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In the rapidly evolving field of optical engineering, precise alignment of multi-lens imaging systems is critical yet challenging, as even minor misalignments can significantly degrade performance. Traditional alignment methods rely on…

Optics · Physics 2025-07-01 Tomer Slor , Dean Oren , Shira Baneth , Tom Coen , Haim Suchowski

We present a generic algorithm for performing astronomical image registration and pointing refinement. The method is based on matching the positions and fluxes of available point sources in image overlap regions. This information is used to…

Astrophysics · Physics 2009-11-10 Frank J. Masci , David Makovoz , Mehrdad Moshir

Adaptive optics (AO) instruments for the future extremely large telescopes (ELTs) are characterized by advanced optical systems with diffraction-limited optical quality. Low geometric distortion is also crucial for high accuracy astrometric…

Instrumentation and Methods for Astrophysics · Physics 2019-04-02 Mauro Patti , Matteo Lombini , Edoardo Maria Alberto Redaelli , Emiliano Diolaiti

The technique of remote refocusing is used in optical microscopy to provide rapid axial scanning without mechanically perturbing the sample and in techniques such as oblique plane microscopy that build on remote refocusing to image a tilted…

Optics · Physics 2023-09-27 Wenzhi Hong , Hugh Sparks , Chris Dunsby

We describe the optical alignment method for the Prime-focus Infrared Microlensing Experiment (PRIME) telescope which is a prime-focus near-infrared (NIR) telescope with a wide field of view for the microlensing planet survey toward the…

Instrumentation and Methods for Astrophysics · Physics 2023-05-22 Hibiki Yama , Daisuke Suzuki , Shota Miyazaki , Andrew Rakich , Tsubasa Yamawaki , Rintaro Kirikawa , Iona Kondo , Yuki Hirao , Naoki Koshimoto , Takahiro Sumi

Optical microscopy contributes to the ever-increasing progress in biological and biomedical studies, as it allows the implementation of minimally invasive experimental pipelines to translate the data of measured samples into valuable…

Quantitative Methods · Quantitative Biology 2025-04-03 Elena Corbetta , Thomas Bocklitz

Automation of alignment tasks can provide improved efficiency and greatly increase the flexibility of an optical system. Current optical systems with automated alignment capabilities are typically designed to include a dedicated wavefront…

Instrumentation and Methods for Astrophysics · Physics 2016-08-31 Joyce Fang , Dmitry Savransky

This work addresses image restoration tasks through the lens of inverse problems using unpaired datasets. In contrast to traditional approaches -- which typically assume full knowledge of the forward model or access to paired degraded and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Giacomo Meanti , Thomas Ryckeboer , Michael Arbel , Julien Mairal

Modeling of microlensing events poses computational challenges for the resolution of the lens equation and the high dimensionality of the parameter space. In particular, numerical noise represents a severe limitation to fast and efficient…

Instrumentation and Methods for Astrophysics · Physics 2025-02-19 V. Bozza , V. Saggese , G. Covone , P. Rota , J. Zhang

Adaptive optics is a strategy to compensate for sample-induced aberrations in microscopy applications. Generally, it requires the presence of "guide stars" in the sample to serve as localized reference targets. We describe an implementation…

Task arithmetic enables efficient model editing by representing task-specific changes as vectors in parameter space. Task arithmetic typically assumes that the source and target models are initialized from the same pre-trained parameters.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Kazuhiko Kawamoto , Atsuhiro Endo , Hiroshi Kera

Adaptive optics (AO) is a powerful image correction technique with proven benefits for many life-science microscopy methods. However, the complexity of adding a reflective wavefront modulator and a wavefront sensor into already complicated…

Deep learning for object classification relies heavily on convolutional models. While effective, CNNs are rarely interpretable after the fact. An attention mechanism can be used to highlight the area of the image that the model focuses on…

Computer Vision and Pattern Recognition · Computer Science 2019-03-18 Paresh Malalur , Tommi Jaakkola

The resolution and contrast of microscope imaging is often affected by aberrations introduced by imperfect optical systems and inhomogeneous refractive structures in specimens. Adaptive optics (AO) compensates these aberrations and restores…

In contemporary imaging systems, achieving optimal auto-focus (AF) performance hinges on precise lens positioning. Extensive research has delved into refining algorithms for determining the ideal lens position across passive, active, and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Ali Karaoglu

Adaptive optics in combination with multi-photon techniques is a powerful approach to image deep into a specimen. Remarkably, virtually all adaptive optics schemes today rely on wavefront modulators which are reflective, diffractive, or…

Reliable, autonomously, deployment of telescopes enables a wide range of possible science cases. In this paper, we present a method for multi-stage telescope alignment with a simple commercial imaging sensor. For these studies, we use a…

Instrumentation and Methods for Astrophysics · Physics 2025-08-28 Solvay Blomquist , Heejoo Choi , Hyukmo Kang , Hayden Kim , Kevin Derby , Pierre Nicolas , Joanna Rosenbluth , Patrick Ingraham , Ewan S. Douglas , Daewook Kim

Oblique plane microscopy is a method enabling light-sheet fluorescence imaging through a single microscope objective lens by focusing on a tilted plane within the sample. To focus the fluorescence emitted by the oblique plane on a camera,…

To enhance the resolution of a confocal laser scanning microscope the additional information of a pinhole plane image taken at every excitation scan position can be used [C. J. R. Sheppard, Super-resolution in confocal imaging, Optik 80,…

Optics · Physics 2013-06-27 Stephan Roth , Colin J. R. Sheppard , Kai Wicker , Rainer Heintzmann

Aberrations limit scanning fluorescence microscopy when imaging in scattering materials such as biological tissue. Model-based approaches for adaptive optics take advantage of a computational model of the optical setup. Such models can be…

Optics · Physics 2021-07-07 Ivan Vishniakou , Johannes D. Seelig
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