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For centuries isolation has been the main control strategy of unforeseen epidemic outbreaks. When implemented in full and without delay, isolation is very effective. However, flawless implementation is seldom feasible in practice. We…

Populations and Evolution · Quantitative Biology 2019-01-23 Lai-Sang Young , Stefan Ruschel , Serhiy Yanchuk , Tiago Pereira

The intersection of machine learning and dynamical systems has generated considerable interest recently. Neural Ordinary Differential Equations (NODEs) represent a rich overlap between these fields. In this paper, we develop a continuous…

Optimization and Control · Mathematics 2023-06-16 Maria Oprea , Mark Walth , Robert Stephany , Gabriella Torres Nothaft , Arnaldo Rodriguez-Gonzalez , William Clark

Recently, various evolutionary partial differential equations (PDEs) with a mixed derivative have been emerged and drawn much attention. Nonetheless, their PDE-theoretical and numerical studies are still in their early stage. In this paper,…

Numerical Analysis · Mathematics 2017-12-12 Shun Sato , Takayasu Matsuo

The optimization of the latents and parameters of diffusion models with respect to some differentiable metric defined on the output of the model is a challenging and complex problem. The sampling for diffusion models is done by solving…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Zander W. Blasingame , Chen Liu

Recurrent neural networks (RNNs) are particularly well-suited for modeling long-term dependencies in sequential data, but are notoriously hard to train because the error backpropagated in time either vanishes or explodes at an exponential…

Machine Learning · Computer Science 2019-08-28 Anil Kag , Ziming Zhang , Venkatesh Saligrama

In a recent paper we presented a general perturbation result for generators of $C_0$-semigroups. The aim of the present paper is to replace, in case the unperturbed semigroup is analytic, the various conditions appearing in this result by…

Functional Analysis · Mathematics 2015-05-07 Martin Adler , Miriam Bombieri , Klaus-Jochen Engel

The spread of many infectious diseases is modeled using variants of the SIR compartmental model, which is a coupled differential equation. The coefficients of the SIR model determine the spread trajectories of disease, on whose basis…

Machine Learning · Computer Science 2023-03-28 Ritam Majumdar , Shirish Karande , Lovekesh Vig

Neurodegenerative diseases are characterized by the accumulation of misfolded proteins and widespread disruptions in brain function. Computational modeling has advanced our understanding of these processes, but efforts have traditionally…

A family of discrete non-autonomous SIRVS models with general incidence is obtained from a continuous family of models by applying Mickens non-standard discretization method. Conditions for the permanence and extinction of the disease and…

Dynamical Systems · Mathematics 2018-03-02 Joaquim Mateus , César Silva , Sandra Vaz

Infectious diseases are among the most prominent threats to mankind. When preventive health care cannot be provided, a viable means of disease control is the isolation of individuals, who may be infected. To study the impact of isolation,…

Dynamical Systems · Mathematics 2018-04-10 Stefan Ruschel , Tiago Pereira , Serhiy Yanchuk , Lai-Sang Young

As a fundamental mathmatical tool in many engineering disciplines, coupled differential equation groups are being widely used to model complex structures containing multiple physical quantities. Engineers constantly adjust structural…

Machine Learning · Computer Science 2023-06-26 Wenhao Ding , Qing He , Hanghang Tong , Qingjing Wang , Ping Wang

In this paper we generalize the Deuring theorem on a reduction of elliptic curve with complex multiplication. More precisely, for an Abelian variety $A$, arising after reduction of an Abelian variety with complex multiplication by a CM…

Algebraic Geometry · Mathematics 2012-09-25 Alexey Zaytsev

Reaction networks are commonly used within the mathematical biology and mathematical chemistry communities to model the dynamics of interacting species. These models differ from the typical graphs found in random graph theory since their…

Probability · Mathematics 2021-06-23 David F. Anderson , Tung D. Nguyen

In this chapter, we consider a reaction-diffusion SVIR infection model with dis-tributed delay and nonlinear incidence rate. The wellposedness of the proposed model is proved. By means of Lyapunov functionals, we show that the disease-free…

Dynamical Systems · Mathematics 2025-03-10 Achraf Zinihi , Mostafa Tahiri , Moulay Rchid Sidi Ammi

Conditional density estimation (CDE) is the task of estimating the probability of an event conditioned on some inputs. A neural network (NN) can also be used to compute the output distribution for continuous-domain, which can be viewed as…

Machine Learning · Computer Science 2021-12-30 Bing Chen , Mazharul Islam , Jisuo Gao , Lin Wang

We adapt the article of Forien, Pang, Pardoux and Zotsa: Arxiv preprint Arxiv2210.04667(2022), on epidemic models with varying infectivity and waning immunity, to incorporate the memory of the last infection. To this end, we introduce a…

Probability · Mathematics 2025-05-02 Hélène Guérin , Arsene Brice Zotsa-Ngoufack

This paper considers the classical Susceptible--Infected--Susceptible (SIS) network epidemic model, which describes a disease spreading through $n$ nodes, with the network links governing the possible transmission pathways of the disease…

Systems and Control · Electrical Eng. & Systems 2023-05-29 Liam Walsh , Mengbin Ye , Brian D. O. Anderson , Zhiyong Sun

Asymptotic dynamics of ordinary differential equations (ODEs) are commonly understood by looking at eigenvalues of a matrix, and transient dynamics can be bounded above and below by considering the corresponding pseudospectra. While…

Numerical Analysis · Mathematics 2016-11-17 Amanda Hood , David Bindel

We present a unifying, tractable approach for studying the spread of viruses causing complex diseases requiring to be modeled using a large number of types (e.g., infective stage, clinical state, risk factor class). We show that recording…

Mean-field systems have been previously derived for networks of coupled, two-dimensional, integrate-and-fire neurons such as the Izhikevich, adapting exponential (AdEx) and quartic integrate and fire (QIF), among others. Unfortunately, the…

Neurons and Cognition · Quantitative Biology 2016-05-19 Wilten Nicola , Cheng Ly , Sue Ann Campbell
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