linearly-constrained, binary optimization problems on quantum annealers (QA). The computational premise of quantum computers…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Alp Yurtsever , Tolga Birdal , Vladislav Golyanik

In this work, we develop new pulse designs and embedding strategies to improve the analog quantum subroutines of hybrid column generation (CG) algorithms based on neutral-atoms quantum computers (NAQCs). These strategies are designed to…

Quantum Physics · Physics 2026-03-02 Cédrick Perron , Yves Bérubé-Lauzière , Victor Drouin-Touchette

A novel orthogonalization-free method together with two specific algorithms are proposed to solve extreme eigenvalue problems. On top of gradient-based algorithms, the proposed algorithms modify the multi-column gradient such that earlier…

Numerical Analysis · Mathematics 2021-10-15 Weiguo Gao , Yingzhou Li , Bichen Lu

In this paper, we propose a novel mixed integer programming model to formulate integrated operating room planning and scheduling problems, where several mandatory and elective surgeries are to be assigned and scheduled in operating rooms on…

Optimization and Control · Mathematics 2026-04-28 Mahdi Dolatkhah , Hossein Hashemi Doulabi , Walter Rei , Michel Gendreau

Here we explore which heuristic quantum algorithms for combinatorial optimization might be most practical to try out on a small fault-tolerant quantum computer. We compile circuits for several variants of quantum accelerated simulated…

A black-box optimization algorithm such as Bayesian optimization finds extremum of an unknown function by alternating inference of the underlying function and optimization of an acquisition function. In a high-dimensional space, such…

Quantum Physics · Physics 2021-05-03 Syun Izawa , Koki Kitai , Shu Tanaka , Ryo Tamura , Koji Tsuda

To solve tiling puzzles, such as "pentomino" or "tetromino" puzzles, we need to find the correct solutions out of numerous combinations of rotations or piece locations. Solving this kind of combinatorial optimization problem is a very…

Quantum Physics · Physics 2019-04-04 Asa Eagle , Takumi Kato , Yuichiro Minato

We analyze the performance of quantum annealing as a heuristic optimization method to find the absolute minimum of various continuous models, including landscapes with only two wells and also models with many competing minima and with…

Statistical Mechanics · Physics 2015-11-25 E. M. Inack , S. Pilati

In this paper, we study spline trajectory generation via the solution of two optimisation problems: (i) a quadratic program (QP) with linear equality constraints and (ii) a nonlinear and nonconvex optimisation program. We propose an…

Systems and Control · Electrical Eng. & Systems 2021-05-06 Declan Burke , Airlie Chapman , Iman Shames

This study combines simulated annealing with delta evaluation to solve the joint stratification and sample allocation problem. In this problem, atomic strata are partitioned into mutually exclusive and collectively exhaustive strata. Each…

Artificial Intelligence · Computer Science 2021-11-23 Mervyn O'Luing , Steven Prestwich , S. Armagan Tarim
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