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Topological defects play a prominent role in the physics of two-dimensional materials. When driven out of equilibrium in active nematics, disclinations can acquire spontaneous self-propulsion and drive self-sustained flows upon…

Soft Condensed Matter · Physics 2019-12-06 Suraj Shankar , M. Cristina Marchetti

Topological defects are at the root of the large-scale organization of liquid crystals. In two-dimensional active nematics, two classes of topological defects of charges $\pm 1/2$ are known to play a major role due to active stresses.…

Soft Condensed Matter · Physics 2022-04-08 Louis Brézin , Thomas Risler , Jean-François Joanny

Active fluids display spontaneous turbulent-like flows known as active turbulence. Recent work revealed that these flows have universal features, independent of the material properties and of the presence of topological defects. However,…

Soft Condensed Matter · Physics 2026-03-19 Ido Lavi , Ricard Alert , Jean-François Joanny , Jaume Casademunt

Collectively moving cellular systems often contain a proportion of dead cells or non-motile genotypes. When mixed, nematically aligning motile and non-motile agents are known to segregate spontaneously. However, the role that topological…

We formulate the statistical dynamics of topological defects in the active nematic phase, formed in two dimensions by a collection of self-driven particles on a substrate. An important consequence of the non-equilibrium drive is the…

Soft Condensed Matter · Physics 2018-09-12 Suraj Shankar , Sriram Ramaswamy , M. Cristina Marchetti , Mark J. Bowick

A nematic liquid crystal confined to the surface of a sphere exhibits topological defects of total charge $+2$ due to the topological constraint. In equilibrium, the nematic field forms four $+1/2$ defects, located at the corners of a…

Soft Condensed Matter · Physics 2020-07-22 Yi-Heng Zhang , Markus Deserno , Zhan-Chun Tu

The self-propulsion of +1/2 topological defects is a hallmark of active nematic fluids, where the defects are advected by the flow field they themselves generate. In this paper we propose a minimal model for defect self-propulsion in a…

Soft Condensed Matter · Physics 2025-08-08 Fridtjof Brauns , Myles O'Leary , Arthur Hernandez , Mark J. Bowick , M. Cristina Marchetti

Topological defects play a key role in two-dimensional active nematics, and a transient role in two-dimensional active polar fluids. In this paper, we study both the transient and long-time behavior of defects in two-dimensional active…

Soft Condensed Matter · Physics 2020-09-24 Farzan Vafa

Point-like motile topological defects control the universal dynamics of diverse two-dimensional active nematics ranging from shaken granular rods to cellular monolayers. A comparable understanding in higher dimensions has yet to emerge. We…

Active nematics are fluids in which the components have nematic symmetry and are driven out of equilibrium due to the microscopic generation of an active stress. When the active stress is high, it drives flows in the nematic and can lead to…

Soft Condensed Matter · Physics 2025-11-10 Daniel J. G. Pearce , Berta Martínez-Prat , Jordi Ignés-Mullol , Francesc Sagués

Topological defects in active liquid crystals can be confined by introducing gradients of activity. Here, we examine the dynamical behavior of two defects confined by a sharp gradient of activity that separates an active circular region and…

Soft Condensed Matter · Physics 2021-06-16 Ali Mozaffari , Rui Zhang , Noe Atzin , Juan J. de Pablo

Active fluids, such as cytoskeletal filaments, bacterial colonies and epithelial cell layers, exhibit distinctive orientational coherence, often characterized by nematic order and topological defects. By contrast, little is known about…

Soft Condensed Matter · Physics 2021-04-07 Mattia Serra , Linnea Lemma , Luca Giomi , Zvonimir Dogic , L. Mahadevan

Living materials at different length scales manifest active nematic features such as orientational order, nematic topological defects, and active nematic turbulence. Using numerical simulations we investigate the impact of fluid inertia on…

Soft Condensed Matter · Physics 2022-08-10 Roozbeh Saghatchi , Mehmet Yildiz , Amin Doostmohammadi

We propose an agent-based model of active flexible rods. Inspired by cytoskeletal flows, we introduce activity by an internal flow that contributes to the dissipative forces. The active force between our agents is central and reciprocal,…

Soft Condensed Matter · Physics 2026-03-06 Mathieu Dedenon , Carles Blanch-Mercader , Karsten Kruse , Jens Elgeti

Using agent-based simulations of self-propelled particles subject to short-range repulsion and nematic alignment we explore the dynamical phases of a dense active material confined to the surface of a sphere. We map the dynamical phase…

Soft Condensed Matter · Physics 2018-04-25 Silke Henkes , M. Cristina Marchetti , Rastko Sknepnek

Recent experiments and numerical studies have drawn attention to the dynamics of active nematics. Two-dimensional active nematics flow spontaneously and exhibit spatiotemporal chaotic flows with proliferation of topological defects in the…

Soft Condensed Matter · Physics 2020-07-08 Farzan Vafa , Mark J. Bowick , M. Cristina Marchetti , Boris I. Shraiman

The study of liquid crystals at equilibrium has led to fundamental insights into the nature of ordered materials, as well as to practical applications such as display technologies. Active nematics are a fundamentally different class of…

Soft Condensed Matter · Physics 2015-08-19 Stephen J. DeCamp , Gabriel S. Redner , Aparna Baskaran , Michael F. Hagan , Zvonimir Dogic

We present a hydrodynamic model for a thin spherical shell of active nematic liquid crystal with an arbitrary configuration of defects. The active flows generated by defects in the director lead to the formation of stable vortices,…

Soft Condensed Matter · Physics 2017-11-13 Diana Khoromskaia , Gareth P. Alexander

Cultured stem cells have become a standard platform not only for regenerative medicine and developmental biology but also for biophysical studies. Yet, the characterization of cultured stem cells at the level of morphology and macroscopic…

Soft Condensed Matter · Physics 2022-06-23 Kyogo Kawaguchi , Ryoichiro Kageyama , Masaki Sano

We study a continuum model of an extensile active nematic to show that mesoscale turbulence develops in two stages: (i) ordered regions undergo an intrinsic hydrodynamic instability generating walls, lines of stong bend deformations, (ii)…

Soft Condensed Matter · Physics 2015-06-18 Sumesh P. Thampi , Ramin Golestanian , Julia M. Yeomans
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