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Accurate localization of myocardial infarction is essential for risk stratification. While LGE-MRI remains the gold standard, it is resource-intensive. Integrating cine MRI with ECG enables a more detailed representation of infarct…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Mengxiao Wang , Yilin Lyu , Julia Camps , Ching Hui Sia , Mark Yan-Yee Chan , Yanrui Jin , Shuzhi Sam Ge , Chengliang Liu , Lei Li

Cardiac digital twins (CDTs) are personalized virtual representations used to understand complex cardiac mechanisms. A critical component of CDT development is solving the ECG inverse problem, which enables the reconstruction of cardiac…

Computer Vision and Pattern Recognition · Computer Science 2024-09-16 Lei Li , Julia Camps , Blanca Rodriguez , Vicente Grau

Patient-specific cardiac computational models are essential for the efficient realization of precision medicine and in-silico clinical trials using digital twins. Cardiac digital twins can provide non-invasive characterizations of cardiac…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Lei Li , Julia Camps , Abhirup Banerjee , Marcel Beetz , Blanca Rodriguez , Vicente Grau

Digital twins for cardiac electrophysiology are an enabling technology for precision cardiology. Current forward models are advanced enough to simulate the cardiac electric activity under different pathophysiological conditions and…

Optimization and Control · Mathematics 2025-05-05 Thomas Grandits , Karli Gillette , Gernot Plank , Simone Pezzuto

This study develops a Convolutional Neural Network (CNN) model for detecting myocardial infarction (MI) from Electrocardiogram (ECG) images. The model, built using the InceptionV3 architecture and optimized through transfer learning, was…

Objective: We aim to provide an algorithm for the detection of myocardial infarction that operates directly on ECG data without any preprocessing and to investigate its decision criteria. Approach: We train an ensemble of fully…

Computers and Society · Computer Science 2019-02-06 Nils Strodthoff , Claas Strodthoff

. In this paper, an effective computer-aided diagnosis (CAD) system is presented to detect MI signals using the convolution neural network (CNN) for urban healthcare in smart cities. Two types of transfer learning techniques are employed to…

Cardiac digital twins (CDTs) of human cardiac electrophysiology (EP) are digital replicas of patient hearts that match like-for-like clinical observations. The electrocardiogram (ECG), as the most prevalent non-invasive observation of…

Medical Physics · Physics 2024-07-26 Elena Zappon , Matthias A. F. Gsell , Karli Gillette , Gernot Plank

Cardiac digital twins are computational tools capturing key functional and anatomical characteristics of patient hearts for investigating disease phenotypes and predicting responses to therapy. When paired with large-scale computational…

Computational Engineering, Finance, and Science · Computer Science 2024-01-19 Julia Camps , Zhinuo Jenny Wang , Ruben Doste , Maxx Holmes , Brodie Lawson , Jakub Tomek , Kevin Burrage , Alfonso Bueno-Orovio , Blanca Rodriguez

Background and Objective: Precise preoperative planning and effective physician training for coronary interventions are increasingly important. Despite advances in medical imaging technologies, transforming static or limited dynamic imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Shuo Wang , Tong Ren , Nan Cheng , Rong Wang , Li Zhang

A cardiac digital twin is a virtual replica of a patient-specific heart, mimicking its anatomy and physiology. A crucial step of building a cardiac digital twin is anatomical twinning, where the computational mesh of the digital twin is…

Myocardial infarction (MI) is a leading cause of death, and its adverse outcomes are urgent to predict. Yet ECG-based prognostic models underperform because deep learning requires large, labelled datasets, which are scarce in medicine.…

Cardiac digital twins (CDTs) provide personalized in-silico cardiac representations and hold great potential for precision medicine in cardiology. However, whole-heart CDT models that simulate the full organ-scale electromechanics of all…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Xiaoyue Liu , Xicheng Sheng , Xiahai Zhuang , Vicente Grau , Mark YY Chan , Ching-Hui Sia , Lei Li

Myocardial infarction is the leading cause of death worldwide. In this paper, we design domain-inspired neural network models to detect myocardial infarction. First, we study the contribution of various leads. This systematic analysis,…

Machine Learning · Computer Science 2021-01-27 Arjun Gupta , E. A. Huerta , Zhizhen Zhao , Issam Moussa

This work evaluates deep learning-based myocardial infarction (MI) quantification using Segment cardiovascular magnetic resonance (CMR) software. Segment CMR software incorporates the expectation-maximization, weighted intensity, a priori…

Image and Video Processing · Electrical Eng. & Systems 2021-09-03 Olivier Rukundo

Myocardial Infarction (MI) has the highest mortality of all cardiovascular diseases (CVDs). Detection of MI and information regarding its occurrence-time in particular, would enable timely interventions that may improve patient outcomes,…

Signal Processing · Electrical Eng. & Systems 2021-04-06 Girmaw Abebe Tadesse , Hamza Javed , Yong Liu , Jin Liu , Jiyan Chen , Komminist Weldemariam , Tingting Zhu

Cardiac digital twins (CDTs) offer personalized in-silico cardiac representations for the inference of multi-scale properties tied to cardiac mechanisms. The creation of CDTs requires precise information about the electrode position on the…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Lei Li , Hannah Smith , Yilin Lyu , Julia Camps , Shuang Qian , Blanca Rodriguez , Abhirup Banerjee , Vicente Grau

The realisation of precision cardiology requires novel techniques for the non-invasive characterisation of individual patients' cardiac function to inform therapeutic and diagnostic decision-making. The electrocardiogram (ECG) is the most…

Tissues and Organs · Quantitative Biology 2021-12-09 Julia Camps , Brodie Lawson , Christopher Drovandi , Ana Minchole , Zhinuo Jenny Wang , Vicente Grau , Kevin Burrage , Blanca Rodriguez

Myocardial infarction (MI) results in heart muscle injury due to receiving insufficient blood flow. MI is the most common cause of mortality in middle-aged and elderly individuals around the world. To diagnose MI, clinicians need to…

Cardiac arrest is one of the biggest global health problems, and early identification and management are key to enhancing the patient's prognosis. In this paper, we propose a novel framework that combines an EfficientNet-based deep learning…

Machine Learning · Computer Science 2025-09-10 Qasim Zia , Avais Jan , Zafar Iqbal , Muhammad Mumtaz Ali , Mukarram Ali , Murray Patterson
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