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Mitotic count is the most important morphological feature of breast cancer grading. Many deep learning-based methods have been proposed but suffer from domain shift. In this work, we construct a Fourier-based segmentation model for mitosis…

Image and Video Processing · Electrical Eng. & Systems 2021-10-20 Sen Yang , Feng Luo , Jun Zhang , Xiyue Wang

Multi contrast MRI synthesis is inherently challenging due to the complex and nonlinear relationships among different contrasts. Each MRI contrast highlights unique tissue properties, but their complementary information is difficult to…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Sanuwani Dayarathna , Himashi Peiris , Kh Tohidul Islam , Tien-Tsin Wong , Zhaolin Chen

As medical diagnoses increasingly leverage multimodal data, machine learning models are expected to effectively fuse heterogeneous information while remaining robust to missing modalities. In this work, we propose a novel multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Yi Gu , Kuniaki Saito , Jiaxin Ma

In the surveillance and defense domain, multi-target detection and classification (MTD) is considered essential yet challenging due to heterogeneous inputs from diverse data sources and the computational complexity of algorithms designed…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Ngoc Tuyen Do , Tri Nhu Do

The single domain generalization(SDG) based on meta-learning has emerged as an effective technique for solving the domain-shift problem. However, the inadequate match of data distribution between source and augmented domains and difficult…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Can Sun , Hao Zheng , Zhigang Hu , Liu Yang , Meiguang Zheng , Bo Xu

Large-scale, big-variant, high-quality data are crucial for developing robust and successful deep-learning models for medical applications since they potentially enable better generalization performance and avoid overfitting. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Zheyuan Zhang , Lanhong Yao , Bin Wang , Debesh Jha , Gorkem Durak , Elif Keles , Alpay Medetalibeyoglu , Ulas Bagci

Empirical evaluation of breast tissue biopsies for mitotic nuclei detection is considered an important prognostic biomarker in tumor grading and cancer progression. However, automated mitotic nuclei detection poses several challenges…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Anabia Sohail , Muhammad Ahsan Mukhtar , Asifullah Khan , Muhammad Mohsin Zafar , Aneela Zameer , Saranjam Khan

Pathologist-defined labels are the gold standard for histopathological data sets, regardless of well-known limitations in consistency for some tasks. To date, some datasets on mitotic figures are available and were used for development of…

Computer Vision and Pattern Recognition · Computer Science 2020-10-22 Christof A. Bertram , Mitko Veta , Christian Marzahl , Nikolas Stathonikos , Andreas Maier , Robert Klopfleisch , Marc Aubreville

Noise has always been nonnegligible trouble in object detection by creating confusion in model reasoning, thereby reducing the informativeness of the data. It can lead to inaccurate recognition due to the shift in the observed pattern, that…

Computer Vision and Pattern Recognition · Computer Science 2023-04-25 Xinyu Zhang , Zhiwei Li , Zhenhong Zou , Xin Gao , Yijin Xiong , Dafeng Jin , Jun Li , Huaping Liu

The privacy protection mechanism of federated learning (FL) offers an effective solution for cross-center medical collaboration and data sharing. In multi-site medical image segmentation, each medical site serves as a client of FL, and its…

Image and Video Processing · Electrical Eng. & Systems 2023-06-30 Fubao Zhu , Yanhui Tian , Chuang Han , Yanting Li , Jiaofen Nan , Ni Yao , Weihua Zhou

Deep unsupervised approaches are gathering increased attention for applications such as pathology detection and segmentation in medical images since they promise to alleviate the need for large labeled datasets and are more generalizable…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Ioannis Lagogiannis , Felix Meissen , Georgios Kaissis , Daniel Rueckert

Multi-disease diagnosis using multi-modal data like electronic health records and medical imaging is a critical clinical task. Although existing deep learning methods have achieved initial success in this area, a significant gap persists…

Multimedia · Computer Science 2025-09-22 Yueheng Jiang , Peng Zhang

The domain shift between training and testing data presents a significant challenge for training generalizable deep learning models. As a consequence, the performance of models trained with the independent and identically distributed…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Aleksandr Matsun , Dana O. Mohamed , Sharon Chokuwa , Muhammad Ridzuan , Mohammad Yaqub

Machine learning algorithms have the potential to improve patient outcomes in digital pathology. However, generalization of these tools is currently limited by sensitivity to variations in tissue preparation, staining procedures and…

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Tengyue Zhang , Ruiwen Ding , Luoting Zhuang , Yuxiao Wu , Erika F. Rodriguez , William Hsu

Solving medical imaging data scarcity through semantic image generation has attracted growing attention in recent years. However, existing generative models mainly focus on synthesizing whole-organ or large-tissue structures, showing…

Image and Video Processing · Electrical Eng. & Systems 2025-12-19 Jiahao Xia , Yutao Hu , Yaolei Qi , Zhenliang Li , Wenqi Shao , Junjun He , Ying Fu , Longjiang Zhang , Guanyu Yang

Accurate detection of diseased glomeruli is fundamental to progress in renal pathology and underpins the delivery of reliable clinical diagnoses. Although recent advances in computer vision have produced increasingly sophisticated detection…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Tianyu Shi , Xinzi He , Kenji Ikemura , Mert R. Sabuncu , Yihe Yang , Ruining Deng

Histopathology can help clinicians make accurate diagnoses, determine disease prognosis, and plan appropriate treatment strategies. As deep learning techniques prove successful in the medical domain, the primary challenges become limited…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Zhe Li , Bernhard Kainz

Out-of-distribution (OOD) detection is a crucial task for ensuring the reliability and safety of deep learning. Currently, discriminator models outperform other methods in this regard. However, the feature extraction process used by…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Luping Liu , Yi Ren , Xize Cheng , Rongjie Huang , Chongxuan Li , Zhou Zhao

Supervised 3D Object Detection models have been displaying increasingly better performance in single-domain cases where the training data comes from the same environment and sensor as the testing data. However, in real-world scenarios data…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Louis Soum-Fontez , Jean-Emmanuel Deschaud , François Goulette
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